Results 61 to 70 of about 6,006 (253)
Endogenous mammalian lectin localized extracellularly in lung elastic fibers. [PDF]
An affinity-purified antibody preparation raised against a beta-galactoside-binding lectin from bovine lung was used to localize a similar lectin in rat lung by immunofluorescence and by electron microscopy after on-grid staining visualized with ...
Barondes, SH +2 more
core +3 more sources
Novel nitro‐substituted diaryl 1,3,4‐ and 1,2,4‐oxadiazoles were synthesised via molecular hybridisation of bioactive heterocycles. Selected derivatives exhibited potent antimicrobial activity, including against Mycobacterium tuberculosis and Staphylococcus aureus, and cholinesterase inhibitory activity, with promising selectivity.
Enikő Šikorová +9 more
wiley +1 more source
Vectorially Imprinted Hybrid Nanofilm for Acetylcholinesterase Recognition [PDF]
Effective recognition of enzymatically active tetrameric acetylcholinesterase (AChE) is accomplished by a hybrid nanofilm composed of a propidium-terminated self-assembled monolayer (Prop-SAM) which binds AChE via its peripheral anionic site (PAS) and an
Dechtrirat, Decha +5 more
core +1 more source
Novel Sulfonylhydrazones With Sulfonate Ester Framework: Promising Dual Inhibitors of AChE and hCAs
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder that affects millions of individuals worldwide. Treatment strategies for AD vary depending on cognitive and behavioral symptoms, with cholinergic replacement therapy using acetylcholinesterase (AChE) inhibitors being one of the primary approaches.
Cansu Öztürk +3 more
wiley +1 more source
Phenolic acids and their derivatives found in nature are well-known for their potential biological activity. In this study, two amides derived from trans-caffeic/ferulic acid and dopamine were synthesized and characterized by Fourier-transform infrared ...
Muamer Dizdar +4 more
doaj +1 more source
An electrocyte‐inspired moisture‐driven electricity generator for self‐sustained water electrolysis
Inspired by the electric eel's electrocytes, a Janus hygroscopic film mediated by a pioneer continuous interphase is designed to significantly alleviates the ion migration resistance, achieving an ultrahigh current of 150 µA and maintaining a voltage of 0.8 V for over 1000 h.
Quanmao Wei +9 more
wiley +1 more source
Francisco Salva's Electric Telegraph
This article takes a look at the life and accomplishments of Francisco Salva of Spain, including his work with an electric telegraph system. The author states that information herein is based on the original report and some practical demonstrations that ...
Pérez Yuste, Antonio
core +1 more source
Synthesis and biological evaluation of benzochromenopyrimidinones as cholinesterase inhibitors and potent antioxidant, non-hepatotoxic agents for Alzheimer’s disease [PDF]
We report herein the straightforward two-step synthesis and biological assessment of novel racemic benzochromenopyrimidinones as non-hepatotoxic, acetylcholinesterase inhibitors with antioxidative properties.
Alexandre Bonet +19 more
core +4 more sources
The use of nerve agents, organophosphorus compounds which irreversibly inhibit acetylcholinesterase, in conflicts and terrorism has gained renewed geopolitical status in recent years.
S. Cavalcante +6 more
semanticscholar +1 more source
Phencyclidine (PCP) blocks glutamate-activated postsynaptic currents [PDF]
Phencyclidine (PCP) was tested on the metathoracic tibialis muscles of Locusta migratoria. In physiological solution, the peak amplitude of the excitatory postsynaptic currents (EPSCs) evoked by nerve stimulation was linearly related to membrane ...
M. Idriss +25 more
core +2 more sources

