Results 231 to 240 of about 1,481,214 (358)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Delirium upon admission to Swiss nursing homes: a cross-sectional study

Swiss Medical Weekly, 2010
Swiss Medical Weekly
doaj   +1 more source

What are the current best practices for managing acute myocardial infarction in elderly patients?

Tripdatabase
openalex   +1 more source

To Fix or Not to Fix: Management of Distal Radial Fractures in Elderly Patients

, 2019
Tamara D. Rozental
openalex   +2 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Representative MRI findings in elderly patients with cryptococcal meningitis.

Xiaofeng Xu (103084), Xiaohong Su (451978), Weipeng Li (1492822), Li Xu (108702), Dongcheng Li (12444797), Kai Dai (4685950), Junyu Liu (479315), Jia Liu (41593), Fuhua Peng (326511), Ying Jiang (5910)   +9 more
openalex   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Conservative Kidney Management in Elderly Patients Not Receiving Dialysis: How to Proceed? [PDF]

Kidney360
Al-Muhaiteeb A.
europepmc   +1 more source

Effect of Positive Mental Health on Elderly Patients with Chronic Diseases: The Chain-Mediated Effects of Gratitude and Forgiveness Tendencies at a Tertiary Hospital in Guangzhou

HuanZhong Liu, Zhou Ying, Chun-Qin Liu, Xiaobing Wu, Graeme D Smith, Thomas Wong, Xinyang Hu, Yue Liu, Yin-he Qin, Wenjing Wang   +9 more
openalex   +1 more source

Age versus American society of anesthesiologists – Examining 30-day mortality and morbidity in elderly patients undergoing colectomy from the American college of surgeons national surgical quality improvement program

, 2019
AmyK Wise, AnneK Mongiu, RowzaT Rumma, Russellw Farmer   +3 more
openalex   +1 more source