Results 41 to 50 of about 4,191,344 (254)

Electron-Transfer-Driven Trans-Ligand Labilization:  A Novel Activation Mechanism for Pt(IV) Anticancer Complexes

, 2016
Electron-Transfer-Driven Trans-Ligand Labilization:  A Novel Activation Mechanism for Pt(IV) Anticancer ...
Piedad del Socorro Murdoch (2966739), Nicole A. Kratochwil (1475092), John A. Parkinson (371195), Zijian Guo (140945), Patrick J. Bednarski (1524088), Peter J. Sadler (1297341)   +5 more
core   +1 more source

Theory of Protein Charge Transfer: Electron Transfer between Tryptophan Residue and Active Site of Azurin [PDF]

, 2022
One reaction step in the conductivity relay of azurin, electron transfer between the Cu-based active site and the tryptophan residue, is studied theoretically and by classical molecular dynamics simulations.
Dmitry V. Matyushov (1291188), Setare, Sarhangi, Dmitry, Matyushov, Setare Mostajabi Sarhangi (5541326)   +3 more
core   +2 more sources

Electron transfer, proton transfer, and molecule transfer in photocatalytic nitrogen fixation

Green Carbon
Photocatalytic nitrogen fixation (PNF) can utilize water and nitrogen gas to synthesize ammonia via the light-driven conversion, significantly contributing to the carbon neutrality goal and mitigating the energy crisis.
Qian Li, Yonghui Shi, Hongxiang Liu, Jiafu Shi, Dong Yang, Zhongyi Jiang   +5 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Identifying the Marcus dimension of electron transfer from ab initio calculations [PDF]

, 2022
The Marcus model forms the foundation for all modern discussion of electron transfer (ET). In this model, ET results in a change in diabatic potential energy surfaces, separated along an ET nuclear coordinate.
Adam, Šrut, Benjamin J., Lear, Vera, Krewald   +2 more
core   +2 more sources

K-shell Analysis Reveals Distinct Functional Parts in an Electron Transfer Network and Its Implications for Extracellular Electron Transfer

Frontiers in Microbiology, 2016
Shewanella oneidensis MR-1 is capable of extracellular electron transfer (EET) and hence has attracted considerable attention. The EET pathways mainly consist of c-type cytochromes, along with some other proteins involved in electron transfer processes ...
Dewu eDing, Ling eLi, Chuanjun eSu, Xiao eSun   +3 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

The Influence of pH on Long-Range Electron Transfer and Proton-Coupled Electron Transfer in Ruthenium-Modified Azurin

Molecules
Long-range electron transfer (ET) is an essential component of all biological systems. Reactions of metalloproteins are important in this context.
Nikta Ghazi, Jeffrey J. Warren
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source