Results 151 to 160 of about 7,019,216 (255)

UCtracker: A Deep Learning–Based DNA Methylation Model for Noninvasive Diagnosis and Recurrence Surveillance of Urothelial Carcinoma in a Prospective Study

Advanced Science, EarlyView.
We developed UCtracker, a urine DNA methylation–based deep learning model, for noninvasive diagnosis and postoperative surveillance of urothelial carcinoma. UCtracker demonstrates high diagnostic accuracy, robustness at ultralow sequencing depth, early recurrence detection, and dynamic risk‐stratified monitoring of molecular residual disease ...
Shengwei Xiong, Gaojie Li, Yucai Wu, Yuan Liang, Heng Guo, Yu Zhang, Gengyan Xiong, Long Tian, Xin Zhang, Ye Tian, Zhengguo Ji, Bin Guo, Yue Shi, Jian Fan, Zhihua Li, Yanqing Gong, Shiming He, Xuesong Li, Weimin Ci, Liqun Zhou   +19 more
wiley   +1 more source

Observation of Possible Ferroelectric Vortices in Bismuth Square Islands. [PDF]

ACS Nano
Xue SS, Zhong S, Guan D, Liu D, Yu QY, Xi R, Chen X, Sun JC, Zhang Y, Du X, Ning X, Miao T, Hu P, Yang H, Liu X, Liu L, Li Y, Wang S, Liu C, Zhong R, Lu Y, Zheng H, Jia J.   +22 more
europepmc   +1 more source

Engineering‐Modulated Molybdenum Enzymes Strategy for Tumor‐Specific Metabolic‐Immunotherapy

Advanced Science, EarlyView.
Biodegradable molybdenum sulfide nanoparticles were synthesized via a one‐pot strategy to increase molybdenum enzyme activity and thus effectively potentiate anti‐tumor immunity by integrating molybdenum‐based metalloimmunotherapy with hydrogen sulfide gas therapy.
Xiaoxiao Pan, Zifan Pei, Jie Wu, Nan Jiang, Qian Li, Yuqi Yang, Jie Cao, Yechen Huang, Shumin Sun, Qialu Du, Zhicheng Liu, Lin Zhang, Fei Gong, Jinhua Zhou, Liang Cheng   +14 more
wiley   +1 more source

Tungsten-Doped RuO₂ Enables Direct Chloride Adsorption and Accelerated Krishtalik Kinetics for Industrial Chlor-Alkali Electrolysis. [PDF]

Small
Wang Y, Li W, Sun K, Fan Z, Wang R, Xing C, Lu Z, Yang X, Chen J, Wei C, Zhang Y, Huang S, Li L, Xu Y, Guo W, Zhang B.   +15 more
europepmc   +1 more source

Trafficking Deficiency of TMEM175 Variants in Parkinson's Disease Pathogenesis and the Prospects of Precision Medicine

Advanced Science, EarlyView.
This study identifies that the PD‐associated TMEM175‐L156P variant disrupts lysosomal ion channel trafficking by causing aberrant endoplasmic reticulum retention. A “chaperone–agonist” bifunctional small molecule restores TMEM175‐L156P lysosomal localization and channel function, thereby alleviating PD‐relevant cellular phenotypes and highlighting a ...
Ting Luo, Yu He, Shuyao Li, Haoyu Guan, Ruili Cui, Yu Shi, Zhongwen Jiang, Siyu Wang, Xuan Li, Jiyuan Li, Mei Hu, Yupeng Zhou, Beisha Tang, Yanyan Zhang, Zhaobing Gao, Yu Zhou, Zhenhua Liu, Ping Li   +17 more
wiley   +1 more source

High prevalence of Giardia spp. in cats without diarrhea and agreement between diagnostic techniques in the municipality of Londrina, Paraná, Brazil. [PDF]

Vet Res Commun
Aoki LRS, de Souza Rodrigues F, Aoki GCJS, Nino LM, Pyles MS, Dos Santos Pinto M, Sabioni MS, Camargo Neto JAB, Nakamura AA, Bresciani KDS, Felippelli G, Pinto MF.   +11 more
europepmc   +1 more source

Super‐Multiplexed Label‐Free Raman Imaging Uncovers Novel Testicular Metabolic Couplings for Residual Body and Spermatogonial Differentiation

Advanced Science, EarlyView.
Super‐multiplexed Label‐free Raman Imaging (SLRI) enables 2D/3D metabolic mapping of intact Drosophila testes. Moving beyond descriptive morphology, it establishes a multidimensional tool for tissue metabolic remodeling, and offers a generalizable platform for complex tissue analysis, with implications extending to development and disease. ABSTRACT The
Jiaxin Li, Xia Chen, Yujuan Qi, Chen Qiao, Qiuru Huang, Dan Zhao, Weiyi Qian, Li Di, Yi Shi, Xiangqi Hu, Yueyue Shao, Kehan Wang, Zhiyu Tang‐Yang, Hanzhi Zang, Yuwen Du, Anran Dong, Jinxiong Feng, Jiayun Chen, Ying Zheng, Xiaofang Tan, Xiaoyu Zhao, Zhonghua Shi, Bo Zheng, Jun Yu   +23 more
wiley   +1 more source

Adherence to follow-up cervical cancer screening and its predictors among women living with HIV in Moshi municipality, Tanzania: a hospital-based retrospective cohort study (2019-2024). [PDF]

BMJ Open
Doto D, Shirima LJ, Mmbaga B, Kinoko D, Mboya IB, Ughh IHP, Mremi A, Swai P, Mchome B.   +8 more
europepmc   +1 more source

Modulating Calcium Homeostasis via a Biomimetic Scaffold to Rescue Diabetic Ischemic Wounds

Advanced Science, EarlyView.
This strategy addresses impaired microcirculation and loss of extracellular matrix (ECM) guidance in diabetic wound healing. Musc@CP, a nanofibrous dressing combining an ECM‐mimetic chitosan‐pullulan scaffold with muscone, enhances perfusion by attenuating intracellular Ca2+ overload‐associated endothelial dysfunction.
Xiang Zheng, Mingmei Li, Jianjun Jiang, Yongchao Wang, Yaru Jia, Weilun Sun, Yi Yao, Pengli Gao, Linhua Zhang, Qi Guo, Guang Jia, Xing‐Jie Liang, Dunwan Zhu, Jinchao Zhang, Fangzhou Li   +14 more
wiley   +1 more source

Breaking the Photoabsorption-Relaxation Trade-Off: Flat-Band Engineering for Efficient Photothermal Conversion Cocrystals. [PDF]

Small
Ge C, Xie Q, Jiang J, Li Y, Ma X, Wang S, Liu D, Chen T, Song H, Zhang W, Liu Y.   +10 more
europepmc   +1 more source