Deep Learning Prediction of O‐Glycopeptide Tandem Mass Spectra Enhances O‐Glycoproteomics
DeepGPO integrates Transformer and graph neural networks with tailored training strategies, including data augmentation, loss re‐weighting, and pre‐training, to achieve high‐quality O‐glycopeptide MS/MS spectra prediction. The predicted MS/MS spectra are used to localize O‐glycosylation sites from HCD MS/MS data, enhancing O‐glycoproteomics analysis ...
Yu Zong, Yuxin Wang, Liang Qiao
wiley +1 more source
Carbon Dots as Electrostatically Driven Base-Selective Chemical Compilers for Programmable Nucleic Acid Condensation. [PDF]
Hu C +12 more
europepmc +1 more source
Red Blood Cells as Endogenous Biotweezers for Optical Micromanipulation In Vivo
By synergistically integrating the long‐distance manipulation fiber probe (LDMFP) and endogenous red blood cells (RBCs) as biocompatible optical elements, a natural RBC biotweezer was developed for the desired microparticle manipulation and immune cell activation within living vasculature, which might offer an alternative tool for intravital optical ...
Tong Yang +9 more
wiley +1 more source
Lamellar-Paracrystallinity-Controlled Thermal Transport in Polymer Semiconductors. [PDF]
Liu NF +6 more
europepmc +1 more source
A cationic poly(disulfide)‐drug nanoplatform (LA/DexP) was developed to treat experimental autoimmune uveitis (EAU). With potent blood‐retinal barrier penetrability, LA/DexP releases DSP in response to high ROS and scavenges cfDNA to inhibit the cGAS‐STING signaling pathway.
Yuelan Wu +12 more
wiley +1 more source
Geographic variation and factors associated with home-based long-term care utilization across municipalities in Japan. [PDF]
Sakamoto JL.
europepmc +1 more source
Visible‐Light‐Mediated Lewis Acid‐Catalyzed Diradical Hydrogen Atom Transfer Reaction of Enamides
The Lewis acid catalysis was crucial for the success of the DHAT reaction of enamides by lowering the energy of the triplet excited state and modulating the reactivity of the formed diradical intermediate in a carbon‐to‐carbon 1,5‐DHAT and consequent cyclization that allows the functionalization of C(sp3)−H bonds to construct a variety of novel β ...
Yao Huang +5 more
wiley +1 more source
When Octahedra Learn to Be Prisms: Unlocking a Record Deep‑UV NLO Crystal. [PDF]
Gao Q, Wu H, Hu Z, Wang J, Wu Y, Yu H.
europepmc +1 more source
A high‐entropy strategy is developed to break the trade‐off between low melting point and high ionic conductivity in molten salt electrolytes. By incorporating CsBr and LiF into the LiCl‐LiBr‐KBr system, the quinary LiF‐LiCl‐LiBr‐KBr‐CsBr electrolyte achieves a record‐low melting point of 229.5°C while maintaining a high conductivity of 1.19 S cm−1 at ...
Binchao Shi +6 more
wiley +1 more source
Estimating healthy life years without activity limitations using medical claims data in Japan. [PDF]
Nishi M +3 more
europepmc +1 more source

