Results 41 to 50 of about 11,280,876 (284)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Epoxy-Based Composite Adhesive Containing Silver Coated Copper Powder: Preparation and Evaluation of Its Electrical Properties [PDF]

علوم و تکنولوژی پلیمر, 2017
The progress in scientific and technical products and increasing needs for advanced electrical and electronic devices have motivated researchers to investigate new ideas in this field.
Hamed Rikhtegar, Seyed Jamaleddin Peighambardoust, Abdolreza Mirmohseni   +2 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Structure and electrical properties of silica-based polyethylene nanocomposites

, 2013
The topic of polymer nanocomposites remains an active area of research in the dielectrics community, due to the unique electrical properties that these materials could exhibit. To explain the behaviour of these materials, the importance of clarifying the
Lau, K.Y.
core   +1 more source

The effect of Cu concentration on some of the electrical properties of CdSe films

Iraqi Journal of Physics, 2008
The CdSe pure films and doping with Cu (0.5, 1.5, 2.5, 4.0wt%) of thickness 0.9μm have been prepared by thermal evaporation technique on glass substrate. Annealing for all the prepared films have been achieved at 523K in vacuum to get good properties of
E. M. Al-Fwadi
doaj  

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Electrical and Mechanical Properties of new Recyclable Power Cable Insulation Materials based upon Polyethylene Blends

, 2011
Chemically crosslinked polyethylene (XLPE) has been used as electrical insulation for power cables since the 1970s due to its favourable combination of electrical and mechanical properties.
Green, C.D., Fairhurst, M.J., Sutton, S.J., Geussens, T., Stevens, G.C., Vaughan, A.S.   +5 more
core   +1 more source

Studies of electrical conductivity and magnetic properties of Bi1-xGdxFeO3 multiferroics [PDF]

Journal of Advanced Dielectrics, 2014
The polycrystalline samples of Bi1-xGdxFeO3 (x = 0, 0.1, and 0.2) multiferroic oxides have been synthesized by a solid-state reaction/mixed oxide technique.
Samita Pattanayak, R. N. P. Choudhary, Piyush R. Das   +2 more
doaj   +1 more source

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias, Federica Avantaggiato, Gianni Pezzoli, Andrea Canessa   +3 more
wiley   +1 more source