Results 51 to 60 of about 112,379 (307)

Elastin degradation products in acute lung injury induced by gastric contents aspiration

open access: yesRespiratory Research, 2018
Background Gastric contents aspiration is a high-risk condition for acute lung injury (ALI). Consequences range from subclinical pneumonitis to respiratory failure, depending on the volume of aspirate.
Pedro Ayala   +5 more
doaj   +1 more source

A model for the anisotropic response of fibrous soft tissues using six discrete fibre bundles [PDF]

open access: yes, 2010
The development of accurate constitutive models of fibrous soft-tissues is a challenging problem. Many consider the tissue to be a collection of fibres with a continuous distribution function representing their orientations. A novel discrete fibre model
Flynn, C., Nielsen, P., Rubin, M. B.
core   +1 more source

Elastin a Sialoprotein [PDF]

open access: yesNature, 1962
THE aorta consists of elastin, collagen and a number of other proteins; it also contains about 2 per cent of carbohydrate1. Elastin is usually isolated from aorta or ligamentum nuchae by treatment with acids and alkalis at elevated temperatures; however, a small amount of ill-defined carbohydrate appears to be held strongly and cannot be easily ...
openaire   +2 more sources

From Clinic to Computation: Multiscale Bioengineering Strategies for Durable Biological Aortic Valve Replacements

open access: yesAdvanced Functional Materials, EarlyView.
Bioprosthetic aortic valves have revolutionized the treatment of aortic stenosis, but their durability is limited by structural valve deterioration (SVD). This review focuses on the pericardial tissue at the heart of these valves, examining how its mechanical properties and calcification drive fatigue and failure.
Gabriele Greco   +7 more
wiley   +1 more source

Time-sequential fibroblast-to-myofibroblast transition in elastin-variable 3D hydrogel environments by collagen networks

open access: yesBiomaterials Research, 2023
Background Fibrosis plays an important role in both normal physiological and pathological phenomena as fibroblasts differentiate to myofibroblasts. The activation of fibroblasts is determined through interactions with the surrounding extracellular matrix
Nhuan T. Do   +7 more
doaj   +1 more source

In Situ 3D Bioprinting: Impact of Cross‐Linking on the Adhesive Properties of Hydrogels

open access: yesAdvanced Functional Materials, EarlyView.
In situ 3D bioprinting enables the direct deposition of cell‐laden, adhesive biomaterials for on‐site tissue regeneration. This review provides a comprehensive overview of how cross‐linking influences the bioadhesive properties of hydrogels used in 3D bioprinting, highlighting cross‐linking triggers, bioadhesion mechanisms, polymer interpenetration ...
Odile Romero Fernandez   +4 more
wiley   +1 more source

The liquid structure of elastin

open access: yeseLife, 2017
The protein elastin imparts extensibility, elastic recoil, and resilience to tissues including arterial walls, skin, lung alveoli, and the uterus. Elastin and elastin-like peptides are hydrophobic, disordered, and undergo liquid-liquid phase separation ...
Sarah Rauscher, Régis Pomès
doaj   +1 more source

In Vitro and In Silico Studies on Angiotensin I-Converting Enzyme Inhibitory Peptides Found in Hydrophobic Domains of Porcine Elastin

open access: yesMolecules, 2023
One of the most striking aspects of the primary structure in the hydrophobic domains of the tropoelastin molecule is the occurrence of the VAPGVG repeating sequence.
Toshiya Hatakenaka   +2 more
doaj   +1 more source

Matrikines are key regulators in modulating the amplitude of lung inflammation in acute pulmonary infection [PDF]

open access: yes, 2015
Bioactive matrix fragments (matrikines) have been identified in a myriad of disorders, but their impact on the evolution of airway inflammation has not been demonstrated.
Snelgrove, RJ
core   +1 more source

A mammalian Wnt5a-Ror2-Vangl2 axis controls the cytoskeleton and confers cellular properties required for alveologenesis. [PDF]

open access: yes, 2020
Alveolar formation increases the surface area for gas-exchange and is key to the physiological function of the lung. Alveolar epithelial cells, myofibroblasts and endothelial cells undergo coordinated morphogenesis to generate epithelial folds (secondary
Chou, Yu-Ting   +7 more
core   +1 more source

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