Do's and Don'ts When Visiting Circularly Polarized Luminescence
This perspective presents our insights into the principles, challenges, and opportunities of circularly polarized luminescence (CPL). Highlighting key concepts such as the dissymmetry factor (glum) and molecular design strategies, we discuss advances in CPL efficiency, emerging NIR emitters, solid‐state applications, and the growing role of theory and ...
Rafael G. Uceda +9 more
wiley +1 more source
Organic and Metallacages for Chemical Sensing: Progress in Water‐Compatible Systems
Supramolecular cages function as three‐dimensional receptors for selective molecular recognition and sensing, and this review outlines design principles for water‐stable architectures, key analyte‐ and medium‐dependent challenges, recent water‐compatible examples (including polymer‐integrated systems), and future opportunities for cage‐based ...
Rabia Zahid +4 more
wiley +1 more source
Nuclear Factor I‐B Delays Liver Fibrosis by Inhibiting Chemokine Ligand 5 Transcription
This study identifies the transcription factor Nuclear Factor I‐B (NFIB) as a key suppressor of liver fibrosis. NFIB expression declines during hepatic stellate cell activation, and its overexpression reduces fibrosis in mice models. The mechanism involves NFIB directly repressing chemokine C─C motif ligand 5 (CCL5), thereby alleviating oxidative ...
Qianqian Chen +14 more
wiley +1 more source
Biomimetic membrane interface engineering constructs functionalized detection platforms by integrating natural cell membranes, synthetic lipids, or hybrid membranes. This strategy effectively reduces background interference and enables efficient target capture and analysis, showing broad applications in circulating tumor cell separation, extracellular ...
Duo Liu +8 more
wiley +1 more source
Multidisciplinary cutting-edge technologies accelerating target-based drug discovery. [PDF]
Li Y, Moaddel R, Jiang Z, Chen X.
europepmc +1 more source
Dual‐Mediated Aggregate Electrochemiluminescence of Rubrene
Tripropylamine meets triarylamine: The electrochemiluminescence (ECL) behaviors of rubrene (RUB) in aqueous conditions were revolutionized by the inclusion of a triarylamine molecule (TPD) as both redox and supramolecular mediators. ABSTRACT Electrochemiluminescence (ECL) populates the luminescent excited states through electrochemical reactions. It is
Li Dai +9 more
wiley +1 more source
Highly Sensitive Electrochemiluminescence Analysis of miRNA-107 Using AIE-Active Polymer Dots as Emitters. [PDF]
Xu ZH +7 more
europepmc +1 more source
Aerogel Scaffolds: Breathing Life Into Tissue Repair and Companion Diagnostics
Aerogel scaffolds are emerging as multifunctional biomedical platforms that bridge regenerative engineering and molecular diagnostics. By integrating hierarchical porosity, tunable mechanics, and programmable surface chemistry, aerogels can simultaneously support tissue reconstruction and enable localized biomarker sampling and signal transduction ...
Hanlin Zhang +5 more
wiley +1 more source
Suspected Central Adrenal Insufficiency in a Patient with Phosphomannomutase 2-Congenital Disorder of Glycosylation. [PDF]
Ødum SF +3 more
europepmc +1 more source
Tracking early cognitive decline in preclinical AD with brain MRI similarity
Abstract INTRODUCTION Early detection of neuroanatomical changes in preclinical Alzheimer's disease (AD) is critical for timely intervention. However, conventional magnetic resonance imaging (MRI) and fluid biomarkers often lack sensitivity to subtle structural alterations in early disease stages. METHODS To identify early brain alterations, we applied
Jiawei Sun +6 more
wiley +1 more source

