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Elastin in Diseases

open access: yesJournal of Investigative Dermatology, 1982
Previous morphologic observations have suggested abnormalities in the elastic fibers in a number of both inherited and acquired diseases. Recent progress made in understanding of the normal biology of elastin has allowed us to examine these diseases by biochemical means. In this review we are discussing the current status of the research on the elastin
Uitto, Jouni   +3 more
openaire   +2 more sources

Sterilization of lung matrices by supercritical carbon dioxide [PDF]

open access: yes, 2016
Lung engineering is a potential alternative to transplantation for patients with end-stage pulmonary failure. Two challenges critical to the successful development of an engineered lung developed from a decellularized scaffold include (i) the suppression
Balestrini, Jenna L   +10 more
core   +2 more sources

Regional biomechanical and histological characterisation of the passive porcine urinary bladder: Implications for augmentation and tissue engineering strategies [PDF]

open access: yes, 2009
The aim of this study was to identify and quantify potential regional and directional variations in the quasistatic uniaxial mechanical properties of the passive urinary bladder wall.
Bolland, Fiona   +4 more
core   +1 more source

In-situ formed elastin-based hydrogels enhance wound healing via promoting innate immune cells recruitment and angiogenesis

open access: yesMaterials Today Bio, 2022
Harnessing the inflammation and angiogenesis is extremely important in wound healing. In this study, we developed bioactive elastin-based hydrogels which can recruit and modulate the innate immune cells and accelerate angiogenesis in the wound site and ...
Duo-Mei Tian   +19 more
doaj   +1 more source

Mechanical Properties and Functions of Elastin: An Overview

open access: yesBiomolecules, 2023
Human tissues must be elastic, much like other materials that work under continuous loads without losing functionality. The elasticity of tissues is provided by elastin, a unique protein of the extracellular matrix (ECM) of mammals.
Hanna Trębacz, Angelika Barzycka
doaj   +1 more source

The Impact of Vein Mechanical Compliance on Arteriovenous Fistula Outcomes [PDF]

open access: yes, 2016
© 2016 Elsevier Inc. Background Arteriovenous fistulae (AVFs) are the preferred access for hemodialysis but suffer a high early failure rate. The aim of this study was to determine how venous distensibility, as measured in vitro, relates to early ...
Barnes, Rachel   +4 more
core   +2 more sources

Elastin peptides signaling relies on neuraminidase-1-dependent lactosylceramide generation. [PDF]

open access: yesPLoS ONE, 2010
The sialidase activity of neuraminidase-1 (Neu-1) is responsible for ERK 1/2 pathway activation following binding of elastin peptide on the elastin receptor complex.
Anthony Rusciani   +9 more
doaj   +1 more source

Biomechanical and biochemical properties of the thoracic aorta in warmblood horses, Friesian horses, and Friesians with aortic rupture [PDF]

open access: yes, 2015
Background: Thoracic aortic rupture and aortopulmonary fistulation are rare conditions in horses. It mainly affects Friesian horses. Intrinsic differences in biomechanical properties of the aortic wall might predispose this breed.
Chiers, Koen   +10 more
core   +2 more sources

Elastin Structure, Synthesis, Regulatory Mechanism and Relationship With Cardiovascular Diseases

open access: yesFrontiers in Cell and Developmental Biology, 2021
As the primary component of elastic fibers, elastin plays an important role in maintaining the elasticity and tensile ability of cardiovascular, pulmonary and many other tissues and organs.
Keke Wang   +3 more
doaj   +1 more source

Artificial Extracellular Matrix Proteins Containing Phenylalanine Analogues Biosynthesized in Bacteria Using T7 Expression System and the PEGylation [PDF]

open access: yes, 2011
In vivo incorporation of phenylalanine (Phe) analogues into an artificial extracellular matrix protein (aECM-CS5-ELF) was accomplished using a bacterial expression host that harbors the mutant phenylalanyl-tRNA synthetase (PheRS) with an enlarged binding
Furukawa, Yuya   +6 more
core   +2 more sources

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