Results 231 to 240 of about 312,664 (339)

Pirin Transcriptionally Regulates PLA2G4A To Inhibit Ferroptosis in Colorectal Cancer via Lipid Profile Remodeling

Advanced Science, EarlyView.
This study identifies Pirin (PIR), an iron‐binding protein, as a critical ferroptosis suppressor in colorectal cancer through lipid membrane remodeling. PIR, induced by NRF2 during ferroptotic stress, transcriptionally regulates PLA2G4A to shift cellular lipid composition away from ferroptosis‐permissive polyunsaturated phospholipids.
Wei Shi, Yue Qi Ong, Prativa Majee, Esther SM Wong, Amhed Missael Vargas Velazquez, Kerem Fidan, Pierce Kah‐Hoe Chow, Wai Leong Tam, Ker Kan Tan, Iain Beehuat Tan, Vinay Tergaonkar   +10 more
wiley   +1 more source

Identification of the acid-induced degradation products of omeprazole and 5-hydroxyomeprazole by high resolution mass spectrometry [PDF]

, 2018
Aherne, Bahlmann, Boxall, Brenton, Bruni, Brändström, Brändström, Brändström, Cao, Halling-Sørensen, Heberer, Holčapek, Jones, Karni, Kind, Kümmerer, Lagerstrom, Lindberg, Lindberg, López-Serna, Makarov, Makarov, McLafferty, Olbe, Patiny, Schäfer, Stumpf, Watson, Weidolf   +28 more
core   +1 more source

The second life of Citrus bergamia: bioavailability analysis of a new formulation using waste-based microencapsulation as a valuable source of bioactive compounds. [PDF]

Pharmacol Rep
Serra M, Macrì R, Bonacci S, Ritorto G, Ussia S, Nucera S, Caminiti R, Ruga S, Altomare C, Tucci L, Trunfio G, Cosco D, Procopio A, Muscoli C, Mollace R, Mollace V.   +15 more
europepmc   +1 more source

Aptamer Engineering: Strategies for Discovering Functional Nucleic Acids for Next‐Generation Diagnostics and Biosensing

Advanced Science, EarlyView.
The advent of aptamers has highlighted their potential as alternatives to antibodies, overcoming limitations of structural instability and production cost. However, conventional approaches such as SELEX remain slow and labor‐intensive. This review examines recent advances in aptamer engineering, emphasizing in vitro and AI‐driven in silico strategies ...
John V. L. Nguyen, Ahlem Meziadi, Cyrill Brunner, Maureen McKeague, Lidija Malic, Maryam Tabrizian   +5 more
wiley   +1 more source

Ionic liquid electrospray beam target performance characterization. [PDF]

J Elect Propuls
Arestie SM, Marrese-Reading CM, Shaik SZ.   +2 more
europepmc   +1 more source

SpheriCal ^® ‐ESI: A dendrimer‐based nine‐point calibration solution ranging from m / z 273 to 1716 for electrospray ionization mass spectrometry peptide analysis

, 2020
Joakim Romson, Oliver Freiholtz, Anher Saeed, Adrián Soto Kronberg, A. F. Thomas, Jamie Godfrey, Michael Malkoch, Scott M. Grayson, Åsa Emmer   +8 more
openalex   +1 more source

PCR Followed by Electrospray Ionization Mass Spectrometry for Broad-Range Identification of Fungal Pathogens [PDF]

, 2013
Christian Massire, Daelynn R. Buelow, Sean X. Zhang, Robert Lovari, Heather Matthews, Donna Toleno, Raymond Ranken, Thomas A. Hall, David Metzgar, Rangarajan Sampath, Lawrence B. Blyn, David J. Ecker, Zhengming Gu, Thomas J. Walsh, Randall T. Hayden   +14 more
openalex   +1 more source

Development of Dimethylsulfonium Probes for Broad Profiling of Methyllysine Reader Proteins

Advanced Science, EarlyView.
Development of oligoglycine‐based dimethylsulfonium probes for unbiased crosslinking to methyllysine readers. The general probe facilitates profiling of site‐specific methyllysine readers, evaluation of selectivity and activity of reader inhibitors, and global profiling of methyllysine readers.
Jinyu Yang, Yihang Xiao, Yingxiao Gao, Mingxuan Wu   +3 more
wiley   +1 more source

Self-assembled polymeric nanosheet-anchored nanofiber membrane for emulsion separation. [PDF]

Nat Commun
Li H, Che K, Yin F, Liu J, Jiang P, Liu L, Li Z, Ding B, Yu J, Zhang S.   +9 more
europepmc   +1 more source

Liquid Chromatography/Electrospray Ionization/Isotopic Dilution Mass Spectrometry Analysis of n-(Phosphonomethyl) Glycine and Mass Spectrometry Analysis of Aminomethyl Phosphonic Acid in Environmental Water and Vegetation Matrixes [PDF]

, 2001
Lorna Grey, Bick Nguyen, Paul Yang
openalex   +1 more source