Results 271 to 280 of about 367,498 (388)

Overcoming EGFR‐Mediated Dendritic Cell Dysfunction to Enhance Anti‐tumor Immunity in EGFR‐Mutant NSCLC by Precisely Targeting CD73 With pH‐responsive Nanocarriers

open access: yesAdvanced Science, EarlyView.
EGFR mutations drive ERK/c‐Jun–mediated transcriptional activation of CD73, elevating adenosine levels and fostering an immunosuppressive TME by impairing DC maturation and CD8⁺ T cell priming. The pH‐responsive nanodrug F127ZIF‐8AB680 selectively inhibits CD73, normalizes adenosine metabolism, and re‐establishes effective anti‐tumor immunity ...
Xiaoling Shang   +14 more
wiley   +1 more source

Electronic‐Structure‐Guided Screening of Piperazine Derivatives: Achieving Efficient CO2 Capture with High Cyclic Capacity and Low Energy Consumption

open access: yesAdvanced Science, EarlyView.
A density functional theory (DFT)‐based framework is proposed to predict CO2 capture performance of piperazine derivatives. 2,6‐dimethylpiperazine (26DMPZ) is identified as a promising candidate: CO2‐induced precipitation in water eliminates the need for organic solvents; the low‐solubility, unstable dicarbamate enhances CO2 capture efficiency and ...
Feng Xie   +5 more
wiley   +1 more source

pH Effects on Electrospray Ionization Efficiency

open access: yesJournal of the American Society for Mass Spectrometry, 2017
Jaanus Liigand, A. Laaniste, A. Kruve
semanticscholar   +1 more source

Colored Plastic Pollution Reshapes Aquatic Microbial Community and Resistance Profile via Divergent Pseudonatural Dissolved Organic Matter

open access: yesAdvanced Science, EarlyView.
By altering the quantity and chemical composition of polyethylene‐derived dissolved organic matter, plastic color dynamically regulates bacterial metabolic interactions, thereby reshaping community resistance expression and facilitating the dissemination of antibiotic resistance.
Shuting Fang   +7 more
wiley   +1 more source

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