Results 71 to 80 of about 48,773 (265)

Photoinduced Electrochemiluminescence Immunoassays

Analytical Chemistry
Optimization of electrochemiluminescence (ECL) immunoassays is highly beneficial for enhancing clinical diagnostics. A major challenge is the improvement of the operation conditions required for the bead-based immunoassays using the typical [Ru(bpy)3]2+/tri-n-propylamine (TPrA) system.
Dongni Han, Jasmina Vidic, Dechen Jiang, Gabriel Loget, Neso Sojic   +4 more
openaire   +4 more sources

An Insulin‐Exosome‐TNFAIP8 Axis Drives Stromal Fibrosis and Therapeutic Resistance in Pancreatic Cancer

Advanced Science, EarlyView.
In pancreatic ductal adenocarcinoma (PDAC), insulin is associated with activation of PI3K/AKT–RAB3A signaling and enhanced secretion of TNFAIP8‐enriched exosomes from tumor cells. Uptake of these exosomes by fibroblasts is linked to TRIM21‐dependent STAT1 degradation and the emergence of myofibroblastic CAF–associated features, accompanied by increased
Zhenyu Li, Li Chen, Tao Wang, Haiyang Jiang, Huijuan Wang, Mengyu Li, Guanpeng Xie, Chunhua Xi, Han Yan, Chunhui Lu, Chenchen Li, Hanyu Zhu, Feihu Sun, Lingdi Yin, Jun Yu, Yi Miao   +15 more
wiley   +1 more source

Proline‐Selective Electrochemiluminescence Detecting a Single Amino Acid Variation Between A1 and A2 β‐Casein Containing Milks

Advanced Science
The proline amino acid and prolyl residues of peptides/proteins confer unique biological and biochemical properties that motivates the development of proline‐selective analysis.
Eunkyoung Kim, Chen‐Yu Chen, Monica J. Chu, Mya F. Hamstra, William E. Bentley, Gregory F. Payne   +5 more
doaj   +1 more source

Carbon Dots: An Emerging Smart Material for Analytical Applications

Micromachines, 2021
Carbon dots (CDs) are optically active carbon-based nanomaterials. These nanomaterials can change their light emission properties in response to various external stimuli such as pH, temperature, pressure, and light. The CD’s remarkable stimuli-responsive
Smita Das, Lightson Ngashangva, Pranab Goswami   +2 more
doaj   +1 more source

Aggregation‐Induced Resonance Energy Transfer in Polymer Dots to Boost Electrochemiluminescence Performance for Bioimaging of Glycan on Cells

Advanced Science, EarlyView.
This study pioneers an aggregation‐induced resonance energy transfer mechanism by synergistically integrating aggregation‐induced emission (AIE), resonance energy transfer (RET), and thermally activated delayed fluorescence (TADF) within co‐reactant conjugated polymers to develop self‐enhanced ECL emitters, which achieves an ECL efficiency up to 92.6 ...
Chao Wang, Mengjiao Li, Yiran Li, Xiangfu Hu, Chunlan Li, Ningning Wang, Huangxian Ju   +6 more
wiley   +1 more source

Electrochemiluminescence Aptasensor Based on Gd(OH)₃ Nanocrystalline for Ochratoxin A Detection in Food Samples

Biosensors, 2022
In the present study, the electrochemiluminescence (ECL) properties of Gd(OH)3 nanocrystals with K2S2O8 as the cathode coreactant were studied for the first time.
Chunyuan Tian, Minggang Wei, Xiaobin Wang, Qing Hua, Feiyan Tang, Lijun Zhao, Xuming Zhuang, Feng Luan   +7 more
doaj   +1 more source

The effect of three years of TNF alpha blocking therapy on markers of bone turnover and their predictive value for treatment discontinuation in patients with ankylosing spondylitis: a prospective longitudinal observational cohort study [PDF]

, 2012
INTRODUCTION: The aim of this study was to investigate the effect of three years of tumor necrosis factor-alpha (TNF-alpha) blocking therapy on bone turnover as well as to analyze the predictive value of early changes in bone turnover markers (BTM) for ...
Arends, S., Bos, R., Brouwer, E., Groen, H., Houtman, P.M., Kallenberg, C.G., Leijsma, M.K., Spoorenberg, A., van der Veer, E.   +8 more
core   +4 more sources

Robotic Arm‐Assisted Conformal 3D Printing of Displays for Structural Electronics

Advanced Intelligent Systems, EarlyView.
This study presents a robotics‐enabled platform combining 3D scanning and a 6‐DOF robotic arm for conformal printing on complex non‐planar structures. By maintaining nozzle perpendicularity, the system enables high‐fidelity direct ink writing on steep sidewalls, spherical surfaces, successfully demonstrating a fully printed 7‐segment dynamic display ...
Chanbin Yoo, Jongcheon Bae, Seonghyeon Kim, Jun Chang Yang, Seung Kwon Seol, Jaeyeon Pyo   +5 more
wiley   +1 more source

Oocyte maturation in the toad Rhinella arenarum (Amphibia, Anura): Evidence of cAMP involvement in steroid production and action [PDF]

, 2018
In this work, we describe the participation of the adenylate cyclase/3′-5′-cyclic adenonsine monophosphate (cAMP) pathway in the seasonal follicular secretion of progesterone (P 4 ) and testosterone (T), and its relationship with the maturation of ...
Arias Torres, Arias Torres, Canosa, Cerdá, Das, Deng, Eyers, Ferrell, Fortune, Gohin, Gohin, Hammes, Higashijima, Jalabert, Kamangar, Khan, Kwon, Kwon, Levin, Lin, Lin, Lubzens, Marteil, Medina, Miedlich, Nader, Nagahama, Norris, O'Brien, Pang, Pickford, Rasar, Romo, Sadler, Schuetz, Sen, Sen, Smith, Sánchez Toranzo, Sánchez Toranzo, Thomas, Voronina, Vu, White, Yamamoto, Yang, Zelarayán, Zelarayán, Zelarayán   +48 more
core   +1 more source

Novel Monoclonal Antibody Detects Small Aβ Oligomers More Sensitively Than Lecanemab in Alzheimer's Disease CSF, Serum and Culture Media

Annals of Neurology, EarlyView.
Objective Aqueously diffusible oligomers of the amyloid β‐protein (oAβ) are neurotoxic and play a role in neuronal dysfunction in Alzheimer's disease (AD). Accurate quantification of oAβ in brains and biofluids could be valuable for understanding and monitoring AD.
Yi Ran Xu, Youqi Tao, Alexandra M. Lish, Shaomin Li, Beth L. Ostaszewski, Amirah K. Anderson, Tracy Young‐Pearse, Trebor L. Lawton, Hyun‐Sik Yang, Dominic M. Walsh, Ting Yang, Dennis J. Selkoe   +11 more
wiley   +1 more source