Results 61 to 70 of about 6,006 (253)

Endogenous mammalian lectin localized extracellularly in lung elastic fibers. [PDF]

open access: yes, 1984
An affinity-purified antibody preparation raised against a beta-galactoside-binding lectin from bovine lung was used to localize a similar lectin in rat lung by immunofluorescence and by electron microscopy after on-grid staining visualized with ...
Barondes, SH   +2 more
core   +3 more sources

Activity Profiling of Nitro‐Substituted Di(Hetero)Aryl 1,3,4‐ and 1,2,4‐Oxadiazoles: Antimicrobial, Cholinesterase Inhibition and Antioxidant Potential

open access: yesArchiv der Pharmazie, Volume 359, Issue 1, January 2026.
Novel nitro‐substituted diaryl 1,3,4‐ and 1,2,4‐oxadiazoles were synthesised via molecular hybridisation of bioactive heterocycles. Selected derivatives exhibited potent antimicrobial activity, including against Mycobacterium tuberculosis and Staphylococcus aureus, and cholinesterase inhibitory activity, with promising selectivity.
Enikő Šikorová   +9 more
wiley   +1 more source

Vectorially Imprinted Hybrid Nanofilm for Acetylcholinesterase Recognition [PDF]

open access: yes, 2015
Effective recognition of enzymatically active tetrameric acetylcholinesterase (AChE) is accomplished by a hybrid nanofilm composed of a propidium-terminated self-assembled monolayer (Prop-SAM) which binds AChE via its peripheral anionic site (PAS) and an
Dechtrirat, Decha   +5 more
core   +1 more source

Novel Sulfonylhydrazones With Sulfonate Ester Framework: Promising Dual Inhibitors of AChE and hCAs

open access: yesBiotechnology and Applied Biochemistry, Volume 72, Issue 6, Page 1752-1762, December 2025.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder that affects millions of individuals worldwide. Treatment strategies for AD vary depending on cognitive and behavioral symptoms, with cholinergic replacement therapy using acetylcholinesterase (AChE) inhibitors being one of the primary approaches.
Cansu Öztürk   +3 more
wiley   +1 more source

Acetylcholinesterase Inhibition and Antioxidant Activity of N-trans-Caffeoyldopamine and N-trans-Feruloyldopamine

open access: yesScientia Pharmaceutica, 2018
Phenolic acids and their derivatives found in nature are well-known for their potential biological activity. In this study, two amides derived from trans-caffeic/ferulic acid and dopamine were synthesized and characterized by Fourier-transform infrared ...
Muamer Dizdar   +4 more
doaj   +1 more source

An electrocyte‐inspired moisture‐driven electricity generator for self‐sustained water electrolysis

open access: yesDroplet, Volume 4, Issue 4, October 2025.
Inspired by the electric eel's electrocytes, a Janus hygroscopic film mediated by a pioneer continuous interphase is designed to significantly alleviates the ion migration resistance, achieving an ultrahigh current of 150 µA and maintaining a voltage of 0.8 V for over 1000 h.
Quanmao Wei   +9 more
wiley   +1 more source

Francisco Salva's Electric Telegraph

open access: yes, 2010
This article takes a look at the life and accomplishments of Francisco Salva of Spain, including his work with an electric telegraph system. The author states that information herein is based on the original report and some practical demonstrations that ...
Pérez Yuste, Antonio
core   +1 more source

Synthesis and biological evaluation of benzochromenopyrimidinones as cholinesterase inhibitors and potent antioxidant, non-hepatotoxic agents for Alzheimer’s disease [PDF]

open access: yes, 2016
We report herein the straightforward two-step synthesis and biological assessment of novel racemic benzochromenopyrimidinones as non-hepatotoxic, acetylcholinesterase inhibitors with antioxidative properties.
Alexandre Bonet   +19 more
core   +4 more sources

One-Pot Synthesis of NEMP, a VX Surrogate, and Reactivation of NEMP-Inhibited Electrophorus Eel Acetylcholinesterase by Current Antidotes

open access: yes, 2018
The use of nerve agents, organophosphorus compounds which irreversibly inhibit acetylcholinesterase, in conflicts and terrorism has gained renewed geopolitical status in recent years.
S. Cavalcante   +6 more
semanticscholar   +1 more source

Phencyclidine (PCP) blocks glutamate-activated postsynaptic currents [PDF]

open access: yes, 1985
Phencyclidine (PCP) was tested on the metathoracic tibialis muscles of Locusta migratoria. In physiological solution, the peak amplitude of the excitatory postsynaptic currents (EPSCs) evoked by nerve stimulation was linearly related to membrane ...
M. Idriss   +25 more
core   +2 more sources

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