Results 31 to 40 of about 112,280 (209)

Platelet-derived transforming growth factor-β1 promotes keratinocyte proliferation in cutaneous wound healing. [PDF]

, 2020
Platelets are a recognised potent source of transforming growth factor-β1 (TGFβ1), a cytokine known to promote wound healing and regeneration by stimulating dermal fibroblast proliferation and extracellular matrix deposition.
Chong, DLW, Holmes, AM, Hughes, S, Labelle, M, Porter, JC, Rodriguez-Justo, M, Scotton, CJ, Trinder, S   +7 more
core   +3 more sources

Bioactive recombinant human elastin gel for reconstructing elastic fibers and rejuvenating endogenously aged skin

Materials Today Bio
Endogenous skin aging results in oxidative stress and degradation of elastic fibers, leading to reduced skin elasticity and dermal laxity. Current treatments rarely target elastic fiber regeneration.
Yi Yang, Wenjie Huang, Jingjing Shi, Bei Tian, Caihong Fu, Jianxi Xiao   +5 more
doaj   +1 more source

Layer-by-layer biofabrication of coronary covered stents with clickable elastin-like recombinamers [PDF]

, 2019
Producción CientíficaCoronary artery disease is the leading cause of death around the world. Endovascular stenting is the preferred treatment option to restore blood flow in the coronary arteries due to the lower perioperative morbidity when compared ...
Fernández Colino, Alicia, Jockenhoevel, Stefan, Mela, Petra, Moreira, Ricardo, Rodríguez Cabello, José Carlos, Rütten, Stephan, Schmitz-Rode, Thomas, Wolf, Frederic   +7 more
core   +2 more sources

Elastin genetic point mutation and the risk of pelvic organ prolapse

Clinical and Experimental Obstetrics & Gynecology, 2020
Aim: A missense mutation in the elastin gene (g28197A > G) is associated with an increased risk for inguinal hernias. Due to the shared epidemiological and pathophysiological features between pelvic organ prolapse (POP) and inguinal hernias, the authors ...
N. Haya, I. Feferkorn, F. Fares, N. Azzam, R. Auslender, Y. Abramov   +5 more
doaj   +1 more source

Pulmonary artery stiffness in chronic obstructive pulmonary disease (copd) and emphysema: The Multi-Ethnic Study of Atherosclerosis (MESA) COPD Study [PDF]

, 2018
Purpose: Chronic obstructive pulmonary disease (COPD) and particularly emphysema are characterized by stiffness of the aorta, due in part to accelerated elastin degradation in the lungs and aorta. Stiffness of the pulmonary arteries (PAs) may also be
Balte, Pallavi, Barr, R. Graham, Bluemke, David A., Carr, James, Dashnaw, Stephen, Gomes, Antoinette S., Hoffman, Eric A., Kawut, Steven M., Lima, Joao A.C., Liu, Chia-Ying, McAllister, David A., Parikh, Megha, Poor, Hooman D.   +12 more
core   +1 more source

Elastin and Elastase [PDF]

Nature, 1953
IN previous publications1,2, we reported that extracts of animal pancreas made with fluids of different pH exhibit varying elastolytic activity (e.u./gm.) on account of the presence of elastase inhibitor, which in the pancreas is bound to elastase3. In crude neutral solution, the activation of elastase may be carried out by acidification, dialysis or ...
I, BANGA, J, BALO
openaire   +2 more sources

Research on the expression of elastin in the conjoint fascial sheath for the correction of severe unilateral congenital blepharoptosis

BMC Ophthalmology, 2022
Background To investigate the expression of elastin in the conjoint facial sheath (CFS) in patients with severe unilateral congenital blepharoptosis in different age groups.
Zhaochuan Liu, Xin Jia, Runhui Pang, Huixing Wang, Junhu Shi, Ping Bai   +5 more
doaj   +1 more source

Serological assessment of neutrophil elastase activity on elastin during lung ECM remodeling [PDF]

, 2015
BACKGROUND: During the pathological destruction of lung tissue, neutrophil elastase (NE) degrades elastin, one of the major constituents of lung parenchyma. However there are no non-invasive methods to quantify NE degradation of elastin.
Diefenbach, Claudia, Hägglund, Per, Karsdal, Morten A., Kristensen, Jacob Hull, Oersnes-Leeming, Diana J., Sand, Jannie M. B., Svensson, Birte, Willumsen, Nicholas   +7 more
core   +1 more source

TGFβ (transforming growth factor-β) blockade induces a human-like disease in a nondissecting mouse model of abdominal aortic aneurysm [PDF]

, 2017
Objective-Current experimental models of abdominal aortic aneurysm (AAA) do not accurately reproduce the major features of human AAA. We hypothesized that blockade of TGF beta (transforming growth factor-beta) activity-a guardian of vascular integrity ...
Clément, Marc, Esposito, Bruno, Finigan, Alison, Lareyre, Fabien, Mallat, Ziad, Master, Leanne, Patel, Meghana, Pohlod, Stefanie, Raffort, Juliette, Stergiopulos, Nikolaos, Taleb, Soraya, Trachet, Bram, Vandestienne, Marie   +12 more
core   +2 more sources

Thermoelasticity of Elastin [PDF]

Nature, 1970
THERE is some controversy about the presence in elastin of an ordered structure1–3. Mammi et al.4 now report evidence for the occurrence of some degree of α-helix conformation in the native protein. The conformation was previously5 observed in soluble elastin; the temperature coefficient of the α-helix had different values in solvents such as water or ...
D, Volpin, A, Ciferri
openaire   +2 more sources