Results 1 to 10 of about 32,011 (109)

Surgical and Electrical Anatomy of the Inter-Nodal and Intra-Atrial Conduction System in the Heart

Journal of Chest Surgery, 2022
An anatomical understanding of the atrial myocardium is crucial for surgeons and interventionists who treat atrial arrhythmias. We reviewed the anatomy of the inter-nodal and intra-atrial conduction systems.
Jeong-Wook Seo, Jung-Sun Kim, Myung-Jin Cha, Ja Kyoung Yoon, Min-Ju Kim, Hsuan-Ming Tsao, Chang-Ha Lee, Seil Oh   +7 more
doaj   +3 more sources

Conduction system pacing versus biventricular pacing in heart failure with reduced ejection fraction and electrical dyssynchrony

Frontiers in Cardiovascular Medicine
Biventricular pacing (BiVP) has been the cornerstone of cardiac resynchronization therapy (CRT) in the management of symptomatic heart failure patients with reduced ejection fraction (HFrEF) and electrical dyssynchrony despite guideline-directed medical ...
Ahmed Ammar, Ahmed Ammar, Ahmed Elewa, Amr Y. Emam, Mohamed Sharief, Omnia Kamel   +5 more
doaj   +2 more sources

Conduction defects and arrhythmias in mdx mice are not associated with a degeneration of the cardiac Purkinje network [PDF]

Frontiers in Physiology
Duchenne muscular dystrophy (DMD) is a severe X-chromosomal disease characterised by progressive muscle weakness and degeneration. Cardiac involvement is inevitable in DMD patients and ventricular arrhythmias are a high-risk factor for mortality in these
Juliette Vahdat, Jakob Sauer, Jessica Marksteiner, Karlheinz Hilber, Lucile Miquerol   +4 more
doaj   +2 more sources

An endogenous cholinergic system controls electrical conduction in the heart. [PDF]

Eur Heart J
Xie D, Xiong K, Dong N, Wang G, Zou Q, Shao B, Chen Z, Wang L, Kong Y, Wang X, Su X, Bai W, Yang J, Liu Y, Zhou B, Chen YH.   +15 more
europepmc   +2 more sources

Engineering a conduction-consistent cardiac patch with rGO/PLCL electrospun nanofibrous membranes and human iPSC-derived cardiomyocytes

Frontiers in Bioengineering and Biotechnology, 2023
The healthy human heart has special directional arrangement of cardiomyocytes and a unique electrical conduction system, which is critical for the maintenance of effective contractions.
Yao Tan, Ying Chen, Tingting Lu, Nevin Witman, Bingqian Yan, Yiqi Gong, Xuefeng Ai, Li Yang, Li Yang, Minglu Liu, Runjiao Luo, Huijing Wang, Stefano Ministrini, Stefano Ministrini, Wei Dong, Wei Wang, Wei Fu, Wei Fu   +17 more
doaj   +1 more source

Direct reprogramming of cardiomyocytes into cardiac Purkinje-like cells

iScience, 2022
Summary: Currently, there are no treatments that ameliorate cardiac cell death, the underlying basis of cardiovascular disease. An unexplored cell type in cardiac regeneration is cardiac Purkinje cells; specialized cells from the cardiac conduction ...
Nicole Prodan, Faheem Ershad, Arfaxad Reyes-Alcaraz, Luge Li, Brandon Mistretta, Lei Gonzalez, Zhoulyu Rao, Cunjiang Yu, Preethi H. Gunaratne, Na Li, Robert J. Schwartz, Bradley K. McConnell   +11 more
doaj   +1 more source

Regulation of Cardiac Conduction and Arrhythmias by Ankyrin/Spectrin-Based Macromolecular Complexes

Journal of Cardiovascular Development and Disease, 2021
The cardiac conduction system is an extended network of excitable tissue tasked with generation and propagation of electrical impulses to signal coordinated contraction of the heart.
Drew Nassal, Jane Yu, Dennison Min, Cemantha Lane, Rebecca Shaheen, Daniel Gratz, Thomas J. Hund   +6 more
doaj   +1 more source

Case report: Challenges and implications of conduction system pacing in pediatrics: Case series

Frontiers in Pediatrics, 2023
Cardiac electrical stimulation in children usually is needed in the setting of complete congenital atrioventricular block, atrioventricular block after heart surgery, and bradycardia associated with some specific channelopathies.
Ruy Gonzalo Ploneda Valencia, Moisés Levinstein Jacinto, Carmen A. Sánchez Contreras, Gustavo Ruiz González, Diego Neach de la Vega, Manlio F. Márquez Murillo, Santiago Nava   +6 more
doaj   +1 more source

Connexin diversity in the heart: insights from transgenic mouse models

Frontiers in Pharmacology, 2013
Cardiac conduction is mediated by gap junction channels that are formed by connexin (Cx) protein subunits. The connexin family of proteins consists of 24 members, varying in their biophysical properties and ability to combine with other connexins into ...
Sander eVerheule, Sven eKaese
doaj   +1 more source

Genetic and physiologic dissection of the vertebrate cardiac conduction system. [PDF]

PLoS Biology, 2008
Vertebrate hearts depend on highly specialized cardiomyocytes that form the cardiac conduction system (CCS) to coordinate chamber contraction and drive blood efficiently and unidirectionally throughout the organism.
Neil C Chi, Robin M Shaw, Benno Jungblut, Jan Huisken, Tania Ferrer, Rima Arnaout, Ian Scott, Dimitris Beis, Tong Xiao, Herwig Baier, Lily Y Jan, Martin Tristani-Firouzi, Didier Y R Stainier   +12 more
doaj   +1 more source