Results 241 to 250 of about 820,083 (349)

Mass spectrometry-based top-down proteomics for proteoform profiling of protein coronas. [PDF]

Nat Protoc
Sadeghi SA, Fang F, Tabatabaeian Nimavard R, Wang Q, Zhu G, Saei AA, Sun L, Mahmoudi M.   +7 more
europepmc   +1 more source

Gel Electrophoretic Detection of Black Market ACE‐031

Drug Testing and Analysis, EarlyView.
This article presents a study on black market ACE‐031 products and their detection by gel‐electrophoresis and Western blotting. Of the 14 tested products, only 12 contained an ACVR2B‐immunoreactive protein. However, mass spectrometry revealed that the products did not contain the ACVR2B‐Fc fusion protein ACE‐031 but instead the full‐length human ...
Christian Reichel, Thomas Filip, Günter Gmeiner, Mario Thevis   +3 more
wiley   +1 more source

Development and Application of an In-Capillary CE-DAD Method for the Inhibitory Screening of Natural Extracts Towards Acetylcholinesterase Enzyme. [PDF]

Metabolites
Rinaldi F, Salerno S, Frigoli E, De Soricellis G, Brusotti G, Negri S, Radice M, Merlo F, Speltini A, Cena H, Calleri E.   +10 more
europepmc   +1 more source

Detection of a Single Microdose of Testosterone and Recombinant EPO in Healthy Volunteers

Drug Testing and Analysis, EarlyView.
Exogenous T was detected with IRMS regardless of T/E elevation—high serum T indicative for IRMS. rhEPO was detected in urine for 72 h in ITP and CP, and Tasso showed less sensitivity than previous DBS devices tested. ABSTRACT Doping with testosterone (T) and erythropoietin (EPO) in low doses (micro‐doping) is a challenge to detect.
Carmel Heiland, Oscar Hopcraft, Mats Johanson, Anton Pohanka, Mikael Lehtihet, Lena Ekström   +5 more
wiley   +1 more source

Identification of Candidate Blood Biomarkers of Recombinant Human Erythropoietin Administration Using Targeted Polar Metabolomics by HILIC‐MS/MS

Drug Testing and Analysis, EarlyView.
Using targeted HILIC‐MS/MS metabolomics, inosine and hypoxanthine were identified as potential biomarkers of EPO administration. Their consistent and sensitive plasma responses highlight their promise for inclusion in the Athlete Biological Passport (ABP), warranting further investigation to enhance anti‐doping detection strategies. ABSTRACT Increasing
Olivier Salamin, Lejla Ramic, Raul Nicoli, Serge Rudaz, Davy Guillarme, Tiia Kuuranne   +5 more
wiley   +1 more source

Multiclonal Profiling of FLT3-ITD in AML Using MinION Sequencing: A Tailored Clustering Approach to Enhance Subclonal Detection. [PDF]

Onco Targets Ther
Martínez-Serra J, Alonso-Carballo A, Horrillo Á, Gómez P, Vögler O, Gutiérrez A, Sampol A.   +6 more
europepmc   +1 more source

Biomass‐Derived Porous Crystalline Calcium‐Silicates Synthesized from Chicken Eggshell Waste Using Organic Amine Templates: A Case Study for Potential Hemostatic Application

European Journal of Inorganic Chemistry, EarlyView.
Calcium silicate materials are synthesized using eggshell waste as a sustainable calcium source. Quaternary ammonium salts are employed as key structure‐directing agents, favoring the formation of the clay‐like mineral rhodesite with a significantly higher surface area than previously reported. The hemostatic performance of the synthesized materials is
Guilherme de Paula Guarnieri, Oscar Antonio Niño Santisteban, Erick Paiva Cancella, Eduardo Ribeiro de Azevedo, Ivana Conte Cosentino, Lucildes Pita Mercuri, Marcelo Larami Santoro, Moacir Fernandes de Godoy, José Geraldo Nery   +8 more
wiley   +1 more source

Advancing in ovo egg sexing through molecular sex identification of chick embryos using LAMP and RPA assays. [PDF]

Sci Rep
Van Der Hofstadt M, l'Helgoualch N, Houot-Cernettig J, Galindo T, Manso T, Martins PGA, Huguenin J, Espeut J, Molina F, Van TNN.   +9 more
europepmc   +1 more source

β‐Lactoglobulin Stabilized Emulsions: A Small Angle X‐Ray Scattering Study on Stability, Ageing, and Thermal Effects

European Journal of Lipid Science and Technology, EarlyView.
This study investigates the structural differences in β‐lactoglobulin stabilized emulsions (BLGem) under various conditions (fresh, aged, and aged at high temperature) using small angle x‐ray scattering (SAXS). The graph shows change in intensity over a range of scattering vectors, with visual evidence of emulsions at different conditions.
Rini P. Ravindranathan, Jon Otto Fossum, Matti Knaapila, Kenneth D. Knudsen   +3 more
wiley   +1 more source