Results 21 to 30 of about 206,047 (258)

Is impaired energy production a novel insight into the pathogenesis of pyridoxine-dependent epilepsy due to biallelic variants in ALDH7A1?

PLoS ONE, 2021
BackgroundPyridoxine-dependent epilepsy (PDE) is due to biallelic variants in ALDH7A1 (PDE-ALDH7A1). ALDH7A1 encodes α-aminoadipic semialdehyde dehydrogenase in lysine catabolism.
Anastasia Minenkova, Erwin E W Jansen, Jessie Cameron, Rob Barto, Thomas Hurd, Lauren MacNeil, Gajja S Salomons, Saadet Mercimek-Andrews   +7 more
doaj   +1 more source

Inhibition of electron transport at the cytochrome b₆f complex protects photosystem II from photoinhibition [PDF]

FEBS Letters, 2000
Photoinhibition of photosystem II (PS II) activity was studied in thylakoid membranes illuminated in the presence of the inhibitor of the cytochrome b6f complex 2′iodo‐6‐isopropyl‐3‐methyl‐2′,4,4′‐trinitrodiphenylether (DNP‐INT). DNP‐INT was found to decrease photoinhibition.
Liszkay, Anja, Kienzler, Katharina, Johnson, G. N.   +2 more
openaire   +3 more sources

Complex II subunit SDHD is critical for cell growth and metabolism, which can be partially restored with a synthetic ubiquinone analog

BMC Molecular and Cell Biology, 2021
Background Succinate dehydrogenase (Complex II) plays a dual role in respiration by catalyzing the oxidation of succinate to fumarate in the mitochondrial Krebs cycle and transferring electrons from succinate to ubiquinone in the mitochondrial electron ...
Aloka B. Bandara, Joshua C. Drake, David A. Brown   +2 more
doaj   +1 more source

Comparsion of the Effects of Succinate and NADH on Postmortem Metmyoglobin Redcutase Activity and Beef Colour Stability

Journal of Integrative Agriculture, 2014
In two experiments, the effects of succinate and NADH (reduced nicotinamide adenine dinucleotide) on metmyoglobin reductase activity and electron transport chain-linked metmyoglobin reduction were investigated and compared. In experiment 1, metmyoglobin (
Xiao-guang GAO, Zhen-yu WANG, Meng-tian TANG, Chang-wei MA, Rui-tong DAI   +4 more
doaj   +1 more source

Mitochondrial Complex Abundance, Mitophagy Proteins, and Physical Performance in People With and Without Peripheral Artery Disease

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Mitochondrial abnormalities exist in gastrocnemius muscle of people with peripheral artery disease (PAD). Whether abnormalities in mitochondrial biogenesis and autophagy are associated with greater ischemia or walking impairment in PAD is ...
Anna Picca, Stephanie E. Wohlgemuth, Mary M. McDermott, Sunil K. Saini, Sudarshan Dayanidhi, Dongxue Zhang, Shujun Xu, Kate Kosmac, Lu Tian, Luigi Ferrucci, Robert L. Sufit, Emanuele Marzetti, Christiaan Leeuwenburgh   +12 more
doaj   +1 more source

Luseogliflozin preserves the pancreatic beta-cell mass and function in db/db mice by improving mitochondrial function

Scientific Reports, 2022
We aimed to determine the mechanism by which the sodium glucose co-transporter 2 inhibitor, luseogliflozin, preserves pancreatic beta-cell mass and function in db/db mice. Six-week-old db/db mice were fed to standard chow or standard chow containing 0.01%
Yuki Yamauchi, Akinobu Nakamura, Takashi Yokota, Kiyohiko Takahashi, Shinichiro Kawata, Kazuhisa Tsuchida, Kazuno Omori, Hiroshi Nomoto, Hiraku Kameda, Kyu Yong Cho, Toshihisa Anzai, Shinya Tanaka, Yasuo Terauchi, Hideaki Miyoshi, Tatsuya Atsumi   +14 more
doaj   +1 more source

Electron transport chain activity is a predictor and target for venetoclax sensitivity in multiple myeloma

Nature Communications, 2020
Venetoclax monotherapy is effective in 40% of t(11:14) positive multiple myeloma (MM). Here, the authors show that electron transport chain complex I (CI) and complex II (CII) activity predict MM sensitivity to venetoclax, and inhibition of CI with IACS ...
Richa Bajpai, Aditi Sharma, Abhinav Achreja, Claudia L. Edgar, Changyong Wei, Arusha A. Siddiqa, Vikas A. Gupta, Shannon M. Matulis, Samuel K. McBrayer, Anjali Mittal, Manali Rupji, Benjamin G. Barwick, Sagar Lonial, Ajay K. Nooka, Lawrence H. Boise, Deepak Nagrath, Mala Shanmugam   +16 more
doaj   +1 more source

Identifying Site-Specific Superoxide and Hydrogen Peroxide Production Rates From the Mitochondrial Electron Transport System Using a Computational Strategy

Function, 2021
Mitochondrial reactive oxygen species (ROS) play important roles in cellular signaling; however, certain pathological conditions such as ischemia/reperfusion (I/R) injury disrupt ROS homeostasis and contribute to cell death.
Quynh V Duong, Yan Levitsky, Maria J Dessinger, Jasiel O Strubbe-Rivera, Jason N Bazil   +4 more
doaj   +1 more source

Structural Coupling of Extrinsic Proteins with the Oxygen-Evolving Center in Photosystem II

Frontiers in Plant Science, 2016
Photosystem II (PSII), which catalyzes photosynthetic water oxidation, is composed of more than 20 subunits, including membrane-intrinsic and -extrinsic proteins.
Kentaro eIfuku, Takumi eNoguchi
doaj   +1 more source

Melatonin induced changes in photosynthetic efficiency as probed by OJIP associated with improved chromium stress tolerance in canola (Brassica napus L.)

Heliyon, 2020
Chromium toxicity is considered as a major problem for agricultural soil that reduced crop productivity by affecting photosynthetic tissues. Exogenous application of melatonin can alleviate the adverse effects of chromium toxicity on plant growth ...
Ahsan Ayyaz, Misbah Amir, Sarah Umer, Muhammad Iqbal, Hussan Bano, Hafiza Saima Gul, Yamna Noor, Aneela kanwal, Ayesha khalid, Muhammad Javed, Habib R. Athar, Zafar Ullah Zafar, Muhammad Ahsan Farooq   +12 more
doaj   +1 more source