Results 1 to 10 of about 233,572 (253)

An analysis of succinate dehydrogenase B in pleural mesothelioma [PDF]

Discover Oncology
Aim To investigate the expression of succinate dehydrogenase B and its potential as a therapeutic target in pleural mesothelioma (PM). Methods The expression of succinate dehydrogenase B was examined in cell lines using PCR.
Cormac J. Jennings, Stefan J. Marciniak, Giulia Pinton, Doris M. Rassl, Laura Moro, Kenneth J. O’Byrne, Robert C. Rintoul, Stephen P. Finn, Luciano Mutti, Warren Thomas, Steven G. Gray   +10 more
doaj   +6 more sources

Rebalancing mitochondrial dynamics restores succinate dehydrogenase activity and reduces succinate release in hepatocellular carcinoma [PDF]

Journal of Biomedical Science
Background Dysregulated mitochondrial dynamics in cancer cells perturbs mitochondrial function and metabolism and promotes cancer progression. Its impacts on the electron transport chain, oxidative phosphorylation, redox balance, and glycolysis are well ...
Jing-Yiing Wu, Tzu-Ching Chang, Mei-Jen Chen, Shih-Han Cho, Jun-Yang Liou, Cheng-Chin Kuo, Kenneth K. Wu   +6 more
doaj   +3 more sources

Pharmaceutical targeting of succinate dehydrogenase in fibroblasts controls bleomycin-induced lung fibrosis

Redox Biology, 2021
Idiopathic pulmonary fibrosis (IPF) is characterized by excessive deposition of extracellular matrix in the lung with fibroblast-to-myofibroblast transition, leading to chronically compromising lung function and death. However, very little is known about
Yu Huang, Aihua Zhang, Ziyuan Zhou
exaly   +3 more sources

Succinate and succinate dehydrogenase as a «foothold» in the Krebs cycle in critical conditions

Антибиотики и Химиотерапия, 2023
Purpose. Search and presentation of data from experimental and clinical studies reflecting the central role of succinate and succinate dehydrogenase in the regulation of adaptation mechanisms in critical conditions. Material and methods.
Yu. P. Orlov, A. V. Butrov, S. V. Sviridov, V. V. Afanasiev, A. N. Kondratiev, L. M. Tsentsiper, N. V. Govorova, A. I. Kondratiev, G. A. Baytugaeva, E. N. Kakulya   +9 more
doaj   +1 more source

Succinate dehydrogenase‐deficient malignant paraganglioma complicated by succinate dehydrogenase‐deficient renal cell carcinoma

IJU Case Reports, 2022
Introduction SDH Gene mutation is known to be a common cause of pheochromocytoma/paraganglioma and renal cell carcinoma. Here, we report a case of succinate dehydrogenase B‐deficient paraganglioma, which has a high risk of metastasis and recurrence ...
Yoshitomo Yamaguchi, Minato Yokoyama, Akira Takemoto, Yuki Nakamura, Shohei Fukuda, Sho Uehara, Hajime Tanaka, Soichiro Yoshida, Yoh Matsuoka, Yasuhisa Fujii   +9 more
doaj   +1 more source

Hereditary pheochromocytoma/paraganglioma syndrome with a novel mutation in the succinate dehydrogenase subunit B gene in a Japanese family: two case reports

Journal of Medical Case Reports, 2021
Background Pheochromocytoma and paraganglioma caused by succinate dehydrogenase gene mutations is called hereditary pheochromocytoma/paraganglioma syndrome.
Rei Hirose, Yuya Tsurutani, Chiho Sugisawa, Kosuke Inoue, Sachiko Suematsu, Maki Nagata, Naoki Hasegawa, Yukio Kakuta, Masato Yonamine, Kazuhiro Takekoshi, Noriko Kimura, Jun Saito, Tetsuo Nishikawa   +12 more
doaj   +1 more source

TCA cycle tailoring facilitates optimal growth of proton-pumping NADH dehydrogenase-dependent Escherichia coli

Microbiology Spectrum, 2023
The bacterial lifestyle is plastic, requiring transcriptional, translational, and metabolic tailoring for survival. These dynamic cellular processes are energy intensive; therefore, flexible energetics is requisite for adaptive plasticity.
Nikita Goel, Stuti Srivastav, Arjun Patel, Akshay Shirsath, Tushar Ranjan Panda, Malay Patra, Adam M. Feist, Amitesh Anand   +7 more
doaj   +1 more source

Succinate Can Shuttle Reducing Power from the Hypoxic Retina to the O2-Rich Pigment Epithelium

Cell Reports, 2020
Summary: When O2 is plentiful, the mitochondrial electron transport chain uses it as a terminal electron acceptor. However, the mammalian retina thrives in a hypoxic niche in the eye.
Celia M. Bisbach, Daniel T. Hass, Brian M. Robbings, Austin M. Rountree, Martin Sadilek, Ian R. Sweet, James B. Hurley   +6 more
doaj   +1 more source

The Effect of Initial Moisture Content, Packaging and Storage Period on Succinate Dehydrogenase and Cytochrome Oxidase Activity of Soybean Seed

Biotropia: The Southeast Asian Journal of Tropical Biology, 2010
The quality of soybean seed is easily decreased, so that it is difficult to keep them for a long time. The research aims to study the effect of initial moisture content, packaging material and storage period on succinate dehydrogenase and cytochrome ...
Aurellia Tatipata
doaj   +3 more sources

Itaconate and Its Derivatives Repress Early Myogenesis In Vitro and In Vivo

Frontiers in Immunology, 2022
A Krebs cycle intermediate metabolite, itaconate, has gained attention as a potential antimicrobial and autoimmune disease treatment due to its anti-inflammatory effects.
Tae Seok Oh, Damian C. Hutchins, Rabina Mainali, Kevin H. Goslen, Matthew A. Quinn, Matthew A. Quinn   +5 more
doaj   +1 more source