Results 101 to 110 of about 1,895,713 (296)

Charge‐Reversed Lipid Nanoparticles Enable Encapsulation of Pt2L4 Nanocages for In vivo Anti‐Cancer Treatment

Advanced Materials, EarlyView.
Charge‐reversed lipid nanoparticles (revLNPs) enable efficient encapsulation and delivery of cationic Pt2L4 nanocages. Encapsulation preserves potent anticancer activity while improving circulation, reducing vascular leakage, and promoting favorable biodistribution in vivo.
Renzo A. Knol, Bochuan Hu, Eduard O. Bobylev, Martina Farber, Petrus C. M. Laan, Thomas J. F. Kock, Bauke Fontein, Johanna Erbani, Oscar Escalona‐Rayo, Seline S. Roose, Tom Keijer, Gabriel Forn‐Cuní, B. Ewa Snaar‐Jagalska, Leila Akkari, Joost N. H. Reek, Alexander Kros, Dennis Aschmann   +16 more
wiley   +1 more source

Turning Nd‐Fe‐B Swarf Into High‐Value Bulk Feedstocks via Sustainable Hydrogen Plasma: From Rare‐Earth Oxides to Metals and Hydrides

Advanced Materials, EarlyView.
Oxidized Nd‐Fe‐B magnet swarf is transformed into valuable bulk feedstock through a single‐step hydrogen plasma process. The reaction converts complex rare‐earth‐containing waste into separated metallic, oxide, and hydride fractions without acid leaching.
Naritai Chimed, Oliver Diehl, Ömer K. Büyükuslu, J. Manoj Prabhakar, Dennis Klapproth, Patricia Jovičević‐Klug, Jürgen Gassmann, Dierk Raabe, Tim M. Schwarz, Matic Jovičević‐Klug   +9 more
wiley   +1 more source

Bacteria‐Trained, MnO2‐Armored Dendritic Cells for Immunotherapy

Advanced Materials, EarlyView.
MnO2‐armored, bacteria‐trained dendritic cells undergo tumor‐responsive mechanical and immunological transformation. The nanocoating masks immune ligands and maintains a mechanically stiff, quiescent state during circulation, while the tumor microenvironment removes the armor and restores cellular deformability and immune accessibility.
Zhao Guo, Min Ge, Zesong Ruan, Tingwang Shi, Mahyar Mahmoudi, Soohwan An, Na Kong, Yunfeng Chen, Han Lin, Wei Tao   +9 more
wiley   +1 more source

Biomass DNA: An Emerging Building Block for Advanced Materials

Advanced Materials, EarlyView.
Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley   +1 more source

Criterion Circle-Optimized Hybrid Finite Element–Statistical Energy Analysis Modeling with Point Connection Updating for Acoustic Package Design in Electric Vehicles

World Electric Vehicle Journal
This research is based on the acoustic package design of new energy vehicles, investigating the application of the hybrid Finite Element–Statistical Energy Analysis (FE-SEA) model in predicting the high-frequency dynamic response of automotive structures,
Jiahui Li, Ti Wu, Jintao Su
doaj   +1 more source

Electronic Stability Control for Improving Stability for an Eight In-Wheel Motor-Independent Drive Electric Vehicle

Shock and Vibration, 2019
An electronic stability control (ESC) based on torque distribution is proposed for an eight in-wheel motor-independent drive electric vehicle (8WIDEV).
Yu Zhao, Chengning Zhang
doaj   +1 more source

GaSex Nanoparticles Modulate Neutrophil Function and Mitigate NET‐Driven Osteogenic Impairment in Osteomyelitis Therapy

Advanced Materials, EarlyView.
Neutrophil extracellular traps (NETs) emerge as a critical repair‐limiting factor in osteomyelitis, driving osteoblast mitochondrial dysfunction and excessive PINK1/Parkin‐mediated mitophagy. Gallium–selenium nanoparticles (GaSex) scavenge reactive oxygen species, redirect neutrophils from NETosis toward bactericidal phagocytosis, eliminate methicillin‐
Kai Ye, Xuanzhe Liu, Zifan Pei, Chenyi Jiang, Xiaofen Zhang, Lin Lin, Qihang Fang, Binyu Chen, Longxiang Shen, Liang Cheng, Peng Ding, Xianyou Zheng   +11 more
wiley   +1 more source

A Retinal Matrix Stiffening Model Reveals FAK‐Dependent Mechanotransduction in Pericytes Underlies Vascular Destabilization

Advanced Materials, EarlyView.
In this study, we show that retinal matrix stiffness is increased in diabetic mice. Using engineered human vascular models with controlled matrix stiffness, we demonstrate that stiffening activates focal adhesion kinase (FAK) signaling in pericytes, suppresses Notch signaling, and disrupts vascular morphology.
Emily Warren, Alex Wu, Lucas Ramirez, Yaqing Huang, Connor Amelung, Sophia Saxonhouse, Sharon Gerecht   +6 more
wiley   +1 more source

A Noninvasive Approach to Study Localized Forces in 3D Epithelia

Advanced Materials, EarlyView.
Epithelial morphogenesis depends on dynamic mechanical coupling between adhesion complexes and the cytoskeleton, yet its regulation in polarized 3D tissues remains elusive. We developed a noninvasive strategy using cell‐like elastic microbeads to quantify local forces in intact epithelia.
Niels Gouirand, Muhamet Ibrahimi, Claire Valotteau, Brice Lecouffe, André Le Bivic, Dominique Massey‐Harroche, Felix Rico, Matthias Merkel, Delphine Delacour, Elsa Bazellières   +9 more
wiley   +1 more source

The Development of a Data-Driven Surrogate Model for Enhancing Electric Vehicle Cabin Airflow Analysis

Fluids
This paper presents a data-driven surrogate model for predicting cabin airflow and its integration into system-level electric vehicle simulations for energy management analysis.
Mirza Popovac, Thomas Bäuml, Dominik Dvorak, Dragan Šimić   +3 more
doaj   +1 more source