Results 141 to 150 of about 29,969 (357)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Economic of Land Degradation in Centra Asia_Newsletter, #2, 7 August 2015

open access: yes, 2016
In this issue: ELD CA National teams defined and visited pilot research sites. ELD CA Initiative presented at the International Water Forum of Mountain Countries. ELD CA National teams defined ecosystem services and their valuation methods.
Guchgeldiyeg, Oleg
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Heart Rate Following Short-Term Beta-Blocker Titration Predicts All-Cause Mortality in Elderly Chronic Heart Failure Patients: Insights from the CIBIS-ELD Trial [PDF]

open access: bronze, 2014
Hans‐Dirk Düngen   +13 more
openalex   +1 more source

Використання r-алгоритму для розв’язання квадратичної ELD-задачі

open access: yes, 2017
Розглядається r(α) -алгоритм з адаптивним кроком. Його програмна реалізація на мові octave застосована для розв'язання задачі оптимального добового завантаження енергосистеми (ELD-задача). Описано результати обчислювального експерименту для енергосистеми
Фесюк, О.В., Стецюк, П.І.
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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