Results 71 to 80 of about 2,094,383 (285)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Electron Heating in Magnetosheath Turbulence: Dominant Role of the Parallel Electric Field Within Coherent Structures

Geophysical Research Letters, 2023
How particles are being energized by turbulent electromagnetic fields is an outstanding question in plasma physics and astrophysics. This paper investigates the electron acceleration mechanism in strong turbulence (δB/B0 ∼ 1) in the Earth's magnetosheath
Qianyun Xu, Meng Zhou, Wenqing Ma, Jiansen He, Shiyong Huang, Zhihong Zhong, Ye Pang, Xiaohua Deng   +7 more
doaj   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Radiation damage to undulator electronics at an electron accelerator

Journal of Physics: Conference Series, 2019
Abstract Experience gained from commissioning and operation of three elliptical polarization undulators (EPU) at the TPS taught us that undulator driving systems can behave erratically following a beam dump or loss. In this work, we discuss possible harmful radiation sources in a storage ring and analyse the effect of lack of electronic ...
Chung, Ting-Yi, Chang, Cheng-Hsiang, Chen, Ang-Yu, Chen, Yi-Wei, Huang, Jui-Che, Jan, Jyh-Chyuan   +5 more
openaire   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Electron acceleration sites in a large-scale coronal structure [PDF]

, 1997
Radio observations and interplanetary particle measurements have shown that even in the absence of conspicuous violent processes in the low atmosphere (such as Hα flares) electrons are accelerated in the corona, most likely at higher altitudes than ...
Soru-Escaut, I., Klein, K.-L., Aurass, H., Kálmán, Béla   +3 more
core   +1 more source

Ultra-high charge electron acceleration for nuclear applications

Fundamental Plasma Physics
Ultra-intense laser-plasma wakefield accelerator possess several superior properties compared with the traditional radio-frequency accelerators. These characteristics include femtosecond duration, micro-source size, and ultra-dense beam density, result ...
Liming Chen, Jie Feng, Wenchao Yan, Hao Xu, Yaojun Li, Wenzhao Wang, Xulei Ge, Xiaojun Huang, Jie Zhang   +8 more
doaj   +1 more source

Global optimization of the electron acceleration by a Gaussian beam

Results in Physics, 2017
For vacuum electron acceleration by a Gaussian beam, the energy gain of the electron is sensitively influenced by the initial parameters of the electron and the laser beam.
Jian Xu, Zhen-Jun Yang, Jian-Xing Li, Wei-Ping Zang   +3 more
doaj   +1 more source

A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions

Advanced Engineering Materials, EarlyView.
This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice, Krzysztof S. Stopka, Michael D. Sangid   +2 more
wiley   +1 more source