Comparison of Efficacy and Safety of Denosumab with Eldecalcitol or Native Vitamin D in Postmenopausal Chinese Women with Osteoporosis (ESCORT): A Randomized Controlled Trial. [PDF]
Zeng Y +8 more
europepmc +1 more source
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
IL-33 serum levels are elevated in ELD mice.
Serum levels of (A) total IgE, (B) parasite-specific IgE, (C) IL-33, and (D) IL-4 ten days after the MF challenge in naïve, MF-only challenged, ELD and dblGATA ELD mice. (E) DNA quantification of 20 μl BAL fluid of MF-challenged, ELD and dblGATA ELD mice.
Joséphine Gal (14000010) +11 more
core +1 more source
Significant resolution of multiple adult-onset xanthogranulomas with MEK inhibitor therapy. [PDF]
Wang X +5 more
europepmc +1 more source
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Comprehend to Comprehension: Teaching Nominalization to Secondary ELD Teachers
Research Question. What happens when ELD teachers learn about nominalization as it is used in academic texts? Subquestions. (1) What understandings do ELD teachers currently have of nominalization, and how did they acquire the knowledge they have?
Cameron, Janelle Shara
core
Dosage-Associated Maternal Dominance and Tissue-Specific Paternal Expression in a Triploid Hybrid Between Grass Carp and Yellowcheek. [PDF]
Chang S +10 more
europepmc +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Speed of clinical response to external lumbar drainage as a predictor of outcome of ventriculoperitoneal shunt in normal pressure hydrocephalus: A prospective cohort study. [PDF]
Bhuiyan MS, Hoque UA.
europepmc +1 more source
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source

