Results 221 to 230 of about 216,637 (322)

Microfluidic-based electrically driven particle manipulation techniques for biomedical applications. [PDF]

open access: yesRSC Adv
Wang J   +9 more
europepmc   +1 more source

Chiral Resolution of Transition Metal Polypyridyl Complexes via HPLC As a Gateway to Enantiopure DNA Targeting Probes

open access: yesEuropean Journal of Inorganic Chemistry, Volume 28, Issue 11, April 9, 2025.
DNA binding of metal complexes is impacted by their chirality. The use of chiral HPLC to resolve a library of 18 ruthenium and osmium polypyridyl DNA probes is described. Separation is found to be influenced by the nature of the polypyridyl ligands with enantioselection improving with increasing conjugation of the π‐system.
Simon N. Smith   +5 more
wiley   +1 more source

Charge variant analysis of monoclonal antibodies by CZE‐MS using a successive multiple ionic‐polymer layer coating based on diethylaminoethyl‐dextran

open access: yesELECTROPHORESIS, Volume 46, Issue 5-6, Page 279-289, March 2025.
Abstract The characterization of the impurities of pharmaceutical monoclonal antibodies (mAbs) is crucial for their function and safety. Capillary zone electrophoresis (CZE) is one of the most efficient tools to separate charge variants of mAbs; however, peak characterization remains difficult, since the hereby used background electrolytes (BGEs) are ...
Alisa Höchsmann   +4 more
wiley   +1 more source

Investigation of sample handling steps for accurate heparan sulphate disaccharide analysis using HPLC–MS

open access: yesELECTROPHORESIS, EarlyView.
Abstract Heparan sulphates (HSs), a specific class of glycosaminoglycans (GAGs), are important participants of cellular signalling. Analytical characterization of GAGs requires a complex sample preparation workflow. Although a detailed stability and recovery study is available for the chondroitin sulphate GAG class, the literature concerning HS is ...
Domonkos Pál   +2 more
wiley   +1 more source

Enhanced Separation of Extracellular Vesicles Using Capillary Isotachophoresis With Spacer Compounds

open access: yesELECTROPHORESIS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are pivotal in numerous physiological and pathological processes, such as immune responses, viral pathogenesis, pregnancy, cardiovascular diseases, and cancer progression. Their capacity to influence complex intracellular pathways highlights their therapeutic potential in addressing various conditions, including ...
Milan Pieter Paul de Putter   +4 more
wiley   +1 more source

A brief history and future directions of dielectrophoretic filtration: A review

open access: yesELECTROPHORESIS, EarlyView.
Abstract Dielectrophoresis (DEP) is an electrokinetic effect first studied in the early 20th century. Since then, DEP has gained significant interest in research, owing to its ability to solve particle separation problems in various industries. Dielectrophoretic filtration (DEP filtration) is a separation method using DEP to filter a wide range of ...
Mary Clare O'Donnell   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy