Results 81 to 90 of about 4,690,653 (292)

Comparison of bulk electron density and voxel‐based electron density treatment planning [PDF]

Journal of Applied Clinical Medical Physics, 2011
The use of magnetic resonance imaging (MRI) alone for radiation planning is limited by the lack of electron density for dose calculations. The purpose of this work is to evaluate the dosimetric accuracy of using bulk electron density as a substitute for computed tomography (CT)‐derived electron density in intensity‐modulated radiation therapy (IMRT ...
Karotki, Aliaksandr, Mah, Katherine, Meijer, Gert, Meltsner, Michael   +3 more
openaire   +2 more sources

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Collimated fast electron beam generation in critical density plasma [PDF]

, 2014
Significantly collimated fast electron beam with a divergence angle 10° (FWHM) is observed when an ultra-intense laser pulse (I = 1014 W/cm2, 300 fs) irradiates a uniform critical density plasma. The uniform plasma is created through the ionization of an
Nakatsutsumi, M., J. Fuchs, Morita, K., C. Rousseaux, W. Nazarov, M. Nakatsutsumi, Baton, S., Habara, H., Tanaka, K.A., F. Filippi, H. Habara, K. Morita, S. Baton, T. Iwawaki, FILIPPI, FRANCESCO, Iwawaki, T., Chen, S., Filippi, F., S. Chen, Tanaka, K. A., Iwawaki, T, K. A. Tanaka, Fuchs, J., Nazarov, W., Rousseaux, C.   +24 more
core   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

On the Sign of Local Temperature in Molecules

Entropy, 1999
: Lin proposed earlier based on qualitative considerations that electronic motion was associated with negative absolute temperature. Here, a local temperature formula is proposed for electronic motion in atoms and molecules, which allows the existence of
István Kolossváry
doaj   +1 more source

Ionosphere over Ukrainian Antarctic Akademik Vernadsky station under minima of solar and magnetic activities, and daily insolation: case study for June 2019

Український антарктичний журнал, 2020
We present ionospheric observational results obtained over Ukrainian Antarctic Akademik Vernadsky station. Ionospheric parameters (peak electron density and height, electron density and electron and ion temperatures in the topside) during the period near
O. V. Bogomaz, M. O. Shulha, D. V. Kotov, T. G. Zhivolup, A. V. Koloskov, A. V. Zalizovski, S. B. Kashcheyev, A. I. Reznychenko, M. R. Hairston, V. Truhlik   +9 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Topside Ionosphere During the Mother's Day Superstorm as Observed by Multiple LEO Spacecraft, Including SNIPE

Space Weather
We analyze the topside electron density and temperature during the superstorm in May 2024 (Mother's Day storm or Gannon storm), using multiple Low‐Earth Orbit (LEO) spacecraft operating at different altitudes, such as Swarm, International Space Station ...
Hosub Song, Jaeheung Park, Jaejin Lee, Tae‐Yong Yang, Jongdae Sohn, Young‐Sil Kwak, Yukinaga Miyashita, Youngbum Song, Ki‐Hwan Keum, Chae‐Ryeong Kim, Yu Yi, Magnus Ivarsen, L. B. N. Clausen, Hae‐Dong Kim, Wonsub Choi, Dong‐Hyun Cho, Min‐Ki Kim, Jin‐Hyung Kim, Ji‐Seok Kim, Kiduck Kim, Seongmin Lim   +20 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source