Results 91 to 100 of about 20,458 (217)

The Current Role and Prospects of Electrophysiological Research Methods in Ophthalmology. Literature Review

open access: yesOftalʹmologiâ, 2020
Electrophysiological research today remains an important method for the objective assessment of the functional state of the components of the visual analyzer.There are methods, for example, OCT, that can objectively assess the structural and anatomical ...
V. N. Kazajkin   +5 more
doaj   +1 more source

Dynamin‐Related Protein 1‐Dependent Disruption of Mitochondrial Homeostasis Drives Blue Light‐Induced Epithelial‐Mesenchymal Transition in Retinal Aging

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
Blue light causes retinal injury by inducing excessive mitochondrial fission and epithelial‐mesenchymal transition in retinal pigment epithelial cells. Therapeutic targeting of Drp1 rescues this damage, restoring mitochondrial homeostasis and retinal integrity.
Zhi‐Yuan Li   +5 more
wiley   +1 more source

Topographic mapping of retinal function with the SLO-mfERG under simultaneous control of fixation in Best's disease [PDF]

open access: yes, 2003
Purpose: To introduce the scanning laser ophthalmoscope-evoked mfERG (SLO-mfERG) as a new method to measure focal retinal function. Methods: Sixty-two healthy individuals and 12 patients with Best's disease were examined.
Kalpadakis, P., Rudolph, G.
core   +1 more source

Abnormal Hearing Phenotypes in “Ignorome” Knockout Mice as Predictors of Cognitive Dysfunction

open access: yesGenes, Brain and Behavior, Volume 25, Issue 1, February 2026.
Using data from the International Mouse Phenotyping Consortium, we analyzed over 9000 knockout mouse lines to test whether sensory impairments predict behavioral abnormalities. Knockouts with abnormal hearing showed higher proportions of behavioral deficits, supporting hearing loss as a potential biomarker of cognitive vulnerability.
Sergio Vicencio‐Jimenez   +2 more
wiley   +1 more source

LncRNA DANCR Activates p38/mTOR‐Mediated Autophagy via ANXA2 to Exacerbate Oxygen‐Induced Retinal Neovascularization in Mice

open access: yesThe FASEB Journal, Volume 40, Issue 1, 15 January 2026.
This study reveals that the long non‐coding RNA DANCR drives pathological retinal neovascularization in oxygen‐induced retinopathy via an ANXA2‐dependent p38/MAPK/mTOR autophagy pathway. In hypoxic endothelial cells and a murine OIR model, DANCR promotes angiogenesis.
Yini Wang, Jiale Bai, Shihong Zhao
wiley   +1 more source

Case report: Two cases of multiple evanescent white dot syndrome with transient night blindness

open access: yesFrontiers in Ophthalmology
IntroductionThis study aimed to report two cases of multiple evanescent white dot syndrome (MEWDS) with transient night blindness.Case PresentationCase 1: A 24-year-old man presented with acute visual loss and night blindness in his right eye ...
Kanna Miyake   +3 more
doaj   +1 more source

Neurotoxicity risk assessment using of electroretinography [PDF]

open access: yes, 2015
Предложен метод усовершенствования стандартных средств электроретинографии для применения при оценивании риска нейротоксикации. На базе концепции применения низко интенсивного импульсного воздействия светом на сетчатку глаза получена большая разрешающая ...
Ткачук, Роман Андрійович   +3 more
core  

Macular dystrophy associated with the mitochondrial DNA A3243G mutation: pericentral pigment deposits or atrophy? Report of two cases and review of the literature. [PDF]

open access: yes, 2014
BACKGROUND: The A3243G point mutation in mitochondrial DNA (mtDNA) is associated with MELAS (mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes) and MIDD syndromes (maternally inherited diabetes and deafness).
Borruat, F.X., Daruich, A., Matet, A.
core   +1 more source

Effect of two week tamponade using perfluorocarbon liquid and light silicone oil on the bioelectrical functional activity in the retina in rabbits

open access: yesJournal of Ophthalmology, 2016
Introduction. Using perfluorocarbon liquid (PFCL) for short-term tamponade of the vitreous cavity expands the indications to surgical treatment of retinal detachment (RD) of various genesis.
D.V. Zhmuryk   +3 more
doaj   +1 more source

Correction of retinal ischemia/reperfusion by 3-(1H-benzimidazol-2-il)-1,2,2-trimethyl cyclopentancarbonic acid in experiment [PDF]

open access: yes, 2018
Results of ocular fundus studies revealed the most pronounced protective effects of 3-(1Hbenzimidazol-2-il)-1,2,2-trimethyl cyclopentancarbonic acid in a dose 50 mg/kg on the model of retinal ischemiareperfusion in Wistar rats, which is reflected in the ...
Bunyatyan, N. D.   +4 more
core  

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