Results 1 to 10 of about 201,812 (254)
Efficiency of nano-electrospray ionization [PDF]
Journal of the American Society for Mass Spectrometry, 2005 The efficiency of nano-electrospray ionization, defined as the flux of ions reaching the detector of a triple-quadrupole mass spectrometer divided by the flux of analyte ions leaving the needle, has been measured in a series of controlled experiments with dodecyltrimethyl ammonium (DDTMA) bromide, myoglobin, Glu- [1]-fibrinopeptide, and gramicidin S ...
Bruce A. Thomson +2 more
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Principles of Electrospray Ionization [PDF]
Molecular & Cellular Proteomics, 2011 Electrospray ionization is today the most widely used ionization technique in chemical and biochemical analysis. Interfaced with a mass spectrometer it allows the investigation of the molecular composition of liquid samples. With electrospray a large variety of chemical substances can be ionized.
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Transmission mode desorption electrospray ionization [PDF]
Journal of the American Society for Mass Spectrometry, 2008 A new mode of operation for desorption electrospray ionization (DESI) analysis of liquids or solid residues from evaporated solvents is presented. Unlike traditional DESI, the electrospray is not deflected off of a surface but instead is transmitted through a sampling mesh at a 0 degrees angle between the electrospray tip, sample mesh, and capillary ...
Jennifer S. Brodbelt, Joseph E. Chipuk
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Electrospray ionization of copper—glycine solutions [PDF]
Journal of the American Society for Mass Spectrometry, 1996 We have characterized the electrospray ionization (ESI) spectra of mixtures of the 3d transition metal ion Cu(2+) with both a model amino acid (glycine) and a simple peptide system (glycylglycine). We found what appear to be two major classes of ions.
Yaodong Xu +2 more
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Electrospray Ionization on Solid Substrates
Mass Spectrometry, 2014 Development of electrospray ionization on solid substrates (solid-substrate ESI) avoids the clogging problem encountered in conventional capillary-based ESI, allows more convenient sampling and permits new applications. So far, solid-substrate ESI with various materials, e.g., metals, paper, wood, fibers and biological tissue, has been developed, and ...
Pui-Kin So, Bin Hu, Zhongping Yao
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Mechanistic investigation of ionization suppression in electrospray ionization
Journal of the American Society for Mass Spectrometry, 2000 We show results from experiments designed to determine the relative importance of gas phase processes and solution phase processes into ionization suppression observed in biological sample extracts. The data indicate that gas phase reactions leading to the loss of net charge on the analyte is not likely to be the most important process involved in ...
Richard King +4 more
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Some Thoughts on Electrospray Ionization Mechanisms
European Journal of Mass Spectrometry, 2011 Electrospray ionization (ESI) mechanisms are highly complex, due to a series of physical and chemical phenomena taking place on a complex system, as a solution is. In fact, even if the solution of an analyte in a protic medium can be considered at first sight to be a two-component system, the presence of solvent dissociation equilibria and the ...
Crotti S, Seraglia R, Traldi P
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Electrospray Ionization-Induced Protein Unfolding [PDF]
Journal of the American Society for Mass Spectrometry, 2012 Electrospray ionization mass spectrometry (ESI-MS) measurements were performed under a variety of solution conditions on a highly acidic sub-fragment (B3C) of the C-terminal carbohydrate-binding repeat region of Clostridium difficile toxin B, and two mutants (B4A and B4B) containing fewer acidic residues.
Luiz Eugenio +5 more
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How Soft Is Secondary Electrospray Ionization?
Journal of the American Society for Mass Spectrometry, 2022 ISSN:1044 ...
Jérôme Kaeslin +3 more
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Kinetic Control of Protonation in Electrospray Ionization [PDF]
Journal of the American Society for Mass Spectrometry, 2011 The site of protonation in a molecule can greatly affect the fragments observed in product ion MS/MS spectra. In electrospray positive ionization mass spectra, protonation usually occurs predominantly on the most basic site on the molecule to produce the thermodynamically favored protonated species.
J. Richard Joyce, Don S. Richards
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