Results 11 to 20 of about 32,011 (109)

Advances and Prospects in Understanding Vertebrate Cardiac Conduction System, Pacemaker Cell, and Cardiac Muscle Development: Toward Novel Biological Therapies

Muscles, 2023
The heart is composed of muscle cells called cardiomyocytes, including a specialized population named pacemaker cells that form the cardiac conduction system (CCS), which is responsible for generating the action potential dictating heart contractions ...
Ridwan Opeyemi Bello, Shannon Frew, Yusra Siddiqui, Rashid Minhas   +3 more
doaj   +1 more source

Emerging from the Darkness. Sudden Cardiac Death in Cardiac Amyloidosis

Reviews in Cardiovascular Medicine, 2022
Cardiac amyloidosis (CA) manifests as infiltrative cardiomyopathy with a hypertrophic pattern, usually presenting with heart failure with a preserved ejection fraction. In addition, degenerative valvular heart disease, particularly severe aortic stenosis,
Valeria Cammalleri, Valeria Maria De Luca, Giorgio Antonelli, Ombretta Annibali, Annunziata Nusca, Simona Mega, Myriam Carpenito, Danilo Ricciardi, Fiorella Gurrieri, Giuseppe Avvisati, Gian Paolo Ussia, Francesco Grigioni   +11 more
doaj   +1 more source

Restoring heart function and electrical integrity: closing the circuit

npj Regenerative Medicine, 2017
Cardiovascular diseases are the main cause of death in the world and are often associated with the occurrence of arrhythmias due to disruption of myocardial electrical integrity.
Luís Miguel Monteiro, Francisco Vasques-Nóvoa, Lino Ferreira, Perpétua Pinto-do-Ó, Diana Santos Nascimento   +4 more
doaj   +1 more source

Erbb2 is required for cardiac atrial electrical activity during development.

PLoS ONE, 2014
The heart is the first organ required to function during embryonic development and is absolutely necessary for embryo survival. Cardiac activity is dependent on both the sinoatrial node (SAN), which is the pacemaker of heart's electrical activity, and ...
Gennadiy Tenin, Christopher Clowes, Kathryn Wolton, Eliska Krejci, Jayne A Wright, Simon C Lovell, David Sedmera, Kathryn E Hentges   +7 more
doaj   +1 more source

Syncytium calcium signaling and macrophage function in the heart

Cell & Bioscience, 2018
Macrophages are traditionally viewed as a key component of the immunity defense system. Recent studies have identified resident macrophages in multiple organs including the heart, in which the cells perform their crucial role on tissue repair after ...
Xin Zhou, Zhongguang Li, Zefan Wang, Eda Chen, Juan Wang, Frederic Chen, Odell Jones, Tao Tan, Shawn Chen, Hiroshi Takeshima, Joseph Bryant, Jianjie Ma, Xuehong Xu   +12 more
doaj   +1 more source

Identifying the evolutionary building blocks of the cardiac conduction system.

PLoS ONE, 2012
The endothermic state of mammals and birds requires high heart rates to accommodate the high rates of oxygen consumption. These high heart rates are driven by very similar conduction systems consisting of an atrioventricular node that slows the ...
Bjarke Jensen, Bastiaan J D Boukens, Alex V Postma, Quinn D Gunst, Maurice J B van den Hoff, Antoon F M Moorman, Tobias Wang, Vincent M Christoffels   +7 more
doaj   +1 more source

Early experience with permanent pacemaker implantation at a tertiary hospital in Nigeria

The Pan African Medical Journal, 2020
INTRODUCTION: Artificial pacemakers generate electrical impulses and regulate the heart´s conduction system. They are often used to treat individuals with bradycardia. Permanent pacemaker implantation is a lifesaving procedure especially in patients with
Uvie Ufuoma Onakpoya, Olugbenga Olalekan Ojo, Oghenevware Joel Eyekpegha, Abayomi Emmanuel Oguns, Anthony Olubunmi Akintomide   +4 more
doaj   +1 more source

Predictive factors of atrioventricular conduction disorders [PDF]

Romanian Medical Journal
Atrioventricular conduction disorders represent an alteration in the normal function of the heart’s electrical conduction system, a system that connects the atria and ventricles through the atrio-ventricular node and the His-Purkinje system. Consequently,
Carmen Marina Deutsch, Elisabeta Badila, Adriana Iliesiu   +2 more
doaj   +1 more source

Current views on heart rhythm disturbance in patients with type 2 diabetes mellitus who underwent implantation of a permanent pacemaker (a literature review)

Zaporožskij Medicinskij Žurnal, 2020
Aim – to analyse specialized literature and study the effect of type 2 diabetes mellitus on the cardiac conduction system in patients with a permanent pacemaker. Conclusions.
M. S. Brynza , O. S. Voronenko
doaj   +1 more source

Recovery of complete left bundle branch block in dilated cardiomyopathy after optimal heart failure treatment: a case report [PDF]

Journal of Medicine and Life Science
Complete left bundle branch block (CLBBB) is a significant cardiac conduction abnormality often associated with dilated cardiomyopathy (DCM). This case report highlights the improvement in CLBBB and symptom relief through reverse cardiac remodeling in a ...
Geum Ko, Jae-Geun Lee
doaj   +1 more source