High resolution 3-Dimensional imaging of the human cardiac conduction system from microanatomy to mathematical modeling [PDF]
Scientific Reports, 2017 Cardiac arrhythmias and conduction disturbances are accompanied by structural remodelling of the specialised cardiomyocytes known collectively as the cardiac conduction system.
Robert S. Stephenson +11 more
doaj +2 more sources
Regulation of Cardiac Conduction and Arrhythmias by Ankyrin/Spectrin-Based Macromolecular Complexes
Journal of Cardiovascular Development and Disease, 2021 The cardiac conduction system is an extended network of excitable tissue tasked with generation and propagation of electrical impulses to signal coordinated contraction of the heart.
Drew Nassal +6 more
doaj +1 more source
Case report: Challenges and implications of conduction system pacing in pediatrics: Case series
Frontiers in Pediatrics, 2023 Cardiac electrical stimulation in children usually is needed in the setting of complete congenital atrioventricular block, atrioventricular block after heart surgery, and bradycardia associated with some specific channelopathies.
Ruy Gonzalo Ploneda Valencia +6 more
doaj +1 more source
Real-time optical manipulation of cardiac conduction in intact hearts [PDF]
, 2018 Optogenetics has provided new insights in cardiovascular research, leading to new methods for cardiac pacing, resynchronization therapy and cardioversion.
Bocchi, L. +16 more
core +2 more sources
Connexin diversity in the heart: insights from transgenic mouse models
Frontiers in Pharmacology, 2013 Cardiac conduction is mediated by gap junction channels that are formed by connexin (Cx) protein subunits. The connexin family of proteins consists of 24 members, varying in their biophysical properties and ability to combine with other connexins into ...
Sander eVerheule, Sven eKaese
doaj +1 more source
Muscles, 2023 The heart is composed of muscle cells called cardiomyocytes, including a specialized population named pacemaker cells that form the cardiac conduction system (CCS), which is responsible for generating the action potential dictating heart contractions ...
Ridwan Opeyemi Bello +3 more
doaj +1 more source
Electrical activation of the ventricular myocardium of the crocodile Crocodylus johnstoni: A combined microscopic and electrophysiological study [PDF]
, 1999 We mapped the sequence of ventricular depolarization in the crocodile Crocodylus johnstoni. We also attempted to find specialized conduction tissue within the ventricular myocardium.
Burggren +18 more
core +2 more sources
Genetic and physiologic dissection of the vertebrate cardiac conduction system. [PDF]
PLoS Biology, 2008 Vertebrate hearts depend on highly specialized cardiomyocytes that form the cardiac conduction system (CCS) to coordinate chamber contraction and drive blood efficiently and unidirectionally throughout the organism.
Neil C Chi +12 more
doaj +1 more source
Emerging from the Darkness. Sudden Cardiac Death in Cardiac Amyloidosis
Reviews in Cardiovascular Medicine, 2022 Cardiac amyloidosis (CA) manifests as infiltrative cardiomyopathy with a hypertrophic pattern, usually presenting with heart failure with a preserved ejection fraction. In addition, degenerative valvular heart disease, particularly severe aortic stenosis,
Valeria Cammalleri +11 more
doaj +1 more source
Two dimensional electrophysiological characterization of human pluripotent stem cell-derived cardiomyocyte system. [PDF]
, 2017 Stem cell-derived cardiomyocytes provide a promising tool for human developmental biology, regenerative therapies, disease modeling, and drug discovery.
Gimzewski, James K +7 more
core +2 more sources