Results 151 to 160 of about 13,438 (200)
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Circulating elastin peptides, role in vascular pathology
Pathologie Et Biologie, 2014The atherosclerotic process starts with the degradation of elastic fibers. Their presence was demonstrated in the circulation as well as several of their biological properties elucidated. We described years ago a procedure to obtain large elastin peptides by organo-alkaline hydrolysis, κ-elastin.
J Labat-Robert
exaly +3 more sources
Effect of age on the vasodilatory action of elastin peptides
Mechanisms of Ageing and Development, 1997We have recently shown, on young adult rat aorta rings, that elastin peptides induce a dose and endothelium-dependent vasodilation mediated by the 67 kDa subunit of the high affinity elastin-laminin receptor and, at least in part, by EDRF (NO).
G Faury
exaly +3 more sources
Elastin Peptides: The Components of a Partial Alkaline Hydrolyzate of Elastin
Connective Tissue Research, 1973Bovine ligamentum nuchae elastin was partially hydrolyzed by ethanolic KOH. Fractionation of the dialyzed product on a column of SE-Sephadex yielded eight fractions which were characterized by amino acid analysis as well as hexose and lipid contents. The approximate molecular weight or size range of each of the fractions was determined by Sephadex gel ...
S, Keller, I, Mandl
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Isolation of two peptides from elastin
Biochimica et Biophysica Acta (BBA) - Protein Structure, 1974Abstract Two fractions have been isolated from extracts obtained by the autoclave treatment of purified elastin from bovine ligaments. One fraction contains a very low proportion of polar amino acids and no cross-links. The second fraction is relatively rich in polar amino acids and in lysinonorleucine.
I, Castellani, D, Volpin
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Effect of Elastin Peptides on Vascular Tone
Journal of Vascular Research, 2008Elastin peptides are present in human blood. As elastin receptors exist on several cell types, especially endothelial cells, this investigation was carried out to study the effect of elastin peptides on vascular tone. For this purpose, rat aortic rings were mounted in an organ bath for isometric tension measurements.
G, Faury +4 more
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Guanidination of the Lysine Residues Present in Fibrous Elastin and in Soluble Elastin Peptides
Connective Tissue Research, 1981We have found that only 20 to 30% of the lysine residues measured after acid hydrolysis of insoluble elastin and alpha-elastin were blocked by prior guanidination of elastin with o-methylisourea. In contrast free lysine was guanidinated almost 100% and a purified, highly crosslinked peptide fraction of low molecular weight, 85%.
M, Guay, F, Lamy
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ANTIGENICITY OF HUMAN LUNG ELASTIN PEPTIDES
1981Antigenic determinants of human lung elastin peptides were studied by fractionation on an SE-Sephadex C-50 column. By elution profile, tubes were pooled into 12 fractions. Amino acid analysis of these fractions showed that the first seven contained mostly non-polar peptides which lacked desmosine and isodesmosine residues.
G M, Turino +3 more
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Structural characterization of VGVAPG, an elastin‐derived peptide
Peptide Science, 2004AbstractElastic fibers are an important component of the extracellular matrix, providing elasticity and resilience to tissues that require the ability to deform repetitively and reversibly. Among the elastin‐derived peptides, the Val–Gly–Val–Ala–Pro–Gly (VGVAPG) hexapeptide is known for its chemotactic activity and metalloproteinases upregulation ...
Nicolas, Floquet +5 more
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Antigenic Determinants in Human Lung Elastin Peptides
Connective Tissue Research, 1980Elastin peptides were fractionated on a SE-Sephadex C-50 column by sequential elution with the following buffers: a) 0. 01 N acetic acid, b) linear gradient from 0. 05 N sodium acetate buffer, pH 4. 0 to 0. 4 N sodium acetate buffer, pH 4. 6, c) 0. 4 N sodium acetate buffer, pH 4. 6, d) 0. 5 N sodium hydroxide.
T V, Darnule +4 more
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