A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior
Advanced Science, EarlyView.Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li +12 more
wiley +1 more source
Portable and Digital MOX Sensor Electronic Nose with Thermal Modulation: Design, Stability Analysis, and Long-Term Validation. [PDF]
Sensors (Basel)González V +3 more
europepmc +1 more source
Strengthening Constitutive Motifs in Isotropic Fibrous Hydrogel for Exceptional Damage Resistance
Advanced Science, EarlyView.An orientation‐free strategy is reported for fabricating damage‐resistant hydrogels by strengthening constitutive motifs in isotropic fibrous (IF) networks. Through nonsolvent quenching followed by salting‐out, IF networks are generated and their multiscale constituents are subsequently reinforced, yielding dense and crystalline isotropic nanofiber ...
Bolin Wan, Xule Yang, Liju Xu, Dong Qiu
wiley +1 more source
Few-Shot Lung Cancer Classification via Electronic Nose Using Large Language Models: A Multicentre Prospective Study. [PDF]
RespirologyLee MR +10 more
europepmc +1 more source
Retrospective Grid Cells in the Medial Entorhinal Cortex Encode Past Paths During Spatial Navigation
Advanced Science, EarlyView.Retrospective grid cells are identified in the medial entorhinal cortex, with spatial firing patterns that become most grid‐like when activity is projected onto recently traversed locations. Their coding loses spatial precision in darkness and is disrupted during assisted movement, indicating that entorhinal representations incorporate recent path ...
Ruojin Liu +10 more
wiley +1 more source
Characteristic Constituents of Maocangzhu and Beicangzhu Revealed Using Electronic Nose, Electronic Tongue, HS-GC-IMS, and UPLC-Orbitrap Technologies. [PDF]
MoleculesZhang H, Qu Z, Wang F, Han Y, Li Y.
europepmc +1 more source
Advanced Science, EarlyView.PCSK9 upregulation in cerebrovascular endothelial cells and microglia destabilizes the Aβ transporter LRP1, while TRIB3‐associated autophagy blockade further limits intracellular Aβ degradation. A RAP‐modified tea‐polyphenol nanoparticle co‐delivers siPCSK9 and siTRIB3 to restore LRP1‐mediated Aβ efflux and autophagy‐dependent degradation, reducing Aβ ...
Jie Miao +8 more
wiley +1 more source
Neurophysiological Responses to Inhalation of <i>Osmanthus fragrans</i> Volatiles: A Combined Electronic Nose and Electroencephalogram (EEG) Study on Concentration-Dependent Effects. [PDF]
Plants (Basel)Hong SJ +10 more
europepmc +1 more source
Advanced Science, EarlyView.Existing machine learning potentials remain limited in their ability to generalize across the broad chemical and structural variability of C–S–H. Here, a representative DFT‐labeled dataset is constructed through large‐scale model generation, redundancy‐controlled screening, first‐principles optimization, and targeted sampling of non‐equilibrium ...
Yunjian Li +4 more
wiley +1 more source
Multi-Granularity Domain Adversarial Learning for Cross-Domain Tea Classification Using Electronic Nose Signals. [PDF]
FoodsWang X, Gu Y.
europepmc +1 more source