Results 1 to 10 of about 605,158 (291)
Cysteine depletion targets leukemia stem cells through inhibition of electron transport complex II. [PDF]
Blood, 2019 Abstract We have previously demonstrated that oxidative phosphorylation is required for the survival of human leukemia stem cells (LSCs) from patients with acute myeloid leukemia (AML). More recently, we demonstrated that LSCs in patients with de novo AML rely on amino acid metabolism to drive oxidative phosphorylation. Notably, although
Jones CL +10 more
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Electron Transport Chain Complex II Regulates Steroid Metabolism [PDF]
iScience, 2020 Summary: The first steroidogenic enzyme, cytochrome P450-side-chain-cleavage (SCC), requires electron transport chain (ETC) complexes III and IV to initiate steroid metabolic processes for mammalian survival.
Himangshu S. Bose +4 more
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Journal of Photochemistry and Photobiology, 2021 In this work, we have explored a new pH sensitive coumarin based ruthenium(II) complex (R1QC) to mimic the role of P680 in donor side of photosystem II in natural photosynthesis.
Anish Babu Athanas, Swarnalatha Kalaiyar
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Stem Cell Research, 2019 The role of mitochondria in the fate determination of hematopoietic stem and progenitor cells (HSPCs) is not solely limited to the switch from glycolysis to oxidative phosphorylation, but also involves alterations in mitochondrial features and properties,
Claudia Morganti +3 more
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STAR Protocols, 2023 Summary: Mitochondria electron transport chain (ETC) complex II is essential for steroid metabolism. Here, we present a protocol to measure the stability and activity of mitochondria ETC complex II.
Himangshu S. Bose, Nicole E. Doetch
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Redox Biology, 2020 Generation of mitochondrial reactive oxygen species (ROS) is an important process in triggering cellular necrosis and tissue infarction during ischemia-reperfusion (IR) injury. Ischemia results in accumulation of the metabolite succinate. Rapid oxidation
Alexander S. Milliken +2 more
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Chromophore-Assisted Light Inactivation of Mitochondrial Electron Transport Chain Complex II in Caenorhabditis elegans [PDF]
Scientific Reports, 2016 AbstractMitochondria play critical roles in meeting cellular energy demand, in cell death, and in reactive oxygen species (ROS) and stress signaling. Most Caenorhabditis elegans loss-of-function (lf) mutants in nuclear-encoded components of the respiratory chain are non-viable, emphasizing the importance of respiratory function.
Andrew P. Wojtovich +4 more
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Inhibition of electron transport at the cytochrome b6f complex protects photosystem II from photoinhibition [PDF]
FEBS Letters, 2000 Photoinhibition of photosystem II (PS II) activity was studied in thylakoid membranes illuminated in the presence of the inhibitor of the cytochrome b6f complex 2′iodo‐6‐isopropyl‐3‐methyl‐2′,4,4′‐trinitrodiphenylether (DNP‐INT). DNP‐INT was found to decrease photoinhibition.
Anja Krieger‐Liszkay +2 more
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Conducting chiral nickel(
Journal of Materials Chemistry C, 2021 Chiral nickel(ii) bis(dithiolene) complexes based on the mono- and bis-methylated ligands me-dddt and dm-dddt are Mott insulators or band gap semiconductors, with their conductivity modulated by the counter-ion and the number of stereogenic centres.
Alexandre Abhervé +9 more
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Rhodoquinone and Complex II of the Electron Transport Chain in Anaerobically Functioning Eukaryotes [PDF]
Journal of Biological Chemistry, 1995 Many anaerobically functioning eukaryotes have an anaerobic energy metabolism in which fumarate is reduced to succinate. This reduction of fumarate is the opposite reaction to succinate oxidation catalyzed by succinate-ubiquinone oxidoreductase, complex II of the aerobic respiratory chain.
Jaap J. van Hellemond +4 more
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