Results 61 to 70 of about 13,247,852 (336)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Alternative negative weight for simpler hardware implementation of synapse device based neuromorphic system

open access: yesScientific Reports, 2021
Lately, there has been a rapid increase in the use of software-based deep learning neural networks (S-DNN) for the analysis of unstructured data consumption.
Geonhui Han   +7 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Diffusion and Dopant Activation in Germanium: Insights from Recent Experimental and Theoretical Results

open access: yesApplied Sciences, 2019
Germanium is an important mainstream material for many nanoelectronic and sensor applications. The understanding of diffusion at an atomic level is important for fundamental and technological reasons. In the present review, we focus on the description of
E. N. Sgourou   +4 more
doaj   +1 more source

Rubbery Electronics Fully Made of Stretchable Elastomeric Electronic Materials

open access: yesAdvances in Materials, 2019
Stretchable electronics outperform existing rigid and bulky electronics and benefit a wide range of species, including humans, machines, and robots, whose activities are associated with large mechanical deformation and strain.
K. Sim   +3 more
semanticscholar   +1 more source

Novel optoelectronic devices : transition‐metal‐dichalcogenide‐based 2D heterostructures

open access: yes, 2018
Over the past decade, graphene and other 2D materials have attracted much attention in both fundamental studies and potential applications due to their extraordinary properties. In particular, heterostructures based on these van der Waals (vdW) materials
Zheng Liu   +3 more
core   +1 more source

as an Ionic–Electronic Coupled Semiconductor for Switchable Photovoltaic and Neuromorphic Device Applications

open access: yes, 2020
The recent emergence of lead halide perovskites as ionic–electronic coupled semiconductors motivates the investigation of alternative solution‐processable materials with similar modulatable ionic and electronic transport properties.
Nripan Mathews   +21 more
core   +1 more source

Materials and Structural Designs for Neural Interfaces

open access: yes, 2023
Rapid advances in neurotechnology enable bidirectional communication between the nervous system and engineered devices. The precise recording and stimulation of typical target neurons by neural interfaces with adequate materials and structures can ...
Enji Kim   +13 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

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