Results 31 to 40 of about 57,913 (262)

Elastin‐Specific Autoimmunity in Smokers With Thoracic Aortic Aneurysm and Dissection is Independent of Chronic Obstructive Pulmonary Disease

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Thoracic aortic aneurysm (TAA) and dissection (TAD) are characterized by progressive disorganization of the aortic wall matrix, including elastin, a highly immunogenic molecule.
Bon‐Hee Gu   +11 more
doaj   +1 more source

Biomimetic Vascular Scaffold with Seamless Electrospun Aligned Nanofiber Conduit and 3D‐Printed Coil Reinforcement

open access: yesAdvanced Healthcare Materials, EarlyView.
We introduce a new fabrication method that overcomes the current limitation of tubular gap electrospinning. We successfully fabricated a seamless hollow tube with fibers aligned along the longitudinal axis in diameters as small as 300 µm, and then reinforced it using 4‐axis 3D printing.
Seyed Aliakbar Hosseini Toopghara   +9 more
wiley   +1 more source

PKCε Increases Extracellular Elastin and Fibulin-5/DANCE in Dermal Fibroblasts

open access: yesCellular Physiology and Biochemistry, 2018
Background/Aims: In the earlier study, the selective PKCε activator DCP-LA increased elastic fibres in the dermis of HR-1 hairless mice. As a process of elastic fibre formation, tropoelastin, an elastin monomer, is secreted into the extracellular space ...
Tomoyuki Nishizaki
doaj   +1 more source

Elastin as a rubber

open access: yesBiopolymers, 1977
AbstractThe thermoelastic behavior of water solvated elastin has been investigated in simple tension, in the temperature range 0–70°C. Specimens purified from both the ox ligamentum nuchae and pig thoracic aorta have been studied. Force data obtained by cycling the temperature for various constant specimen lengths display a separated variable ...
Dorrington, K, McCrum, N
openaire   +2 more sources

Boolean Logic‐Based Control Over Recombinant Protein Biomaterial Degradability and Therapeutic Delivery

open access: yesAdvanced Materials, EarlyView.
Fully recombinant protein‐based biomaterials execute complex Boolean logic for user‐programmable material degradation and concomitant therapeutic cargo release. Biologics, such as growth factors, can be incorporated within the crosslinkers as “drugamers”, while encapsulated cells can be released according to nested YES/OR/AND‐type logical operations ...
Murial L. Ross   +3 more
wiley   +1 more source

Elastin degradation products in acute lung injury induced by gastric contents aspiration

open access: yesRespiratory Research, 2018
Background Gastric contents aspiration is a high-risk condition for acute lung injury (ALI). Consequences range from subclinical pneumonitis to respiratory failure, depending on the volume of aspirate.
Pedro Ayala   +5 more
doaj   +1 more source

Biointegrated Battery‐Based Electroceuticals

open access: yesAdvanced Materials, EarlyView.
Biointegrated batteries go beyond passive power to serve as active therapeutic platforms for delivering programmable electrical cues and bioactive agents. This review examines their mechanisms and applications and provides a framework to guide battery‐based therapeutic design and clinical translation.
Yan Zhou   +6 more
wiley   +1 more source

In Vitro and In Silico Studies on Angiotensin I-Converting Enzyme Inhibitory Peptides Found in Hydrophobic Domains of Porcine Elastin

open access: yesMolecules, 2023
One of the most striking aspects of the primary structure in the hydrophobic domains of the tropoelastin molecule is the occurrence of the VAPGVG repeating sequence.
Toshiya Hatakenaka   +2 more
doaj   +1 more source

Extrusion Bioprinting for Wound Healing: Innovations in Functionalized Bioinks and Bioprinting Technology

open access: yesAdvanced Materials Technologies, EarlyView.
Extrusion‐based bioprinting (EBB) has emerged as a versatile biofabrication platform capable of precisely depositing bioinks composed of biomaterials, cells, and bioactive agents to generate patient‐specific, biomimetic skin constructs. This paper presents a state‐of‐the‐art and forward‐looking overview of EBB for wound healing, encompassing printing ...
Hien‐Phuong Le   +4 more
wiley   +1 more source

Applications of Elastin in Cosmetics: Prospects and Challenges

open access: yesCosmetics
Elastin is a crucial component of the extracellular matrix that plays a significant role in maintaining skin elasticity and firmness. Within the dermis, elastin works in collaboration with collagen to form supportive structures that contribute to the ...
Ting Lei   +4 more
doaj   +1 more source

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