Results 31 to 40 of about 599,586 (355)

Fragmentation reactions using electrospray ionization mass spectrometry: an important tool for the structural elucidation and characterization of synthetic and natural products.

open access: yesNatural product reports (Print), 2016
Over the last decade, the number of studies reporting the use of electrospray ionization mass spectrometry (ESI-MS) in combination with collision cells (or other activation methods) to promote fragmentation of synthetic and natural products for ...
D. Demarque   +4 more
semanticscholar   +1 more source

Some Thoughts on Electrospray Ionization Mechanisms

open access: yesEuropean Journal of Mass Spectrometry, 2011
Electrospray ionization (ESI) mechanisms are highly complex, due to a series of physical and chemical phenomena taking place on a complex system, as a solution is. In fact, even if the solution of an analyte in a protic medium can be considered at first sight to be a two-component system, the presence of solvent dissociation equilibria and the ...
Crotti S, Seraglia R, Traldi P
openaire   +5 more sources

Electrospray Ionization Mass Spectrometry: A Technique to Access the Information beyond the Molecular Weight of the Analyte

open access: yesInternational Journal of Analytical Chemistry, 2012
The Electrospray Ionization (ESI) is a soft ionization technique extensively used for production of gas phase ions (without fragmentation) of thermally labile large supramolecules.
Shibdas Banerjee, Shyamalava Mazumdar
doaj   +1 more source

FRAGMENTATION STUDIES OF D6,7-ANHIDROERITROMISIN-A BY LIQUID CHROMATOGRAPHY-MASS SPECTROSCOPY (LC-MS)

open access: yesIndonesian Journal of Chemistry, 2010
Semisynthesis of D6,7-Anhydroerythromycin-A was done by biomodification technique by addition of 0.2% INH into a culture fermentation of Saccharopolyspora erythraea ATCC 11635 in medium Hutchinson.
Khairan Khairan   +2 more
doaj   +1 more source

A tutorial in small molecule identification via electrospray ionization‐mass spectrometry: The practical art of structural elucidation

open access: yesMass spectrometry reviews (Print), 2017
The identification of unknown molecules has been one of the cornerstone applications of mass spectrometry for decades. This tutorial reviews the basics of the interpretation of electrospray ionization‐based MS and MS/MS spectra in order to identify small‐
Thomas de Vijlder   +5 more
semanticscholar   +1 more source

Think Negative: Finding the Best Electrospray Ionization/MS Mode for Your Analyte.

open access: yesAnalytical Chemistry, 2017
For the first time, the electrospray ionization efficiency (IE) scales in positive and negative mode are united into a single system enabling direct comparison of IE values across ionization modes. This is made possible by the use of a reference compound
Piia Liigand   +7 more
semanticscholar   +1 more source

Single-Cell Analysis Using Drop-on-Demand Inkjet Printing and Probe Electrospray Ionization Mass Spectrometry.

open access: yesAnalytical Chemistry, 2016
This study describes a novel method for single-cell analysis and lipid profiling by combining drop-on-demand inkjet cell printing and probe electrospray ionization mass spectrometry (PESI-MS).
Fengming Chen   +5 more
semanticscholar   +1 more source

Single Cell Metabolomics: A Future Tool to Unmask Cellular Heterogeneity and Virus-Host Interaction in Context of Emerging Viral Diseases

open access: yesFrontiers in Microbiology, 2020
Viral emergence is an unpredictable but obvious event, particularly in the era of climate change and globalization. Efficient management of viral outbreaks depends on pre-existing knowledge and alertness.
Rajesh Kumar   +3 more
doaj   +1 more source

MetFish: a Metabolomics Pipeline for Studying Microbial Communities in Chemically Extreme Environments

open access: yesmSystems, 2021
The identification and accurate quantification of metabolites using electrospray ionization-mass spectrometry (ESI-MS) in hypersaline samples is a challenge due to matrix effects.
Chengdong Xu   +16 more
doaj   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

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