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Extractive electrospray ionization mass spectrometry for analytical evaluation and synthetic preparation of pharmaceutical chemicals

open access: yesFrontiers in Pharmacology, 2023
Extraction electrospray ionization mass spectrometry (EESI-MS), due to the unique configuration of its ionization module, enables the effective ionization of trace molecules of interest in samples containing complex matrices with high sensitivity, high ...
Manman Qin   +9 more
doaj   +1 more source

Enhancing Metabolomic Coverage in Positive Ionization Mode Using Dicationic Reagents by Infrared Matrix-Assisted Laser Desorption Electrospray Ionization

open access: yesMetabolites, 2021
Mass spectrometry imaging is a powerful tool to analyze a large number of metabolites with their spatial coordinates collected throughout the sample. However, the significant differences in ionization efficiency pose a big challenge to metabolomic mass ...
Ying Xi, David C. Muddiman
doaj   +1 more source

Research Progress of Highly Selective Solid Substrate Electrospray Ionization Sources for Mass Spectrometry [PDF]

open access: yesZhipu Xuebao, 2022
Solid substrate electrospray mass spectrometry is an ambient mass spectrometry method that involves carrying, ionization and detection of the samples. This approach has a wide range of applications, and which is appropriate for rapid mass spectrometric ...
ZHANG Feng;MU Guo-dong;LIU Tong
doaj  

Transmission mode desorption electrospray ionization [PDF]

open access: yesJournal of the American Society for Mass Spectrometry, 2008
A new mode of operation for desorption electrospray ionization (DESI) analysis of liquids or solid residues from evaporated solvents is presented. Unlike traditional DESI, the electrospray is not deflected off of a surface but instead is transmitted through a sampling mesh at a 0 degrees angle between the electrospray tip, sample mesh, and capillary ...
Chipuk, Joseph E., Brodbelt, Jennifer S.
openaire   +2 more sources

Efficiency of nano-electrospray ionization [PDF]

open access: yesJournal of the American Society for Mass Spectrometry, 2005
The efficiency of nano-electrospray ionization, defined as the flux of ions reaching the detector of a triple-quadrupole mass spectrometer divided by the flux of analyte ions leaving the needle, has been measured in a series of controlled experiments with dodecyltrimethyl ammonium (DDTMA) bromide, myoglobin, Glu- [1]-fibrinopeptide, and gramicidin S ...
El-Faramawy, Ayman   +2 more
openaire   +2 more sources

Implementation of a MS/MS database for isoquinoline alkaloids and other annonaceous metabolites

open access: yesScientific Data, 2022
Measurement(s) electrospray ionization Technology Type(s) Ultra High-performance Liquid Chromatography • Tandem Mass ...
Salemon Akpa Agnès   +12 more
doaj   +1 more source

Development and Performance Test of Enclosed Extractive Electrospray Ionization Device [PDF]

open access: yesZhipu Xuebao, 2023
Extractive electrospray ionization (EESI) technology has the advantages of directly ionizing the target molecules in the samples without complex sample pretreatments, and it is widely used for analysis of complex matrix samples, especially for aerosol ...
DONG Xiao-feng1   +4 more
doaj   +1 more source

Exploiting the formation of adducts in mobile phases with ammonium fluoride for the enhancement of annotation in liquid chromatography-high resolution mass spectrometry based lipidomics

open access: yesJournal of Chromatography Open, 2021
Liquid Chromatography-High Resolution Mass Spectrometry (LC-HRMS) based lipidomics has become the most versatile analytical tool to discover and detect lipids using a non-targeted approach.
Carolina Gonzalez-Riano   +2 more
doaj   +1 more source

Desorption Electrospray Ionization (DESI) Mass Spectrometric Imaging of the Distribution of Rohitukine in the Seedling of Dysoxylum binectariferum Hook. F. [PDF]

open access: yesPLoS ONE, 2016
Ambient ionization mass spectrometric imaging of all parts of the seedling of Dysoxylum binectariferum Hook. f (Meliaceae) was performed to reconstruct the molecular distribution of rohitukine (Rh) and related compounds.
Patel Mohana Kumara   +5 more
doaj   +1 more source

Principles of Electrospray Ionization [PDF]

open access: yesMolecular & Cellular Proteomics, 2011
Electrospray ionization is today the most widely used ionization technique in chemical and biochemical analysis. Interfaced with a mass spectrometer it allows the investigation of the molecular composition of liquid samples. With electrospray a large variety of chemical substances can be ionized.
openaire   +5 more sources

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