Results 31 to 40 of about 230,711 (334)

Electrospray Ionization on Solid Substrates

open access: yesMass Spectrometry, 2014
Development of electrospray ionization on solid substrates (solid-substrate ESI) avoids the clogging problem encountered in conventional capillary-based ESI, allows more convenient sampling and permits new applications. So far, solid-substrate ESI with various materials, e.g., metals, paper, wood, fibers and biological tissue, has been developed, and ...
Pui-Kin So, Bin Hu, Zhongping Yao
openaire   +4 more sources

Detection of Plasmodium vivax in a child returning from India by use of broad-range PCR and electrospray ionization mass spectrometry

open access: yesEmerging Microbes and Infections, 2012
Plasmodium vivax is a common cause of imported malaria in the USA, second only to P. falciparum. We present a case of P. vivax malaria in a child returning from India. P.
Megan A Rounds   +5 more
doaj   +1 more source

Structural Plasticity and Noncovalent Substrate Binding in the GroEL Apical Domain. A study using electrospray ionization mass spectrometry and fluorescence binding studies [PDF]

open access: yes, 2002
Advances in understanding how GroEL binds to non-native proteins are reported. Conformational flexibility in the GroEL apical domain, which could account for the variety of substrates that GroEL binds, is illustrated by comparison of several independent ...
Adams   +62 more
core   +1 more source

Recent advances in experimental techniques to probe fast excited-state dynamics in biological molecules in the gas phase : dynamics in nucleotides, amino acids and beyond [PDF]

open access: yes, 2013
In many chemical reactions, an activation barrier must be overcome before a chemical transformation can occur. As such, understanding the behaviour of molecules in energetically excited states is critical to understanding the chemical changes that these ...
Hadden DJ   +6 more
core   +1 more source

Model mass spectrometric study of competitive interactions of antimicrobial bisquaternary ammonium drugs and aspirin with membrane phospholipids [PDF]

open access: yes, 2013
The aim of the study is to reveal molecular mechanisms of possible activity modulation of antimicrobial bis-quaternary ammonium compounds (BQAC) and aspirin (ASP) through noncovalent competitive complexation under their combined introduction into the ...
Gömöry, Ágnes   +3 more
core   +2 more sources

Mechanistic investigation of ionization suppression in electrospray ionization

open access: yesJournal of the American Society for Mass Spectrometry, 2000
We show results from experiments designed to determine the relative importance of gas phase processes and solution phase processes into ionization suppression observed in biological sample extracts. The data indicate that gas phase reactions leading to the loss of net charge on the analyte is not likely to be the most important process involved in ...
Richard King   +4 more
openaire   +3 more sources

Recent Applications of Ambient Ionization Mass Spectrometry for Environmental Pollutant Detection [PDF]

open access: yesZhipu Xuebao, 2023
Along with the industrial development and human society progress, large number of pollutants have been discharged to induce the environmental pollution, which have attracted global attentions.
QIN Jing-yi, OUYANG Jin, NA Na
doaj   +1 more source

Fabricating an Electrospray Ionization Chip Based on Induced Polarization and Liquid Splitting

open access: yesMicromachines, 2021
The coupling of the microfluidic chip to mass spectrometry (MS) has attracted considerable attention in the area of chemical and biological analysis.
Lvhan Zhou   +6 more
doaj   +1 more source

Quantification of sirolimus by liquid chromatography-tandem mass spectrometry using on-line solid-phase extraction [PDF]

open access: yes, 2002
Quantification of the new immunosuppressant sirolimus (syn. rapamycin; Rapamune((R))) in whole blood by chromatography is essential for its clinical use since no immunoassay is available although monitoring is mandatory.
Fleischer, Claudia   +5 more
core   +1 more source

Direct Ambient Analysis of Pharmaceutical and Ecstasy Tablets

open access: yesCHIMIA, 2006
Desorption electrospray ionization (DESI) is a new ionization technique recently introduced in analytical chemistry for the ambient analysis of surfaces by mass spectrometry.
Luc Alexis Leuthold   +6 more
doaj   +1 more source

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