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Eleanor Roosevelt in Montreal [PDF]

open access: yesJournal of Transnational American Studies, 2018
This article discusses First Lady Eleanor Roosevelt’s international travels during the Second World War. Mrs. Roosevelt achieved her greatest renown in the postwar period as a champion of international human rights, notably in her role as chair of the ...
Greg Robinson
doaj   +4 more sources

The CRISPR-Cas9 crADSL HeLa transcriptome: A first step in establishing a model for ADSL deficiency and SAICAR accumulation [PDF]

open access: yesMolecular Genetics and Metabolism Reports, 2019
Adenylosuccinate lyase (ADSL) catalyzes two steps in de novo purine synthesis (DNPS). Mutations in ADSL can result in inborn errors of metabolism characterized by developmental delay and disorder phenotypes, with no effective treatment options. Recently,
Randall C. Mazzarino   +6 more
doaj   +2 more sources

Eleanor Roosevelt, the United Nations and the Role of Radio Communications [PDF]

open access: yesAthens Journal of Mass Media and Communications, 2016
Eleanor Roosevelt communicated with the public through a variety of media, both before, during and following her time in the White House. In 1946 she became part of the US delegation to the newly formed United Nations and she used newspaper columns ...
Anya Luscombe
doaj   +1 more source

«Poverty is an expensive luxury. We cannot afford it»: Eleanor Roosevelt e l’America della Great Depression

open access: yesStoria delle Donne, 2018
The essay would like to emphasize the role played by Eleanor Roosevelt in the effort to solve the economic crisis following the collapse of Wall Street Stock Exchange in 1929. More specifically, Eleanor Roosevelt challenged the administration in order to
Raffaella Baritono
doaj   +1 more source

Effects of specific inhibition of sterol biosynthesis on the uptake and utilization of low density lipoprotein cholesterol by HepG2 cells.

open access: yesJournal of Lipid Research, 1991
Treatment of HepG2 cells in lipoprotein-deficient media with 4,4,10 beta-trimethyl-trans-decal-3 beta-ol (TMD) abolished the incorporation of [3H]acetate into cholesterol with concomitant accumulation of squalene 2,3(S)-oxide and squalene 2,3(S):22(S),23-
SR Panini, GT Everson, TA Spencer
doaj   +1 more source

Endogenous sterol synthesis is not required for regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase by low density lipoprotein

open access: yesJournal of Lipid Research, 1987
It has been proposed that an endogenously synthesized oxysterol mediates the regulation of cholesterol biosynthesis by low density lipoprotein in cultured mammalian cells.
E Burki, J Logel, M Sinensky
doaj   +1 more source

Thirty-Two Teeth, Thirty-Two Challenges: Memoirs of a Dentist Turned Policy Maker

open access: yesNigerian Dental Journal, 2023
According to Eleanor Roosevelt, “memoirs are only useful as the lives you read about and analyse may suggest to you something that you may find useful in your own journey through life.” I am therefore glad to state that I see myself quite relevant to ...
Adebimpe Adebiyi
doaj   +1 more source

Pauli Murray: Human Rights Visionary and Trailblazer

open access: yesAJIL Unbound, 2023
While other scholars have discussed Dr. Pauli Murray's remarkable contributions to race and sex equality law,1 few, if any, have placed her contributions within the context of the broader tradition of human rights law.
Darin E. W. Johnson, Catherine Powell
doaj   +1 more source

Reduced purine biosynthesis in humans after their divergence from Neandertals

open access: yeseLife, 2021
We analyze the metabolomes of humans, chimpanzees, and macaques in muscle, kidney and three different regions of the brain. Although several compounds in amino acid metabolism occur at either higher or lower concentrations in humans than in the other ...
Vita Stepanova   +25 more
doaj   +1 more source

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