Microfluidic-based electrically driven particle manipulation techniques for biomedical applications. [PDF]
Wang J+9 more
europepmc +1 more source
DNA binding of metal complexes is impacted by their chirality. The use of chiral HPLC to resolve a library of 18 ruthenium and osmium polypyridyl DNA probes is described. Separation is found to be influenced by the nature of the polypyridyl ligands with enantioselection improving with increasing conjugation of the π‐system.
Simon N. Smith+5 more
wiley +1 more source
Proliferative glomerulonephritis with monoclonal immunoglobulin deposits masquerading as renal-specific thrombotic microangiopathy. [PDF]
Duxbury HJ+3 more
europepmc +1 more source
Abstract The characterization of the impurities of pharmaceutical monoclonal antibodies (mAbs) is crucial for their function and safety. Capillary zone electrophoresis (CZE) is one of the most efficient tools to separate charge variants of mAbs; however, peak characterization remains difficult, since the hereby used background electrolytes (BGEs) are ...
Alisa Höchsmann+4 more
wiley +1 more source
Abstract Heparan sulphates (HSs), a specific class of glycosaminoglycans (GAGs), are important participants of cellular signalling. Analytical characterization of GAGs requires a complex sample preparation workflow. Although a detailed stability and recovery study is available for the chondroitin sulphate GAG class, the literature concerning HS is ...
Domonkos Pál+2 more
wiley +1 more source
Electrokinetic Chromatography-based Micro Methods for Separation and Physiochemical Characterization of Very Hydrophobic Pharmaceuticals. [PDF]
Minkner R, Wätzig H.
europepmc +1 more source
Enhanced Separation of Extracellular Vesicles Using Capillary Isotachophoresis With Spacer Compounds
ABSTRACT Extracellular vesicles (EVs) are pivotal in numerous physiological and pathological processes, such as immune responses, viral pathogenesis, pregnancy, cardiovascular diseases, and cancer progression. Their capacity to influence complex intracellular pathways highlights their therapeutic potential in addressing various conditions, including ...
Milan Pieter Paul de Putter+4 more
wiley +1 more source
Nuclear Multi-Microsatellite Marker Profiling Provides Clues to Molecular Genetic Diversity in Culture-Based Caspian Beluga Sturgeon (Huso huso) Brood Stocks: Ecological Mirror for Restoration. [PDF]
Moghim M+4 more
europepmc +1 more source
A brief history and future directions of dielectrophoretic filtration: A review
Abstract Dielectrophoresis (DEP) is an electrokinetic effect first studied in the early 20th century. Since then, DEP has gained significant interest in research, owing to its ability to solve particle separation problems in various industries. Dielectrophoretic filtration (DEP filtration) is a separation method using DEP to filter a wide range of ...
Mary Clare O'Donnell+2 more
wiley +1 more source
Rapid quantitative analysis of double-stranded plasmid DNA with capillary gel electrophoresis for applications in quality control and radiation research. [PDF]
Hahn MB.
europepmc +1 more source