PKB-Mediated Thr649 Phosphorylation of AS160/TBC1D4 Regulates the R-Wave Amplitude in the Heart. [PDF]
PLoS ONE, 2015 The Rab GTPase activating protein (RabGAP), AS160/TBC1D4, is an important substrate of protein kinase B (PKB), and regulates insulin-stimulated trafficking of glucose transporter 4.
Chao Quan +3 more
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Surgical Outcomes of Congenital Heart Disease in Down Syndrome: Tertiary Centre Experience – Focus on the Electrical Conduction System [PDF]
, 2022 Mohammad A. Ebrahim +7 more
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Acute Isolation of Cells from Murine Sino-atrial Node
Bio-Protocol, 2020 The cardiac conduction system allows the synchronized propagation of electrical activity through heart muscle. This is initiated by the spontaneous activity of the specialized pacemaker cells of the sino-atrial node (SAN).
Qadeer Aziz +2 more
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Simplified 2D Bidomain Model of Whole Heart Electrical Activity and ECG Generation
Measurement Science Review, 2014 The aim of this study was the development of a geometrically simple and highly computationally-efficient two dimensional (2D) biophysical model of whole heart electrical activity, incorporating spontaneous activation of the sinoatrial node (SAN), the ...
Sovilj Siniša +4 more
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Forward Electrocardiogram Modeling by Small Dipoles Based on Whole-Body Electric Field Analysis
IEEE Access, 2019 Mathematical modeling of detailed cardiac function has become possible in recent years. Computer simulations have been conducted to reproduce electrical phenomena of the heart.
Tatsuhito Nakane +4 more
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Simulation of cardiac arrhythmias using a 2D heterogeneous whole heart model
Frontiers in Physiology, 2015 Simulation studies of cardiac arrhythmias at the whole heart level with electrocardiogram (ECG) gives an understanding of how the underlying cell and tissue level changes manifest as rhythm disturbances in the ECG.
Minimol eBalakrishnan +2 more
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Electrode Model and Simulation of His- Bundle Pacing for Cardiac Resynchronization Therapy
Current Directions in Biomedical Engineering, 2020 A disturbed synchronization of the ventricular contraction can cause a highly developed systolic heart failure in affected patients with reduction of the left ventricular ejection fraction, which can often be explained by a diseased left bundle branch ...
Pascual Domenic +3 more
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Clinical Medicine Insights: CardiologyA 50-year-old male had intermittent episodes of dyspnea for 7 days with persistent atrial fibrillation (AF) for 2 years. New York Heart Association (NYHA) functional class is IV status.
Bingchen Guo +8 more
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Molecular Mechanisms of Cardiac Adaptation After Device Deployment
Journal of Cardiovascular Development and DiseaseCardiac devices have transformed the management of heart failure, ventricular arrhythmias, ischemic cardiomyopathy, and valvular heart disease. Technologies such as cardiac resynchronization therapy (CRT), conduction system pacing, left ventricular ...
Letizia Rosa Romano +7 more
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Electrical Conduction System Remodeling in Streptozotocin-Induced Diabetes Mellitus Rat Heart [PDF]
, 2019 Yu Zhang +10 more
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