Results 81 to 90 of about 6,006 (253)

Strategies for studying permeation at voltage-gated ion channels [PDF]

open access: yes, 1991
Voltage-dependent ion channels are presently thought to consist of several distinct functional regions: (a) activation gates, (b) inactivation gates, and permeation pathways.
Lester, Henry A.
core   +1 more source

Boosted output performance of triboelectric nanogenerator via electric double layer effect [PDF]

open access: yes, 2016
For existing triboelectric nanogenerators ( TENGs), it is important to explore unique methods to further enhance the output power under realistic environments to speed up their commercialization.
A Mills   +39 more
core   +1 more source

Neuronal voltage-gated sodium channel subtypes: Key roles in inflammatory and neuropathic pain [PDF]

open access: yes, 2006
Voltage-gated sodium channels (VGSCs) play an important role in neuronal excitability. Regulation of VGSC activity is a complex phenomenon that occurs at multiple levels in the cell, including transcriptional regulation, post-translational modification ...
Adams, D. J., Ekberg, J.
core   +1 more source

Evaluation of In Vivo and In Vitro Toxicity of Chestnut (Castanea mollissima Blume) Plant: Developmental Toxicity in Zebrafish Embryos Cytotoxicity, Antioxidant Activity, and Phytochemical Composition by LC‐ESI‐MS/MS

open access: yesFood Science &Nutrition, Volume 13, Issue 6, June 2025.
This study presents a comprehensive analysis of the water extract of chestnut (Castanea mollissima) for the first time using various antioxidant methods. The inhibitory effects of the extract towards AChE, BChE, and α‐glycosidase were evaluated. Developmental toxicity and cytotoxicity were assessed using zebrafish (Danio rerio) embryos for the extract ...
İbrahim Demirtas   +7 more
wiley   +1 more source

The singing arc: the oldest memristor?

open access: yes, 2013
On April 30th 2008, the journal Nature announced that the missing circuit element, postulated thirty-seven years before by Professor Leon O. Chua has been found.
Ginoux, Jean-Marc, Rossetto, Bruno
core   +3 more sources

Robust photoregulation of GABA(A) receptors by allosteric modulation with a propofol analogue. [PDF]

open access: yes, 2012
Photochemical switches represent a powerful method for improving pharmacological therapies and controlling cellular physiology. Here we report the photoregulation of GABA(A) receptors (GABA(A)Rs) by a derivative of propofol (2,6-diisopropylphenol), a ...
Bruzik, Karol S   +8 more
core   +2 more sources

Interface triboelectricity

open access: yesEcoEnergy, Volume 3, Issue 1, Page 105-130, March 2025.
This review systematically examines the working modes and fundamental mechanisms of liquid–solid triboelectric nanogenerators (TENGs), including the Wang Transition, hybrid EDL model, and tribovoltaic effects. The study provides insights into charge transfer at the liquid–solid interface and highlights broad applications in energy harvesting.
Jing You   +6 more
wiley   +1 more source

Messenger RNA coding for only the alpha subunit of the rat brain Na channel is sufficient for expression of functional channels in Xenopus oocytes [PDF]

open access: yes, 1986
Several cDNA clones coding for the high molecular weight (alpha) subunit of the voltage-sensitive Na channel have been selected by immunoscreening a rat brain cDNA library constructed in the expression vector lambda gt11.
Auld, Vanessa   +11 more
core  

High affinity and temperature sensitivity of blood oxygen binding in Pangasianodon hypophthalmus due to lack of chloride-hemoglobin allosteric interaction [PDF]

open access: yes, 2015
Air-breathing fishes represent interesting organisms in terms of understanding the physiological changes associated with the terrestrialization of vertebrates, and, further, are of great socio-economic importance for aquaculture in Southeast Asia.
Bayley, Mark   +5 more
core   +2 more sources

Conjugates of amiridine and salicylic derivatives as promising multifunctional CNS agents for potential treatment of Alzheimer's disease

open access: yesArchiv der Pharmazie, Volume 358, Issue 1, January 2025.
Novel conjugates of amiridine and salicylic derivatives linked with alkylene spacers were synthesized as potential multifunctional central nervous system (CNS) agents for Alzheimer's disease treatment. The conjugates exhibited high anti‐acetylcholinesterase (AChE) and anti‐butyrylcholinesterase (BChE) activities, inhibited Aβ42 self‐aggregation (up to ...
Galina F. Makhaeva   +19 more
wiley   +1 more source

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