Results 231 to 240 of about 1,452,728 (336)

A freely available gel electrophoresis laboratory manual and course materials. [PDF]

J Microbiol Biol Educ
Telfah R, Patrick K, Shultz JL.
europepmc   +1 more source

Bilirubin Sensing Using Organic Electrochemical Transistors: Role of Gate Materials and Operational Parameters

Advanced Healthcare Materials, EarlyView.
This study explores PEDOT:PSS‐based OECTs as sensitive bilirubin sensors, revealing that polarizable gate electrodes (Au, Pt, glassy carbon) enable detection while non‐polarizable Ag/AgCl gates suppress response. Operational parameters modulate current direction, suggesting complex interfacial dynamics.
Yunjia Song, Sihui Xu, Onur Parlak
wiley   +1 more source

Mechanistic insights into circularization via <i>Anabaena</i> group I intron-based scarless circular RNA. [PDF]

Mol Ther Nucleic Acids
Fan B, Liu S, Xu Y, Ma X, Qi W, Miao L, Liu L, Du S, Lin J.   +8 more
europepmc   +1 more source

A Modular Perfusion Bioreactor Platform for Simulating Bone Regeneration and Fracture Healing: Integrating Mechanical Loading and Dual Perfusion for Advanced In Vitro Models

Advanced Healthcare Materials, EarlyView.
A modular bioreactor platform was developed in order to replicate bone homeostasis and pathology, thereby integrating mechanical loading, dynamic perfusion, and a 3D‐printed microfluidic chamber. With precise control of environmental parameters and dual perfusion for composite tissue models, the system enhances physiological relevance for studying bone
Moritz Pfeiffenberger, Alexandra Damerau, Johannes Plank, Adel Ahmed, Mario Thiele, Jan Saam, Paula Hoff, Timo Gaber, Frank Buttgereit   +8 more
wiley   +1 more source

Magnetic Resonance Imaging‐Based Quantification of Endosomal Escape Using Iron Oxide Nanoparticle‐Loaded Lipid Nanoparticles

Advanced Healthcare Materials, EarlyView.
The therapeutic efficacy of lipid nanoparticle(LNP)‐based drugs depends on endosomal escape. However, few methods are available for quantifying the efficiency of endosomal escape in vivo. Herein, a novel method for quantifying the endosomal escape efficiency index using magnetic resonance imaging is introduced.
Somin Lee, Jeongbin Park, Han Na Jung, Shengjun Li, Zhijun Lin, Hyung‐Jun Im   +5 more
wiley   +1 more source

Unveiling Rare Hemoglobinopathies: Hematologic Characterization of Double Heterozygous Hb D and Hb E With Beta-Thalassemia-A Case Report. [PDF]

Case Rep Hematol
Minhas AM, Eiman H, Iqbal J, Imran A, Chughtai AS.   +4 more
europepmc   +1 more source

Development of a Modular Ribonucleoprotein Complex as a General Strategy to Deliver RNAi Therapeutics

Advanced Healthcare Materials, EarlyView.
A modular and customizable RNAi therapeutics delivery platform composed of a pseudosymmetric human RNA binding protein‐siRNA complex (SmiRNP) is developed. By fusing a targeting module and an endosomal escape peptide onto the delivery platform, SmiRNP successfully delivered siRNA to silence the KRAS oncogene in a colorectal carcinoma cell line, leading
Nok Yin Tam, Xiaoqi Wang, Grace Chung Yan Chan, Wai Po Kong, Wai Yin Chau, Xiuqiong Fu, Kwok‐Yin Wong, Hong Lok Lung, Zhi‐Ling Yu, Wei Shen Aik   +9 more
wiley   +1 more source

DIFFERENTIAL TITRATION BY MEANS OF PAPER ELECTROPHORESIS AND THE STRUCTURE OF HUMAN HEMOGLOBINS

, 1954
I. Herbert Scheinberg, Ruth S. Harris, Joan L. Spitzer   +2 more
openalex   +1 more source

Selective Lipolysis by Photoactivation of Chaperone‐Mediated Autophagy Using Adipocyte Membrane‐Coated Nanoparticle in Hydrogel

Advanced Materials, EarlyView.
Adipocyte membrane‐coated nanoparticles loaded with rosiglitazone in hydrogel offer an alternative approach to conventional obesity treatments. This system selectively targets adipocytes, inducing lipolysis by activating chaperone‐mediated autophagy through mild photothermal stimulation.
Jaehyun Choi, Junho Byun, Dongyoon Kim, Qiaoyun Li, Dongun Jin, Yeong‐jin Choi, Ho Sang Jung, Jaiwoo Lee, Yu‐Kyoung Oh   +8 more
wiley   +1 more source

Correction: A Mg²⁺-dependent high-yield method for extracting high-molecular-weight genomic DNA from a single planarian specimen. [PDF]

BMC Genomics
Li A, Sun B, Zhang Y, Yu P, Qu J, Deng H, Pang Q, Yang F.   +7 more
europepmc   +1 more source