Results 71 to 80 of about 28,602 (306)

Muscleblind-like 3 deficit results in a spectrum of age-associated pathologies observed in myotonic dystrophy. [PDF]

, 2016
Myotonic dystrophy type I (DM1) exhibits distinctive disease specific phenotypes and the accelerated onset of a spectrum of age-associated pathologies.
Abdallah, Walid F, Choi, Jongkyu, Comai, Lucio, Dansithong, Warunee, Dixon, Donald M, Jordan, Maria C, Lee, Han Shin, Reddy, Sita, Roos, Kenneth P, Trac, Brandon   +9 more
core   +1 more source

Implantable Drug Delivery Systems for Skeletal Muscles and Eyes

Advanced NanoBiomed Research, EarlyView.
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov, Murugan Ramalingam, Hongkai Wu, Toshinori Fujie, Yukinari Nakamura, Takeshi Hori, Yuji Nashimoto, Xuetao Shi, Hirokazu Kaji   +8 more
wiley   +1 more source

The Role of Sphingosine-1-Phosphate Receptor 2 in Mouse Retina Light Responses

Biomolecules, 2023
The bioactive sphingolipid sphingosine-1-phosphate (S1P) acts as a ligand for a family of G protein-coupled S1P receptors (S1PR1-5) to participate in a variety of signaling pathways. However, their specific roles in the neural retina remain unclear.
Abhishek P. Shrestha, Megan Stiles, Richard C. Grambergs, Johane M. Boff, Saivikram Madireddy, Koushik Mondal, Rhea Rajmanna, Hunter Porter, David M. Sherry, Richard L. Proia, Thirumalini Vaithianathan, Nawajes Mandal   +11 more
doaj   +1 more source

Mutations in phosphodiesterase 6 identified in familial cases of retinitis pigmentosa. [PDF]

, 2016
To delineate the genetic determinants associated with retinitis pigmentosa (RP), a hereditary retinal disorder, we recruited four large families manifesting cardinal symptoms of RP. We localized these families to regions on the human genome harboring the
Akram, Javed, Ayyagari, Radha, Gottsch, Clare Brooks S, Guru, Aditya A, Kabir, Firoz, Khan, Shaheen N, Naeem, Muhammad Asif, Riazuddin, S Amer, Riazuddin, Sheikh, Ullah, Inayat   +9 more
core   +2 more sources

Comparative Study of Accommodative Function and Binocular Vision in Patients With Primary Angle‐Closure Disease

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The age‐related decline in accommodative function after the age of 50 years corresponds with an increasing incidence of primary angle‐closure disease (PACD); however, the interaction between this decline and PACD remains unexamined. Additionally, refractive error‐accommodation associations in elderly individuals, which are critical for PACD ...
Feng‐Rui Yang, Zhi‐Qiao Liang, Ye Lu, Yao Ma, Kun Lv, Qian Zhang, Hui‐Juan Wu   +6 more
wiley   +1 more source

Maturation of the Pupil Light Reflex Occurs Until Adulthood in Mice

Frontiers in Neurology, 2019
With respect to photoreceptor function, it is well known that electroretinogram (ERG) amplitudes decrease with age, but to our knowledge, studies describing age-related changes in the pupil light response (PLR) of mice are lacking.
Noémie Kircher, Sylvain V. Crippa, Sylvain V. Crippa, Catherine Martin, Aki Kawasaki, Corinne Kostic   +5 more
doaj   +1 more source

Enhancing Electroretinogram Classification with Multi-Wavelet Analysis and Visual Transformer

Sensors, 2023
The electroretinogram (ERG) is a clinical test that records the retina’s electrical response to light. Analysis of the ERG signal offers a promising way to study different retinal diseases and disorders.
Mikhail Kulyabin, Aleksei Zhdanov, Anton Dolganov, Mikhail Ronkin, Vasilii Borisov, Andreas Maier   +5 more
doaj   +1 more source

Fear of the dark in children: is stationary night blindness the cause? [PDF]

, 2003
No abstract ...
Dutton, Gordon N., Hamilton, R., Sidiki, S.   +2 more
core   +2 more sources

Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components

Small Methods, EarlyView.
The review presents a comprehensive overview of each component of lipid nanoparticles（LNPs）and their effects on editing efficiency. It specifically highlights strategies for achieving non‐liver delivery, aiming for broader applications in gene editing. Furthermore, this review summarizes the applications of LNPs in gene editing and offers insights for ...
Fan Wu, Nei Li, Yudian Xiao, Rohan Palanki, Hannah Yamagata, Michael J. Mitchell, Xuexiang Han   +6 more
wiley   +1 more source

Frequency Doubling Technology Visual Field Loss in Fabry Subjects Related to Retinal Ganglion Cell Function as Explored by ERG and OSOME

Clinical Ophthalmology, 2022
Langis Michaud, Marie-Lou Garon, Pierre Forcier, Vasile Diaconu École d’optométrie de l’Université de Montréal, Montréal, CanadaCorrespondence: Langis Michaud, École d’optométrie de l’Université de Montréal, 3744 Jean-Brillant, Suite 260-15, Montréal ...
Michaud L, Garon ML, Forcier P, Diaconu V   +3 more
doaj