Results 61 to 70 of about 226,631 (305)

New Insights into Atonic Postpartum Hemorrhage: Animal Model Construction Based on Placental Nanodelivery Systems

open access: yesAdvanced Healthcare Materials, EarlyView.
This study develops a placenta‐targeted nanodelivery system co‐loading HMGB1 protein and the NLRP3 agonist nigericin to establish an animal model of atonic postpartum hemorrhage. The model accurately recapitulates clinical phenotypes, including prolonged labor and uterine contractility dysfunction, while revealing inflammatory activation in placental ...
Jiangxue Qu   +10 more
wiley   +1 more source

Evaluating the Antiviral Efficacy of Encapsulated PKC Inhibitor BIM‐I against influenza A Virus Infection

open access: yesAdvanced Healthcare Materials, EarlyView.
This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement   +12 more
wiley   +1 more source

Photochromic spiropyran monolithic polymers: Molecular photo-controllable electroosmotic pumps for micro-fluidic devices [PDF]

open access: yes, 2010
A novel photo-controllable micro-fluidic electroosmotic pump based on spiropyran monolithic polymers is presented here for the first time. Photochromic monolithic scaffolds have been synthesised within poly(tetrafluoroethylene) coated fused silica ...
Abele, Silvija   +9 more
core   +1 more source

An Ultrapotent, Ultraeconomical, Antifreeze Polypeptide

open access: yesAdvanced Materials, EarlyView.
Simple and inexpensive polypeptides composed of random copolymers of alanine and glutamic acid are effective antifreezes for applications in foods and biomedicine. The polypeptides, inspired by natural extremophile proteins, inhibit the growth of large ice crystals and prevent damage to sensitive biologics.
Thomas J. McPartlon   +5 more
wiley   +1 more source

Microchip Capillary Electrophoresis [PDF]

open access: yes, 2014
For the study of neuromodulation in Cancer borealis we have designed a microfluidic device to separate and detect bioamine concentrations with a high temporal resolution.
Hardy, Scott   +2 more
core   +1 more source

Novel microstructures and technologies applied in chemical analysis techniques [PDF]

open access: yes, 1997
Novel glass and silicon microstructures and their application in chemical analysis are presented. The micro technologies comprise (deep) dry etching, thin layer growth and anodic bonding.
Burger, G.J.   +5 more
core   +3 more sources

Light‐Activated Micromotors in Air Propelled by Thermal Convection

open access: yesAdvanced Materials, EarlyView.
Near‐infrared‐driven micromotors in air can overcome gravity and generate convective motion by a light‐induced thermal mechanism driven by a temperature gradient in the air caused by the interaction of the gold nanoparticles present on the surface of ZnO and NIR irradiation.
Pedro Mena‐Giraldo   +6 more
wiley   +1 more source

Separation of Chlorins and Carotenoids in Capillary Electrophoresis [PDF]

open access: yes, 2017
The present study reports the investigation of capillary electrophoresis (CE) for the separation of the photosynthetic pigments (chlorophyll derivatives as well as carotenoids) together. Various CE methods, such as micellar electrokinetic chromatography,
Belin, Gamze Kavran, Gülaçar, Fazil O.
core  

Capillary Electrophoresis of DNA [PDF]

open access: yesCurrent Protocols in Molecular Biology, 1999
AbstractCapillary electrophoresis (CE) is an alternative to conventional slab gel electrophoresis for the separation of DNA fragments. CE offers a number of advantages over slab gel separations in terms of speed, resolution, sensitivity, and data handling. Separation times are generally only a few minutes and the DNA is detected either by UV absorption
Smith, Alan, Nelson, Robert J.
openaire   +4 more sources

LDI, A Lipid Droplet Inhibitor, Disrupts Lipid Accumulation and Modulates Hepatic Lipid Profiles in Fatty Liver

open access: yesAdvanced Materials, EarlyView.
The lipid droplet inhibitor (LDI), templated with large‐pore mesoporous silica and functionalized with PKCα C1A and lipase, targets lipid degradation in fatty liver. The LDI maintains stable association with lipid droplets, thereby suppressing their formation and expansion.
Seunghee Kim   +12 more
wiley   +1 more source

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