Results 321 to 330 of about 367,498 (388)

Observation of Near‐Infrared Photothermal and Photoacoustic Effects in a Metallosupramolecular Trefoil Knot

Angewandte Chemie, EarlyView.
A metallosupramolecular trifold knot has been prepared from three bisimidazole ligands and three dinuclear half‐sandwich metal complexes. The topology of the trifold knot enforces strong π⋅⋅⋅π interactions between the building blocks, which results in near‐infrared (NIR) light absorption.
Ye Lu, Zhi‐Jie Li, Yi Li, Lu An, Shi‐Ping Yang, F. Ekkehardt Hahn   +5 more
wiley   +1 more source

Real-time capture of reactive intermediates in an enzymatic reaction: insights into a P450-catalyzed oxidation. [PDF]

Chem Sci
Pahchan P, Nandy A, Ramireddy E, Banerjee S.   +3 more
europepmc   +1 more source

Intact Mass Profiling Reveals Phospho‐Proteoforms of the Catenins (85–110 kDa) Regulated by Actomyosin Contractility

Angewandte Chemie, EarlyView.
This study advances top‐down individual ion mass spectrometry (I2MS) to profile intact phospho‐proteoforms of β‐ and α‐catenins (85–110 kDa) within cadherin–catenin complexes. By modulating actomyosin contractility, we reveal mechano‐sensitive phosphorylation patterns and propose that distinct catenin proteoforms may reflect adhesive states at cell ...
Che‐Fan Huang, Taojunfeng Su, Annette S. Flozak, Cara J. Gottardi, Neil L. Kelleher   +4 more
wiley   +1 more source

Hydration (H₂O and D₂O) Dictates the Stabilities and Conformational Entropy of Transthyretin Tetramers. [PDF]

J Am Chem Soc
Lantz C, Rider RL, Kuo ST, Xi Z, Burningham E, Yun SD, Laganowsky A, Russell DH.   +7 more
europepmc   +1 more source

A Triple Threat Against Ovarian Cancer: Os(II)‐Pt(IV)‐Ceritinib Conjugates for Photodynamic Therapy, Chemotherapy, and Immunogenic Cell Death Induction

Angewandte Chemie, EarlyView.
A novel Os(II)‐Pt(IV)‐Ceritinib (Os‐Pt‐Cer) conjugate enables triple‐action anticancer therapy by integrating photodynamic therapy, chemotherapy, and immunogenic cell death (ICD) induction into a single molecule. Upon near‐infrared light activation, this heterobimetallic complex exhibits potent antiproliferative effects in ovarian cancer models ...
Marta Redrado, Sourav Acharya, Pierre Mesdom, Tomer Babu, James W. Southwell, Laiane S. Oliveira, Samia Hidalgo, Philippe Arnoux, Céline Frochot, Dan Gibson, Gilles Gasser   +10 more
wiley   +1 more source

Coupling Capillary Electrophoresis With a Shifted Inlet Potential High-Resolution Ion Mobility Spectrometer. [PDF]

Electrophoresis
Welters K, Thoben C, Raddatz CR, Schlottmann F, Zimmermann S, Belder D.   +5 more
europepmc   +1 more source

The Dark Metabolome/Lipidome and In-Source Fragmentation. [PDF]

Anal Sci Adv
Uritboonthai W, Hoang L, Aisporna A, Giera M, Siuzdak G.   +4 more
europepmc   +1 more source

Antibody-Drug Conjugate Stability Probed by Variable-Temperature Electrospray Ionization Mass Spectrometry. [PDF]

J Am Soc Mass Spectrom
Fiala J, Schuster D, Heck AJR.
europepmc   +1 more source

Evaluation of Violacein Metabolic Stability and Metabolite Identification in Human, Mouse, and Rat Liver Microsomes. [PDF]

Pharmaceutics
Calemi DBA, Godoi AB, Minuti G, Neto FC, Hispagnol GF, Pilon AC, Costa JL, Hyslop S, Antunes NJ.   +8 more
europepmc   +1 more source

High-Throughput Drug Derivatization and Bioassay by Desorption Electrospray Ionization Mass Spectrometry. [PDF]

Chempluschem
Ghosh J, Morato NM, Feng Y, Cooks RG.
europepmc   +1 more source