Results 51 to 60 of about 786,116 (247)

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Human dental pulp stem cells attenuate airway inflammation in mice with PM2.5-induced asthma exacerbation by inhibiting the pyroptosis pathway

Stem Cell Research & Therapy
Background Fine particulate matter (PM2.5) exposure significantly exacerbates respiratory morbidity, particularly in asthmatic individuals, highlighting an urgent need for effective therapeutic interventions.
Jianling Liu, Yuehua Chen, Zhongpeng Li, Zhangwen Li, Fengjuan Lyu, Fang Wang, Aili Wang, Zhangquan Liu, Xiaoyang Liao, Jian Wu   +9 more
doaj   +1 more source

Efficacy and Tolerability of Topotecan/Cyclophosphamide/Dinutuximab in Relapsed and Refractory High‐Risk Neuroblastoma: A Multi‐Institutional Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Chemoimmunotherapy with irinotecan, temozolomide, and dinutuximab (I/T/DIN) has emerged as first‐line therapy for relapsed/refractory (r/r) high‐risk neuroblastoma (HRNB) in North America. Topotecan and cyclophosphamide (T/C) are often used in combination with dinutuximab in the setting of lack of response, progression, or incomplete ...
Benjamin J. Lerman, Madeleine King, Rajen Mody, Sara‐Jane Onyeama, Araz Marachelian, Thomas Cash, Sara M. Federico, Meaghan Granger, Ami V. Desai, Suzanne Shusterman, Jennifer H. Foster, Elizabeth Sokol, Chelsee Greer, Keri Streby, Holly J. Meany, Kieuhoa T. Vo, Margaret E. Macy, Rochelle Bagatell   +17 more
wiley   +1 more source

Psychometric Development of the Thai Version of Geriatric Care Competency in Significant Diseases Among Caregivers in a Rural Thai Community

SAGE Open Nursing
Background A review of the literature on geriatric care assessment tools revealed no specific tools for assessing caregivers’ abilities in terms of seven major diseases—acute myocardial infarction, stroke, falls, diabetes, hypertension, osteoarthritis ...
Praditporn Pongtriang, Pilaiporn Sukcharoen, Aranya Rakhab, Vasinee Somsiri, Apinya Ingard   +4 more
doaj   +1 more source

Referral rates for children with acute gastroenteritis: a retrospective cohort study

BJGP Open, 2020
Background: Hospital admission rates are increasing for children with acute gastroenteritis. However, it is unknown whether this increase is accompanied by an increase in referral rates from GPs due to increased workloads in primary care out-of-hours ...
Pien Ingrid Wolters, Gea Holtman, Freek Fickweiler, Irma Bonvanie, Anouk Weghorst, Johan Post, Boudewijn Kollen, Marjolein Berger   +7 more
doaj   +1 more source

Factors associated with fall risk of community-dwelling older people: A decision tree analysis

Digital Health, 2023
Objective To examine the predictive attributes for accidental falls in community-dwelling older people in Hong Kong using decision tree analysis. Methods We recruited 1151 participants with an average age of 74.8 years by convenience sampling from a ...
Kenneth N K Fong, Raymond C K Chung, Patrick P C Sze, Carmen K M NG   +3 more
doaj   +1 more source

Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy, Elizabeth L. Seashore, W. Susan Cheng, Shondra Clay, Jessica A. Casas, Jennifer H. Foster   +5 more
wiley   +1 more source

Stroke in the Setting of Giant Cell Arteritis: A Case Report

Case Reports in Medicine, 2010
We describe an unusual complication of a common disease: stroke presenting in a man recently diagnosed with polymyalgia rheumatica. Initial inflammatory markers were misleading. We discuss pitfalls in diagnosis, and approach to management.
S. McDermott, N. Casey, D. J. Robinson, K. M. Tan   +3 more
doaj   +1 more source

Molecular Methods for Rare Hemoglobinopathy Cases: First Brazilian Report of Pediatric Siblings with Hb O‐Arab and Alpha‐Thalassemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hemoglobinopathies are prevalent globally; diagnosis is complex in high genetic admixture populations like Brazil. We report, in two pediatric siblings, the first documented cases in Brazil of heterozygosity for hemoglobin (Hb) O‐Arab with coinheritance of α‐thalassemia (αα/−α4.2; −α3.7/−α4.2), resulting in microcytic and hypochromic anemia ...
Elisângela de Souza Miranda Muynarsk, Amanda Cristina Meneguetti Berti, Bárbara Braga Vieira Marques, Victoria Simões Bernardo, Flaviene Felix Torres, Ingrid Souza Dias, Vanessa da Silveira Ramos de Castro, Gabriela Alves Bernardino, Danilo Grünig Humberto da Silva, Edis Belini‐Júnior   +9 more
wiley   +1 more source

The Effect of Melilotous Officinalis Oil on the Physical Function of Older Adults With Mild to Moderate Knee Osteoarthritis: A Double-Blind Randomized Controlled Trial

Sālmand, 2019
Objectives: Osteoarthritis (OA) is one of the most common diseases among older people that although does not directly lead to mortality, is one the leading causes of disability in older people.
Gholamreza Ansari, Ahmad Delbari, Mehrdad Karimi, Ahmad Ali Akbari Kamrani, Yadollah Abolfathi Momtaz, seyran mohamadi, Robab Sahaf   +6 more
doaj