Results 21 to 30 of about 657,635 (323)

Electron transport chain activity is a predictor and target for venetoclax sensitivity in multiple myeloma

Nature Communications, 2020
Venetoclax monotherapy is effective in 40% of t(11:14) positive multiple myeloma (MM). Here, the authors show that electron transport chain complex I (CI) and complex II (CII) activity predict MM sensitivity to venetoclax, and inhibition of CI with IACS ...
Richa Bajpai, Aditi Sharma, Abhinav Achreja, Claudia L. Edgar, Changyong Wei, Arusha A. Siddiqa, Vikas A. Gupta, Shannon M. Matulis, Samuel K. McBrayer, Anjali Mittal, Manali Rupji, Benjamin G. Barwick, Sagar Lonial, Ajay K. Nooka, Lawrence H. Boise, Deepak Nagrath, Mala Shanmugam   +16 more
doaj   +2 more sources

Complex effects of pH on ROS from mitochondrial complex II driven complex I reverse electron transport challenge its role in tissue reperfusion injury [PDF]

, 2020
ABSTRACTGeneration of mitochondrial reactive oxygen species (ROS) is an important process in triggering cellular necrosis and tissue infarction during ischemia-reperfusion (IR) injury. Ischemia results in accumulation of the metabolite succinate. Rapid oxidation of this succinate by mitochondrial complex II (Cx-II) during reperfusion reduces the co ...
Alexander S. Milliken, Chaitanya A. Kulkarni, Paul S. Brookes   +2 more
openalex   +3 more sources

STUDIES ON PHOTOACTIVATED ELECTRON-TRANSPORT SYSTEMS. I. REDUCTION OF HEMIN AND ANTHRAQUINONESULFONATE AS MEDIATED BY PYRIDINIUM IONS AND PHOTOEXCITED RUTHENIUM(II) COMPLEXES [PDF]

Chemistry Letters, 1977
Abstract Photoexcited state of tris(2,2′-bipyridine)ruthenium(II) ion serves as a good reducing agent, if EDTA is present in the solution. Pyridyl radical and 4,4′-bipyridinium cation radical were obtained by this means of photoirradiation, and proved to be useful as mediators for catalytic reduction of Hemin and 9,10-anthraquinone-l ...
Keisuke Takuma, Makoto Kajiwara, Taku Matsuo   +2 more
openalex   +3 more sources

Mitochondrial oxidative stress, cellular damages and stem cell aging in premature aging models with complex II electron transport defect. [PDF]

J Clin Biochem Nutr
Ishii T, Yasuda K, Miyazawa M, Onouchi H, Yanase S, Ishii N.   +5 more
europepmc   +2 more sources

Electron transport in quaternized poly(4-vinylpyridine) films containing pentacyanoferrate(II/III) on electrodes. The influence of the binding type of the electroactive complex

Journal of Electroanalytical Chemistry, 1992
This study is an attempt to investigate how charge transport in thin redox polymer films spin-coated onto glassy carbon electrode surfaces is affected by the way in which the electroactive group is ...
Henrik Larsson, Britta Lindholm, Michael Sharp   +2 more
openalex   +3 more sources

Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species [PDF]

Journal of Cell Science, 2007
Autophagy is a self-digestion process important for cell survival during starvation. It has also been described as a form of programmed cell death. Mitochondria are important regulators of autophagy-induced cell death and damaged mitochondria are often degraded by autophagosomes.
Yongqiang Chen, Eileen McMillan‐Ward, Jiming Kong, Sara J. Israels, Spencer B. Gibson   +4 more
openalex   +4 more sources

The shuttle mechanism of the electron transport by the ruthenium(II) bipyridyl complex-modified bovine adrenodoxin in the steroid hydroxylase

, 2005
Das Hauptziel der vorliegenden Arbeit war, mittels einer Photoreduktion des Adrenodoxins zu zeigen, dass das Eisen-Schwefel-Protein ohne Adrenodoxinreduktase reduziert und damit das Shuttle-Modell für Adrenodoxin überprüft werden kann. Um dieses Hauptziel zu erreichen, wurde eine verkürzte Form des Adrenodoxins, Adx(1-108), mit dem Ru(bpy)2(mbpy ...
A.S. Halavaty
openalex   +3 more sources

P-E3-06 Rhodoquinone and complex II of the electron-transport chain of anaerobically functioning eukaryotes

Progress in Biophysics and Molecular Biology, 1996

openalex   +2 more sources

24-epibrassinolide improved chilled tomato photosynthetic performance by stabilizing electron transport chain and function of photosystem II

Biologia Plantarum, 2022
To explore the protective mechanisms of brassinosteroids in the chill-induced photoinhibition in tomato (Solanum lycopersicum), we studied the effect of foliar sprayed 24-epibrassinolide (EBR, 0.1µM) on the gas exchange, chlorophyll fluorescence ...
W.-H. HU, X.-H. HU, C. LIU, B.-Q. WANG, X.-H. YAN   +4 more
doaj   +1 more source

Electrochemically Driven Photosynthetic Electron Transport in Cyanobacteria Lacking Photosystem II.

Journal of the American Chemical Society, 2022
Light-activated photosystem II (PSII) carries out the critical step of splitting water in photosynthesis. However, PSII is susceptible to light-induced damage.
Christopher Murphy Lewis, Justin D Flory, T. Moore, A. Moore, B. Rittmann, W. Vermaas, César I. Torres, P. Fromme   +7 more
semanticscholar   +1 more source