Results 21 to 30 of about 35,322 (230)

Feasibility of selective cardiac ventricular electroporation.

PLoS ONE, 2020
IntroductionThe application of brief high voltage electrical pulses to tissue can lead to an irreversible or reversible electroporation effect in a cell-specific manner. In the management of ventricular arrhythmias, the ability to target different tissue
Alan Sugrue, Vaibhav R Vaidya, Christopher Livia, Deepak Padmanabhan, Anas Abudan, Ameesh Isath, Tyra Witt, Christopher V DeSimone, Paul Stalboerger, Suraj Kapa, Samuel J Asirvatham, Christopher J McLeod   +11 more
doaj   +1 more source

Segregation of Central Ventricular Conduction System Lineages in Early SMA+ Cardiomyocytes Occurs Prior to Heart Tube Formation

Journal of Cardiovascular Development and Disease, 2016
The cardiac conduction system (CCS) transmits electrical activity from the atria to the ventricles to coordinate heartbeats. Atrioventricular conduction diseases are often associated with defects in the central ventricular conduction system comprising ...
Caroline Choquet, Laetitia Marcadet, Sabrina Beyer, Robert G. Kelly, Lucile Miquerol   +4 more
doaj   +1 more source

Renal denervation reverses ventricular structural and functional remodeling in failing rabbit hearts

Scientific Reports, 2023
Renal denervation (RDN) suppresses the activity of the renin–angiotensin–aldosterone system and inflammatory cytokines, leading to the prevention of cardiac remodeling.
Ting-Chun Huang, Li-Wei Lo, Yu-Hui Chou, Wei-Lun Lin, Shih-Lin Chang, Yenn-Jiang Lin, Shin-Huei Liu, Wen-Han Cheng, Ping-Yen Liu, Shih-Ann Chen   +9 more
doaj   +1 more source

An endogenous cholinergic system controls electrical conduction in the heart

European Heart Journal
Abstract Background and Aims The cholinergic system is distributed in the nervous system, mediating electrical conduction through acetylcholine (ACh). This study aims to identify whether the heart possesses an intact endogenous cholinergic system and to explore its electrophysiological functions and ...
Duanyang Xie, Ke Xiong, Nianguo Dong, Guanghua Wang, Qicheng Zou, Beihua Shao, Zhiwen Chen, Luxin Wang, Yu Kong, Xu Wang, Xuling Su, Wenli Bai, Jian Yang, Yi Liu, Bin Zhou, Yi-Han Chen   +15 more
openaire   +2 more sources

PHYSIOLOGICAL STIMULATION OF THE HEART – HISTORY AND THE PRESENT

Праці Наукового товариства імені Шевченка. Медичні науки
The possibility of electrical stimulation of the heart has fascinated researchers and doctors since the Age of Enlightenment until the 21st century.
Оleksiy Myshakivskyy, Marta Voytsekhivska, Volodymyr Pavliuk   +2 more
doaj   +1 more source

Conduction System Pacing for Cardiac Resynchronization Therapy

Journal of Cardiovascular Development and Disease, 2023
Cardiac resynchronization therapy (CRT) via biventricular pacing (BiVP-CRT) is considered a mainstay treatment for symptomatic heart failure patients with reduced ejection fraction and wide QRS. However, up to one-third of patients receiving BiVP-CRT are
Óscar Cano, Javier Navarrete-Navarro, Pablo Jover, Joaquín Osca, Maite Izquierdo, Josep Navarro, Hebert D. Ayala, Luis Martínez-Dolz   +7 more
doaj   +1 more source

Phenotypically silent Cre recombination within the postnatal ventricular conduction system. [PDF]

PLoS ONE, 2017
The cardiac conduction system (CCS) is composed of specialized cardiomyocytes that initiate and maintain cardiac rhythm. Any perturbation to the normal sequence of electrical events within the heart can result in cardiac arrhythmias.
Samadrita Bhattacharyya, Minoti Bhakta, Nikhil Vilas Munshi   +2 more
doaj   +1 more source

Conduction defects and arrhythmias in mdx mice are not associated with a degeneration of the cardiac Purkinje network

Frontiers in Physiology
Duchenne muscular dystrophy (DMD) is a severe X-chromosomal disease characterised by progressive muscle weakness and degeneration. Cardiac involvement is inevitable in DMD patients and ventricular arrhythmias are a high-risk factor for mortality in these
Juliette Vahdat, Jakob Sauer, Jessica Marksteiner, Karlheinz Hilber, Lucile Miquerol   +4 more
doaj   +1 more source

Identification and functional characterization of cardiac pacemaker cells in zebrafish.

PLoS ONE, 2012
In the mammalian heart a conduction system of nodes and conducting cells generates and transduces the electrical signals evoking myocardial contractions. Specialized pacemaker cells initiating and controlling cardiac contraction rhythmicity are localized
Federico Tessadori, Jan Hendrik van Weerd, Silja B Burkhard, Arie O Verkerk, Emma de Pater, Bastiaan J Boukens, Aryan Vink, Vincent M Christoffels, Jeroen Bakkers   +8 more
doaj   +1 more source

Aspects of myocardial heterogeneity in assessment its remodeling

RUDN Journal of Medicine, 2022
The influence of sports activity on the cardiovascular system is accompanied by physiological adaptation of the organism. Intense physical activity, far exceeding the body’s capabilities, can lead to structural changes or remodeling of the athlete’s ...
Elena N. Minina, Evgeny E. Stepura
doaj   +1 more source