Results 21 to 30 of about 57,913 (262)

Mechanical Properties and Functions of Elastin: An Overview

Biomolecules, 2023
Human tissues must be elastic, much like other materials that work under continuous loads without losing functionality. The elasticity of tissues is provided by elastin, a unique protein of the extracellular matrix (ECM) of mammals.
Hanna Trębacz, Angelika Barzycka
doaj   +1 more source

Bioactive recombinant human elastin gel for reconstructing elastic fibers and rejuvenating endogenously aged skin

Materials Today Bio
Endogenous skin aging results in oxidative stress and degradation of elastic fibers, leading to reduced skin elasticity and dermal laxity. Current treatments rarely target elastic fiber regeneration.
Yi Yang, Wenjie Huang, Jingjing Shi, Bei Tian, Caihong Fu, Jianxi Xiao   +5 more
doaj   +1 more source

Elastin Structure, Synthesis, Regulatory Mechanism and Relationship With Cardiovascular Diseases

Frontiers in Cell and Developmental Biology, 2021
As the primary component of elastic fibers, elastin plays an important role in maintaining the elasticity and tensile ability of cardiovascular, pulmonary and many other tissues and organs.
Keke Wang, Xiangguang Meng, Zhikun Guo, Zhikun Guo   +3 more
doaj   +1 more source

Elastin in the Pathogenesis of Abdominal Aortic Aneurysm

Cells
Abdominal aortic aneurysms (AAAs) are progressive, life-threatening vascular disorders characterized by focal dilation of the abdominal aorta due to chronic weakening of the arterial wall.
Dunpeng Cai, Shi-You Chen
doaj   +1 more source

Elastin genetic point mutation and the risk of pelvic organ prolapse

Clinical and Experimental Obstetrics & Gynecology, 2020
Aim: A missense mutation in the elastin gene (g28197A > G) is associated with an increased risk for inguinal hernias. Due to the shared epidemiological and pathophysiological features between pelvic organ prolapse (POP) and inguinal hernias, the authors ...
N. Haya, I. Feferkorn, F. Fares, N. Azzam, R. Auslender, Y. Abramov   +5 more
doaj   +1 more source

Research on the expression of elastin in the conjoint fascial sheath for the correction of severe unilateral congenital blepharoptosis

BMC Ophthalmology, 2022
Background To investigate the expression of elastin in the conjoint facial sheath (CFS) in patients with severe unilateral congenital blepharoptosis in different age groups.
Zhaochuan Liu, Xin Jia, Runhui Pang, Huixing Wang, Junhu Shi, Ping Bai   +5 more
doaj   +1 more source

A novel method to fabricate elastin/collagen fiber composites: Proof of concept

Materials Letters: X
Collagen and elastin are the main fibrous proteins of load-bearing soft tissues, conferring extensibility and strength upon those tissues through their interactions.
Kosuke Shinokawa, Ayae Sugawara-Narutaki, Jeonghyun Kim, Takeo Matsumoto, Eijiro Maeda   +4 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Light‐Assisted 3D Printing Techniques and Photocrosslinking Strategies: Recent Advances in Musculoskeletal Tissue Engineering

Advanced Engineering Materials, EarlyView.
In this review, the current state of light‐assisted 3D printing as it pertains to engineering musculoskeletal tissues including bone, cartilage, skeletal muscle, tendon, and ligaments is summarized. Common printing techniques, photoreactive materials, and study design choices are compiled and reviewed.
Meagan Morgan, Bin Zhang, Roger Narayan
wiley   +1 more source

Presenilin-1 in smooth muscle cells facilitates hypermuscularization in elastin aortopathy

iScience
Summary: Smooth muscle cell (SMC) accumulation is central to the pathogenesis of elastin-defective arterial diseases, including supravalvular aortic stenosis (SVAS).
Junichi Saito, Jui M. Dave, Freddy Duarte Lau, Daniel M. Greif   +3 more
doaj   +1 more source