Results 81 to 90 of about 641,944 (348)

Reconfigurable Nucleic Acid Nanoparticles with Therapeutic RNAi Responses to Intracellular Disease Markers

open access: yesAdvanced Functional Materials, EarlyView.
Many known diseases arise from dysregulated gene expression, and differentially expressed genes can serve as biomarkers to distinguish diseased cells from healthy tissues. In this study, reconfigurable nucleic acid nanoparticles (recNANPs) are introduced that can detect overexpressed cancer biomarkers and subsequently release RNAi inducers to silence ...
Yelixza I. Avila   +7 more
wiley   +1 more source

Baseline tests of the battronic Minivan electric delivery van [PDF]

open access: yes
An electric passenger vehicle was tested to develop data characterizing the state of the art of electric and hybrid vehicles. The test measured vehicle maximum speed, range at constant speed, range over stop-and-go driving schedules, maximum acceleration,
Bozek, J. M.   +3 more
core   +1 more source

Synergistic Osteogenesis After Co‐Administration of cmRNAs Encoding BMP‐2 and BMP‐7 Utilizing a Transcript‐Activated Matrix

open access: yesAdvanced Functional Materials, EarlyView.
This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer   +7 more
wiley   +1 more source

Steady-State Model Enabled Dynamic PEMFC Performance Degradation Prediction via Recurrent Neural Network

open access: yesEnergies
Proton exchange membrane fuel cells (PEMFC), distinguished by rapid refueling capability and zero tailpipe emissions, have emerged as a transformative energy conversion technology for automotive applications.
Qiang Liu   +5 more
doaj   +1 more source

Review: Characterization and Modeling of the Mechanical Properties of Lithium-Ion Batteries

open access: yesEnergies, 2017
Li-ion batteries have become a dominant power source in consumer electronics and vehicular applications. The mobile use of batteries subjects them to various mechanical loads.
Golriz Kermani, Elham Sahraei
doaj   +1 more source

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

open access: yesAdvanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen   +30 more
wiley   +1 more source

Commercial Sodium‐Ion Batteries: Understanding Mechanism and Function Using In Operando Neutron Diffraction and X‐Ray Tomography Studies

open access: yesAdvanced Functional Materials, EarlyView.
In operando neutron diffraction reveals the real‐time structural evolution of O3‐type NaxNi1/3Mn1/3Fe1/3O2 in commercial sodium‐ion batteries that is coupled with electrochemical and tomography data. The study establishes a direct link between current‐dependent phase transitions, lattice kinetics, and electrochemical behavior, offering mechanistic ...
B. D. K. K. Thilakarathna   +4 more
wiley   +1 more source

Classifying electric vehicle adopters and forecasting progress to full adoption

open access: yesnpj Sustainable Mobility and Transport
Electric light-duty vehicle sales are increasing, but adoption is not uniform. Forecasting who is adopting and when is crucial to planning infrastructure, creating incentives, and ensuring equity. We identify different clusters of adopters in California,
Trisha V. Ramadoss   +4 more
doaj   +1 more source

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