Results 71 to 80 of about 6,006 (253)

Design, Synthesis, In Vitro, and In Silico Studies of 5‐(Diethylamino)‐2‐Formylphenyl Naphthalene‐2‐Sulfonate Based Thiosemicarbazones as Potent Anti‐Alzheimer Agents

open access: yesArchiv der Pharmazie, Volume 358, Issue 7, July 2025.
A novel series of 4‐(diethylamino)salicylaldehyde‐based thiosemicarbazone derivatives 5(a–u) were synthesized and screened for their potential against Alzheimer's disease, by testing for their inhibitory effects against cholinesterases (AChE and BChE) and monoaminoxidase A (MAO‐A) and B (MAO‐A).
Urva Farooq   +11 more
wiley   +1 more source

Ion channels: structural basis for function and disease. [PDF]

open access: yes, 1996
Ion channels are ubiquitous proteins that mediate nervous and muscular function, rapid transmembrane signaling events, and ionic and fluid balance. The cloning of genes encoding ion channels has led to major strides in understanding the mechanistic basis
Goldstein, SA
core   +1 more source

Skin mucus proteome map of European sea bass (Dicentrarchus labrax) [PDF]

open access: yes, 2015
Author's accepted version (post-print).This is the peer reviewed version of the following article: Cordero, H., Brinchmann, M.F., Cuesta, A., Meseguer, J. & Esteban, M.A. (2015).
Brinchmann, Monica Fengsrud   +4 more
core   +3 more sources

Evaluation of Antioxidant and Enzyme Inhibition Properties of Siran Propolis: Correlations With Phenolic Content Determined by LC–MS/MS

open access: yesFood Science &Nutrition, Volume 13, Issue 7, July 2025.
The ethanolic extract of Şiran propolis exhibited strong antioxidant activity and inhibited α‐glycosidase, AChE, and human carbonic anhydrase isozymes I and II. High levels of phenolic acids, especially p‐coumaric and ferulic acids, correlated with its bioactivity.
Neslihan Balci   +3 more
wiley   +1 more source

Characterization of Monoclonal Antibodies that Strongly Inhibit Electrophorus Electricus Acetylcholinesterase [PDF]

open access: yesEuropean Journal of Biochemistry, 1995
In this study, we describe three different monoclonal antibodies (mAbs Elec‐403, Elec‐408, and Elec‐410) directed against Electrophorus electricus acetylcholinesterase (AChE) which were selected as inhibitors for this enzyme. Two of these antibodies (Elec‐403 and Elec‐410), recognized overlapping but different epitopes, competed with snake venom toxin ...
M H, Remy, Y, Frobert, J, Grassi
openaire   +2 more sources

Unique patterns of transcript and miRNA expression in the South American strong voltage electric eel (Electrophorus electricus)

open access: yesBMC Genomics, 2015
BackgroundWith its unique ability to produce high-voltage electric discharges in excess of 600 volts, the South American strong voltage electric eel (Electrophorus electricus) has played an important role in the history of science.
L. Traeger   +15 more
semanticscholar   +1 more source

Effect of aerial O-2 partial pressure on bimodal gas exchange and air-breathing behaviour in Trichogaster leeri [PDF]

open access: yes, 2007
© The Company of Biologists Ltd 2007The effects of experimental alterations of aerial O2 partial pressure (PO2,air) on bimodal gas exchange and airbreathing behaviour were investigated in the aquatic airbreathing fish Trichogaster leeri in normoxic water.
Alton, L., Seymour, R., White, C.
core   +3 more sources

Light‐Activated Pharmacological Tools for Exploring the Cholinergic System

open access: yesMedicinal Research Reviews, Volume 45, Issue 4, Page 1251-1274, July 2025.
ABSTRACT Cholinergic transmission plays a critical role in both the central and peripheral nervous systems, affecting processes such as learning, memory, and inflammation. Conventional cholinergic drugs generally suffer from poor selectivity and temporal precision, leading to undesired effects and limited therapeutic efficacy. Photopharmacology aims to
Alessio Colleoni   +5 more
wiley   +1 more source

The Astonishing Behavior of Electric Eels

open access: yesFrontiers in Integrative Neuroscience, 2019
The remarkable physiology of the electric eel (Electrophorus electricus) made it one of the first model species in science. It was pivotal for understanding animal electricity in the 1700s, was investigated by Humboldt and Faraday in the 1800s, was ...
Kenneth C. Catania
doaj   +1 more source

Monoclonal antibodies to the cells of a regenerating limb [PDF]

open access: yes, 1985
Monoclonal antibodies were raised against differentiated cells, and blastemal cells from regenerating limbs of adult newts (Notophthalmus viridescens) and screened for specific staining by immunocytochemistry.
Brockes, Jeremy P., Kintner, Chris R.
core  

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