Results 51 to 60 of about 17,365 (218)

Exploring fundus‐controlled mesopic and scotopic perimetry in inherited retinal disease

Acta Ophthalmologica, EarlyView.
Abstract Purpose Microperimetry is increasingly used as an outcome measure in clinical trials for retinal disease. This study compares mesopic and scotopic microperimetry in a heterogeneous cohort of patients with inherited retinal disease to assess their suitability as clinical trial outcome measures and to determine the most appropriate testing ...
Laura J. Taylor, Amandeep S. Josan, Daniel A O Adeyoju, Isabella Farrance, Robert E. MacLaren   +4 more
wiley   +1 more source

Large-Area Photoreceptor Degeneration Model in Rabbits by Photocoagulation and Oxidative Stress in the Retina

Frontiers in Neuroscience, 2021
Photocoagulation is used for the treatment of retinal ischemic disease. However, due to the invasive nature of photocoagulation and variety of melanin concentrations between individuals, it is challenging to avoid damaging the adjacent photoreceptors and
Zhexuan Wang, Chenli Feng, Ruyi Yang, Tingting Liu, Yin Chen, Aihua Chen, Biao Yan, Yuanzhi Yuan, Jiayi Zhang   +8 more
doaj   +1 more source

Clinical manifestations of dual‐gene variants in retinitis pigmentosa

Acta Ophthalmologica, EarlyView.
Abstract Purpose Retinitis pigmentosa (RP) is an inherited retinal disease (IRD), whereby each affected individual typically harbours pathogenic variants in a single causative gene, yet the disorder exhibits marked genetic heterogeneity, with more than 100 genes reported to underlie RP.
Lasse Wolfram, Jan‐Philipp Bodenbender, David A. Merle, Milda Reith, Anton Sonntag, Krunoslav Stingl, Tobias B. Haack, Theresia Zuleger, Bernd Wissinger, Laura Kühlewein, Katarina Stingl, Susanne Kohl   +11 more
wiley   +1 more source

Retinal dystrophies simulating geographic atrophy: A diagnostic challenge

Acta Ophthalmologica, EarlyView.
Abstract Geographic atrophy (GA) is the chronic loss of retinal pigment epithelium, photoreceptors and choriocapillaris, marking the dry late stage of age‐related macular degeneration (AMD). GA prevalence is expected to rise in the upcoming decades. Advanced GA leads to central scotomas, reducing visual acuity and quality of life, potentially resulting
Johanna M. Colijn, Frank G. Holz, Jeroen Pas, Carel Hoyng   +3 more
wiley   +1 more source

Focal electroretinography in normal young adults [PDF]

, 2005
PURPOSE: To determine normative values for focal electroretinography in normal young adults, according to the standard protocol recommended by the International Society for Clinical Electrophysiology of Vision - IsCEV.
Berezovsky, Adriana [UNIFESP], Punaro, Elizabete [UNIFESP], Salomão, Solange Rios [UNIFESP]   +2 more
core   +1 more source

Electroretinography and circadian rhythm in Lycosa tarentula (Araneae, Lycosidae) [PDF]

, 1990
Electroretinography reveals the existence of a well marked circadian rhythm.
Carricaburu, Pierre, Ortega Escobar, Joaquín, Muñoz Cuevas, Arturo   +2 more
core   +1 more source

Bioactive Glial-Derived Neurotrophic Factor from a Safe Injectable Collagen–Alginate Composite Gel Rescues Retinal Photoreceptors from Retinal Degeneration in Rabbits

Marine Drugs
The management of vision-threatening retinal diseases remains challenging due to the lack of an effective drug delivery system. Encapsulated cell therapy (ECT) offers a promising approach for the continuous delivery of therapeutic agents without the need
Tingyu Hu, Ting Zhou, Rajesh Kumar Goit, Ka Cheung Tam, Yau Kei Chan, Wai-Ching Lam, Amy Cheuk Yin Lo   +6 more
doaj   +1 more source

Clinical and molecular features of PRCD‐associated retinopathy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To describe the clinical and genetic characteristics of patients with biallelic disease‐causing variants in the PRCD (Progressive Rod‐Cone Degeneration) gene. Methods Multicentre, retrospective cohort study of 19 patients from 13 families across nine reference centres in six countries.
Vasil Kostin, Karolina Kaminska, Marco Cattaneo, Enrico Ambrosini, Carmen Ayuso, Almudena Ávila‐Fernández, Béatrice Bocquet, Luisa Coutinho‐Santos, Benedetto Falsini, Lidia Fernandez‐Caballero Palomeque, Bohdan Kousal, Petra Liskova, Inmaculada Martín‐Mérida, María Juliana Ballesta‐Martínez, Daan Panneman, Susanne Roosing, Isabelle Meunier, José M. Millán, Monika Pankievič, Irene Perea‐Romero, Virginie Peter, Giorgio Placidi, Cristina Santos, Francesca Simonelli, Ana Berta Sousa, Francesco Testa, Marie Vajter, Marianna Weener, Mathieu Quinodoz, Carlo Rivolta, Giacomo Calzetti   +30 more
wiley   +1 more source

Chronic electrical stimulation with a peripheral suprachoroidal retinal implant: a preclinical safety study of neuroprotective stimulation

Frontiers in Cell and Developmental Biology
PurposeExtraocular electrical stimulation is known to provide neuroprotection for retinal cells in retinal and optic nerve diseases. Currently, the treatment approach requires patients to set up extraocular electrodes and stimulate potentially weekly due
Carla J. Abbott, Carla J. Abbott, Penelope J. Allen, Penelope J. Allen, Penelope J. Allen, Chris E. Williams, Chris E. Williams, Richard A. Williams, Richard A. Williams, Stephanie B. Epp, Owen Burns, Ross Thomas, Mark Harrison, Patrick C. Thien, Patrick C. Thien, Alexia Saunders, Ceara McGowan, Caitlin Sloan, Chi D. Luu, Chi D. Luu, David A. X. Nayagam, David A. X. Nayagam   +21 more
doaj   +1 more source

A case study of Usher’s syndrome [PDF]

Perspectives In Medical Research, 2018
Usher’s syndrome is the most common condition that affects both hearing and vision. The major symptoms of Usher’s syndrome are hearing loss and an eye disorder called retinitis pigmentosa, or RP.
Kapil S1 , Arvind R2
doaj