Results 61 to 70 of about 9,404 (188)

Effects of antioxidants on auditory nerve function and survival in deafened guinea pigs

Neurobiology of Disease, 2007
Based on in vitro studies, it is hypothesized that neurotrophic factor deprivation following deafferentation elicits an oxidative state change in the deafferented neuron and the formation of free radicals that then signal cell death pathways.
Jun Maruyama, Takahiko Yamagata, Mats Ulfendahl, Göran Bredberg, Richard A. Altschuler, Josef M. Miller   +5 more
doaj   +1 more source

The sympathoregulatory region of the mouse rostral brainstem relies on both GABA and glycine to generate inhibitory currents

The Journal of Physiology, EarlyView.
Abstract figure legend Our study demonstrates that both GABA and glycine mediate inhibitory postsynaptic currents in the ventrolateral/ventromedial medulla (VLM/VMM) and increasing the activity of inhibitory synapses facilitates glycine release. We found that presympathetic VLM/VMM neurons receive glycinergic inputs, which release both glycine and GABA,
Hong Gao, Lucie D. Desmoulins, Adrien J. R. Molinas, Courtney M. Dugas, Andrea Zsombok, Andrei V. Derbenev   +5 more
wiley   +1 more source

Resistance training tempo selectively modulates corticospinal and reticulospinal excitability in humans

The Journal of Physiology, EarlyView.
Abstract figure legend Three weeks of unilateral resistance training (RT) performed under metronome‐paced (MP‐RT) or self‐paced (SP‐RT) conditions increased strength (maximum voluntary force (MVF) and one‐repetition maximum (1RM)) but were accompanied by distinct neural adaptations.
Yonas Akalu, Jamie Tallent, Ashlyn K. Frazer, Ummatul Siddique, Mohamad Rostami, Glyn Howatson, Simon Walker, Dawson J. Kidgell   +7 more
wiley   +1 more source

A full-custom fully implantable cochlear implant system validated in vivo with an animal model

Communications Engineering
Realizations of fully implantable cochlear implants (FICIs) for providing adequate solution to esthetic concerns and frequent battery replacement have lacked of addressing system level criteria as a complete device.
Hasan Uluşan, M. Berat Yüksel, Özlem Topçu, H. Andaç Yiğit, Akın M. Yılmaz, Mert Doğan, Nagihan Gülhan Yasar, İbrahim Kuyumcu, Aykan Batu, Nebil Göksu, M. Birol Uğur, Haluk Külah   +11 more
doaj   +1 more source

Signaled two-way avoidance learning using electrical stimulation of the inferior colliculus as negative reinforcement: effects of visual and auditory cues as warning stimuli

Brazilian Journal of Medical and Biological Research, 1998
The inferior colliculus is a primary relay for the processing of auditory information in the brainstem. The inferior colliculus is also part of the so-called brain aversion system as animals learn to switch off the electrical stimulation of this ...
A.C. Troncoso, G. Cirilo-Júnior, G. Sandner, M.L. Brandão   +3 more
doaj   +1 more source

Cortical responses to balance perturbations persist without active postural control

The Journal of Physiology, EarlyView.
Abstract figure legend A robotic balance simulator was used to test whether cortical responses to balance perturbations are contingent on active balance control or instead reflect the detection of unexpected motion. Participants experienced identical support‐surface rotations (toes‐up and toes‐down) while actively controlling balance or while being ...
Daphne N. R. Jansen, Lucas Mensink, Matto Leeuwis, Patrick A. Forbes   +3 more
wiley   +1 more source

Auditory Rehabilitation in Rhesus Macaque Monkeys (Macaca mulatta) with Auditory Brainstem Implants

Chinese Medical Journal, 2015
Background: The auditory brainstem implants (ABIs) have been used to treat deafness for patients with neurofibromatosis Type 2 and nontumor patients. The lack of an appropriate animal model has limited the study of improving hearing rehabilitation by the
Zhen-Min Wang, Zhi-Jun Yang, Fu Zhao, Bo Wang, Xing-Chao Wang, Pei-Ran Qu, Pi-Nan Liu   +6 more
doaj   +1 more source

Artifact removal by template subtraction enables recordings of the frequency following response in cochlear-implant users

Scientific Reports
Electrically evoked frequency-following responses (eFFRs) provide insight in the phase-locking ability of brainstem of cochlear-implant (CI) users. eFFRs can potentially be used to gain insight in the individual differences in the biological limitation ...
Robin Gransier, Robert P. Carlyon, Matthew L. Richardson, John C. Middlebrooks, Jan Wouters   +4 more
doaj   +1 more source

Axon Initial Segment: Structure, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 4, April 2026.
The axon initial segment (AIS) is a specialized axonal domain critical for maintaining neuronal polarity, action potential initiation, and network stability. This review summarizes the necessary elements for maintaining AIS structure and plasticity, discussing crucial biological functions of AIS in neuronal signaling and the neural circuit homeostasis,
Dong‐Yan Song, Lin Yuan, Weiguo Yang, Wen Li, Jia‐Yi Li   +4 more
wiley   +1 more source

Acquisition of Subcortical Auditory Potentials With Around-the-Ear cEEGrid Technology in Normal and Hearing Impaired Listeners

Frontiers in Neuroscience, 2019
Even though the principles of recording brain electrical activity remain unchanged since their discovery, their acquisition has seen major improvements. The cEEGrid, a recently developed flex-printed multi-channel sensory array, can be placed around the ...
Markus Garrett, Markus Garrett, Stefan Debener, Stefan Debener, Sarah Verhulst   +4 more
doaj   +1 more source