Results 71 to 80 of about 6,081,547 (327)

Fluorescence-Based Detection of Membrane Fusion State on a Cryo-EM Grid using Correlated Cryo-Fluorescence and Cryo-Electron Microscopy

Microscopy and Microanalysis, 2019
Correlated light and electron microscopy (CLEM) has become a popular technique for combining the protein-specific labeling of fluorescence with electron microscopy, both at room and cryogenic temperatures.
L. Metskas, John A. G. Briggs
semanticscholar   +1 more source

Topological Homogeneity for Electron Microscopy Images [PDF]

, 2019
In this paper, the concept of homogeneity is defined, from a topological perspective, in order to analyze how uniform is the material composition in 2D electron microscopy images. Topological multiresolution parameters are taken into account to obtain
A Gonzalo, A Pikazi, AM Yaglom, B Materm, B Ripley, DF Reyes, GB Stringfellow, H Cramer, H Mantz, IH Ho, LJ Wu, M Barros Neiva, N Ahsan, RL Miller, S Sonali Dash, SB Zhang, V Braza, WK Cheah, ZH Wu   +18 more
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Probing electronic structure in berkelium and californium via an electron microscopy nanosampling approach

Nature Communications, 2021
The obtention and study of actinide elements is challenging due to various factors including their radioactivity and scarcity. Herein, the authors characterize the atomic and electronic structure of Am, Cm, Bk, and Cf compounds using a transmission ...
Alexander Müller, Gauthier J.-P. Deblonde, Peter Ercius, Steven E. Zeltmann, Rebecca J. Abergel, Andrew M. Minor   +5 more
doaj   +1 more source

Postsynaptic protein organization revealed by electron microscopy. [PDF]

, 2019
Neuronal synapses are key devices for transmitting and processing information in the nervous system. Synaptic plasticity, generally regarded as the cellular basis of learning and memory, involves changes of subcellular structures that take place at the ...
Bi, Guo-Qiang, Lau, Pak-Ming, Liu, Yun-Tao, Tao, Chang-Lu, Zhou, Z Hong   +4 more
core  

Single-crystal silver nanowires: Preparation and Surface-enhanced Raman Scattering (SERS) property

, 2011
Ordered Ag nanowire arrays with high aspect ratio and high density self-supporting Ag nanowire patterns were successfully prepared using potentiostatic electrodeposition within the confined nanochannels of a commercial porous anodic aluminium oxide (AAO)
alizadeh, Baoliang Sun, Chaney, Cheng, Drachev, Hu, Kim, Kong, Mardilovich, Moskovits, Mulvaney, Nikoobakht, Pan, Riveros, Shuxi Dai, Tian, Xiaohong Jiang, Yang, Yao, Zuliang Du   +19 more
core   +1 more source

Synthesis and characterization of spherical amorphous alumo-silicate nanoparticles using RF thermal plasma method [PDF]

, 2013
The RF thermal plasma synthesis route was used for the preparation of alumo-silicate spherical particles. Homogeneous solid mixtures of raw materials (Al2O3, SiO2 and KOH) were used as precursors.
Jankeviciutea, Audrone, Kareivaa, Aivaras, Károly, Zoltán, Szépvölgyi, János, Tarakinac, Nadezda V.   +4 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Segmentation of Sedimentary Grain in Electron Microscopy Image [PDF]

, 2013
This paper describes a novel method developed for the segmentation of sedimentary grains in electron microscopy images. The algorithm utilizes the approach of region splitting and merging.
Krizova, L., Krupka, A., Riha, K.
core   +1 more source