Results 11 to 20 of about 149,767 (313)
Scientific Reports, 2021 Atrial fibrillation (AF) leads to remodeling characterized by changes in both size and shape of the left atrium (LA). Here we aimed to study the effect of hypertrophic cardiomyopathy (HCM) on the pattern of LA remodeling in AF-patients. HCM-patients (n =
Sotirios Nedios +10 more
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Safe electrophysiologic profile of dexmedetomidine in different experimental arrhythmia models
Scientific Reports, 2021 Previous studies suggest an impact of dexmedetomidine on cardiac electrophysiology. However, experimental data is sparse. Therefore, purpose of this study was to investigate the influence of dexmedetomidine on different experimental models of ...
Christian Ellermann +9 more
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Proteomic and functional analysis of HDL subclasses in humans and rats: a proof-of-concept study
Lipids in Health and Disease, 2023 Background The previous study investigated whether the functions of small, medium, and large high density lipoprotein (S/M/L-HDL) are correlated with protein changes in mice. Herein, the proteomic and functional analyses of high density lipoprotein (HDL)
Canxia Huang +14 more
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Laser-assisted Cellular Electrophysiology Measurement System [PDF]
IEEE Photonics Technology Letters, Vol 33, Issue 3, p. 163-166,
2021, 2020 Patch-clamp technique is the gold standard for cellular electrophysiological measurements, which is capable of measuring single ion transport events across the cell membrane. However, the measurement possesses significant complexity, and it requires a high level of expertise, while its experimental throughput is nevertheless considerably low.
arxiv +1 more source
Renal Failure, 2022 Purpose Glomerular mesangial cell (GMC) dysfunction plays a vital role in the pathogenesis of diabetic kidney disease (DKD). Transient receptor potential canonical 6 (TRPC6) has been demonstrated to be involved in the development of DKD.
Jian Yu +5 more
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A fast computational model for the electrophysiology of the whole human heart [PDF]
, 2021 In this study we present a novel computational model for unprecedented simulations of the whole cardiac electrophysiology. According to the heterogeneous electrophysiologic properties of the heart, the whole cardiac geometry is decomposed into a set of coupled conductive media having different topology and electrical conductivities: (i) a network of ...
arxiv +1 more source
Atrial Fibrillation Mechanisms and Implications for Catheter Ablation
Frontiers in Physiology, 2018 AF is a heterogeneous rhythm disorder that is related to a wide spectrum of etiologies and has broad clinical presentations. Mechanisms underlying AF are complex and remain incompletely understood despite extensive research.
Ghassen Cheniti +40 more
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Annals of Noninvasive Electrocardiology, 2003 Background: There is a significant difference in repolarization on the surface ECG between men and women. The effect of testosterone on repolarization of myocardium may provide a basis for the physiological and pathophysiological importance of these ...
Ata Kirilmaz +8 more
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Lidocaine as an anti‐arrhythmic drug: Are there any indications left?
Clinical and Translational Science, 2023 Lidocaine is classified as a class Ib anti‐arrhythmic that blocks voltage‐ and pH‐dependent sodium channels. It exhibits well investigated anti‐arrhythmic effects and has been the anti‐arrhythmic of choice for the treatment of ventricular arrhythmias for
Sati Güler +10 more
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Journal of Cardiovascular Magnetic Resonance, 2020 Background Data on the usefulness of cardiovascular magnetic resonance (CMR) imaging for clinical decision making in patients with an implanted cardioverter defibrillator (ICD) are scarce.
Frank Lindemann +13 more
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