Results 81 to 90 of about 4,359,745 (305)

Electron transport through one and four-channel DNA models

, 2010
DNA molecules possess high density genetic information in living beings, as well as selfassembly and self-recognition properties that make them excellent candidates for many scientific areas, from medicine to nanotechnology.
Lee, Sun-Hee
core  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Electron swarm transport in THF and water mixtures [PDF]

, 2014
The transport coefficients of electrons in mixtures of gaseous water and tetrahydrofuran (THF) are calculated using a multi-term solution of the Boltzmann equation. Electron transport coefficients at room temperature are presented over a range of reduced
Robert E. Robson, Brunger, Michael J., Brunger, Michael J, Robson, Robert E, White, Ronald D., Ronald D. White, Gustavo Garcia, Sasa Dujko, White, Ronald D, Ness, Kevin F., de Urquijo, Jaime, Garcia, Gustavo, Garland, Nathan A., Nathan A. Garland, Petrovic, Zoran Lj., Robson, Robert E., Michael J. Brunger, Dujko, Sasa, Kevin F. Ness, Zoran Lj. Petrović, Garland, Nathan A, Jaime de Urquijo, Ness, Kevin F, Petrovic, Zoran Lj   +23 more
core   +2 more sources

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Coordinating Electron Transport Chains to an Electron Donor

Organic Letters, 2015
Two electron transport chains (2 and 3) featuring two fullerenes with different electron acceptor strengths have been synthesized, characterized, and coordinated to a light harvesting/electron donating zinc porphyrin. Electrochemical assays corroborate the redox gradients along the designed electron transport chains, and complementary absorption and ...
Carmen Villegas, Maximilian Wolf, Damien Joly, Juan Luis Delgado, Dirk M. Guldi, Nazario Martín   +5 more
openaire   +3 more sources

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

The Future of Interurban Passenger Transport: Bringing Citizens Closer Together - 18th International Symposium on Transport Economics and Policy [PDF]

, 2010
The Symposium brought together leading transport researchers from around the world to explore a range of issues under the general theme of “the future for interurban passenger transport”.
OECD, International Transport Forum
core   +1 more source

Negative differential conductance in the electron-transport through copper-rich cuprous oxide thin films

New Journal of Physics, 2019
Copper deposition onto Cu _2 O thin films grown on Au(111) results in the formation of monolayer islands with hexagonal and rhombic shapes, as observed with scanning tunnelling microscopy.
Alexander Gloystein, Christoph Möller, Niklas Nilius   +2 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source