Results 31 to 40 of about 15,974 (222)
Retinal Functional and Structural Changes in the 5xFAD Mouse Model of Alzheimer’s Disease
Frontiers in Neuroscience, 2020 Alzheimer’s disease is characterized by the aberrant deposition of protein in the brain and is the leading cause of dementia worldwide. Increasingly, there have been reports of the presence of these protein hallmarks in the retina.
Jeremiah K. H. Lim +8 more
doaj +1 more source
, 2011 A 32-year-old woman with benign concentric annular macular dystrophy (BCAMD) was examined with multifocal electroretinography (mfERG) and microperimetry.
Murat Karaçorlu +3 more
core +1 more source
Assessing neurotoxicity risk through electroretinography with reduced light irritation intensity [PDF]
, 2023 Присвячено питанням оцінювання ризиків нейротоксикації організму людини, викликаної негативним впливом вільних радикалів наноструктур, з використанням електрофізіологічного методу дослідження – електроретинографії з низькою інтенсивністю світлового ...
Тимків, П. +3 more
core +1 more source
PharmaceuticsExcitotoxicity has been linked to the pathogenesis of several serious degenerative ocular diseases. Long-term overactivation of the NMDA receptor by glutamate in retinal ganglion cells (RGCs) results in degeneration, apoptosis and loss of function ...
Javier Rodríguez Villanueva +4 more
doaj +1 more source
Advanced Science, EarlyView.We developed the ASCAL pipeline, integrating complementary spatial transcriptomics, to construct a high‐fidelity mouse whole‐eye single‐cell atlas. Applying ASCAL to a retinal artery occlusion (RAO) model revealed spatially restricted immune activation localized to the ganglion cell layer and the selective depletion of a translationally active, outer ...
Chen Du +11 more
wiley +1 more source
Analysis of retinal function by electroretinography (ERG).
, 2016 Analysis of retinal function by electroretinography (ERG).
Jia Hui Lee (834278) +9 more
core +1 more source
Electroretinography in small animal practice
, 2017 During the last years, clinical electrophysiology has considerably improved, allowing the evaluation of the retina and visual pathways. In small animal practice, electroretinography is more useful than other diagnostic techniques for the assessment of ...
I. K. LIAPIS (Ι. Κ. ΛΙΑΠΗΣ)
core +2 more sources
Journal of Parkinson’s DiseaseElectroretinography has emerged as a promising tool for identifying retinal functional anomalies in major psychiatric and neurodevelopmental disorders, such as schizophrenia, major depressive disorder, bipolar disorder, and autism spectrum disorder ...
Victoria Soto Linan +2 more
doaj +1 more source
Neuroprotective Effect of Methylene Blue in a Rat Model of Traumatic Optic Neuropathy
PharmaceuticalsBackground: Traumatic optic neuropathy (TON) represents a major cause of vision loss worldwide, and treatment options are limited. Here, we study whether methylene blue (MB), a free radical scavenger, is able to prevent morphological and ...
Nicolás S. Ciranna +12 more
doaj +1 more source
An n‐of‐1 gene‐directed drug repurposing trial for an ultrarare genetic condition
Epilepsia, EarlyView.Abstract Objective Gain‐of‐function (GoF) variants in the KCNC1 potassium channel subunit gene (Kv3.1) cause motor/cognitive delays and hypotonia and have been associated with seizures. Fluoxetine has inhibitory effects on Kv3.1. However, open‐label nonrandomized administration is insufficient to guide clinical decision‐making in ultrarare conditions ...
Vedika Jha +13 more
wiley +1 more source