Results 41 to 50 of about 9,959 (213)

Envelope enhancement increases cortical sensitivity to interaural envelope delays with acoustic and electric hearing. [PDF]

PLoS ONE, 2014
Evidence from human psychophysical and animal electrophysiological studies suggests that sensitivity to interaural time delay (ITD) in the modulating envelope of a high-frequency carrier can be enhanced using half-wave rectified stimuli.
Douglas E H Hartley, Amal Isaiah
doaj   +1 more source

Electrical Dipole Magnitudes of Auditory Brainstem Responses.

AUDIOLOGY JAPAN, 1993
ABRのI波およびV波について電流双極子のベクトル成分を求め, その臨床的有用性を検討した。 I波・V波とも双極子のベクトルの大きさにはかなり大きな個体差がみられ, 今回用いた方法では臨床応用にはまだ問題があるものと思われた。 I波においては刺激音圧が90から60dBnHLまでは音圧の減少とともに著しくベクトルの大きさが減少したが, 刺激音圧60dBnHL以下ではベクトルの大きさの変化はゆるやかであり, これは蝸電図APのH曲線とL曲線に対応するものとも考えられた。 また刺激音圧を減少させると, I波のベクトルの大きさの減少の方がV波のベクトルの減少より著明で, これは神経パルスの同期性と関連した現象とも推測された。
openaire   +2 more sources

Ten-year follow-up of auditory brainstem implants: From intra-operative electrical auditory brainstem responses to perceptual results

PLOS ONE, 2023
The auditory brainstem implant (ABI) can provide hearing sensation to individuals where the auditory nerve is damaged. However, patient outcomes with the ABI are typically much poorer than those for cochlear implant recipients. A major limitation to ABI outcomes is the number of implanted electrodes that can produce auditory responses to electric ...
Veronese, Sheila, Cambiaghi, Marco, Tommasi, Nicola, Sbarbati, Andrea, Galvin, John J   +4 more
openaire   +4 more sources

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

Advanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang, Na Li, Yan Wang, Jing Zhang, Jiahui Liu, Lei Chen, Yongdong Song, Yurong Mu, Yuechen Han, Yafeng Lyu, Xiaofei Li, Hanyue Wang, Jing Wang, Yao Lu, Zhaomin Fan, Daogong Zhang, Haibo Wang   +16 more
wiley   +1 more source

Transforming Brain Health With Neurotechnology Convergence (Part II): Intelligent Neurointervention Systems for Neurological Disorders

Brain Health, EarlyView.
ABSTRACT Neurological disorders represent a critical domain within global health, necessitating advanced interventions to address complex pathologies such as tumors, functional disorders, and cerebrovascular diseases. Despite the proven benefits of early intervention, current treatment paradigms face significant challenges: (1) limited precision in ...
Qing Ye, Fei Peng, Chao Pan, Ping Zhang, Xuewei Xie, Zixiao Li, Yingxin Tang, Danyang Chen, Yuanwei Li, Jiawen Wu, Zao Han, Qing Dai, Quansheng Gu, Jizong Zhao, Zhouping Tang   +14 more
wiley   +1 more source

Brain–Computer Interfaces: The Dawn of a New Era in Disease Treatment

Exploration, EarlyView.
This study investigates the potential of brain–computer interface (BCI) technology in treating neuropsychiatric disorders, such as movement and communication barriers. Our review examines the history, signal paradigms, and diverse applications of BCI while also discussing ongoing research into novel materials and emerging technologies that offer ...
Yuqi Feng, Wangzheqi Zhang, Jun Chen, Huang Wu, Lei Wu, Yanhao Qiu, Xiaoming Deng, Chenglong Zhu, Yisheng Chen, Zhijie Zhao, Changli Wang, Xiaomin Zhang   +11 more
wiley   +1 more source

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, EarlyView.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

The auditory brainstem response in hearing and deaf cats evoked by intracochlear electrical stimulation [PDF]

, 1983
This is a paper presented at a symposium on the Mechanisms of Hearing, held at Monash University, Melbourne, Australia from August 23-27, 1983. This version is reproduced with the permission of Monash University Press.This study was performed to ...
O'Leary, S. J., Clark, Graeme M., Walters, C., Black, R. C.   +3 more
core  

Developing Fast, Red-Light Optogenetic Stimulation of Spiral Ganglion Neurons for Future Optical Cochlear Implants

Frontiers in Molecular Neuroscience, 2021
Optogenetic stimulation of type I spiral ganglion neurons (SGNs) promises an alternative to the electrical stimulation by current cochlear implants (CIs) for improved hearing restoration by future optical CIs (oCIs).
Antoine Tarquin Huet, Antoine Tarquin Huet, Tobias Dombrowski, Tobias Dombrowski, Tobias Dombrowski, Vladan Rankovic, Vladan Rankovic, Vladan Rankovic, Anupriya Thirumalai, Anupriya Thirumalai, Tobias Moser, Tobias Moser, Tobias Moser, Tobias Moser   +13 more
doaj   +1 more source

Predicting cochlear structural alterations from auditory function in age‐related hearing loss mice based on optical coherence tomography

Journal of Intelligent Medicine, EarlyView.
Abstract With global population aging, age‐related hearing loss has become a major public health concern. Understanding the relationship between auditory functional decline and cochlear structural degeneration is essential for early detection and precise intervention.
Shu Zheng, Zhiqi Li, Junyue Wang, Guangjian Ni   +3 more
wiley   +1 more source